Separation and determination of remnant-like particles in human serum using monoclonal antibodies to apo B-100 and apo A-I

Journal of Clinical Ligand Assay

Volumn 19, Issue 3, 1996, Pages 177-183

  Nakajima, Katsuyuki ^a,b   Okazaki, Mitsuyo ^c   Tanaka, Akira ^c   Pullinger, Clive R ^d   Wang, Tao ^a   Nakano, Takamitsu ^b   Adachi, Masakazu ^b   Havel, Richard J ^d  

^a OTSUKA PHARMACEUTICAL DEVELOPMENT AND COMMERCIALIZATION INC   (United States)

^b JAPAN IMMUNORESEARCH LABORATORIES   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Apolipoprotein B 100; Apolipoprotein E; Immunoseparation; Lipoproteins

Indexed keywords

APOLIPOPROTEIN A1; APOLIPOPROTEIN B100; EPITOPE; HIGH DENSITY LIPOPROTEIN; INTERMEDIATE DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; MONOCLONAL ANTIBODY; VERY LOW DENSITY LIPOPROTEIN;

ANTIBODY STRUCTURE; ANTIGEN ANTIBODY COMPLEX; ATHEROGENESIS; AUTOMATION; CORONARY ARTERY DISEASE; DIABETES MELLITUS; DIAGNOSTIC ACCURACY; HYPERTRIGLYCERIDEMIA; LIPOPROTEIN BLOOD LEVEL; REVIEW;

EID: 0030499734     PISSN: 10811672     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (32)

1. Kannel WB, Castelli WP, Gordon T, et al: Serum cholesterol, lipoproteins, and the risk of coronary heart disease. Ann Intern Med 1971;74:1-12.
2. Anderson KM, Castelli WP, Levy D: Cholesterol and mortality: 30 years of follow-up from the Framingham study. JAMA 1987;257:2176-2180.
3. Martin MJ, Hulley SB, Browner WS, et al: Serum cholesterol, blood pressure, and mortality: Implications from a cohort of 361662 men. Lancet 1986;2:933-939.
4. Havel RJ, Rapaport E: Management of primary hyperlipidemia. N Engl J Med 1995;332:1491-1498.
5. Castelli WP, Garrison RJ, Wilson PWF, et al: Incidence of coronary. heart disease and lipoprotein cholesterol levels. JAMA 1986;256:2835-2838.
6. Stampfer MJ, Sacks FM, Salvini S, et al: A prospective study of cholesterol, apolipoproteins and the risk of myocardial infarction. N Engl J Med 1991;325:373-381.
7. Havel RJ, Eder HA, Bragdon JH: The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J Clin Invest 1955;34:1345-1353.
8. Carroll RM, Rudel LL: Lipoprotein separation and low density lipoprotein molecular weight determination using high performance gel-filtration chromatography. J Lipid Res 1983;24:200-207.
9. Noble RP: Electrophoretic separation of plasma lipoproteins in agarose gel. J Lipid Res 1968;9:693-700.
10. Muniz N: Measurement of plasma lipoproteins by electrophoresis on polyacrylamide gel. Clin Chem 1977;23:1826-1833.
11. Wieland H, Seidel D: A simple specific method for precipitation of low density lipoproteins. J Lipid Res 1983;24:904-909.
12. McNamara JR, Cole TG, Contois JH, et. al: Immunoseparation method for measuring low-density lipoprotein cholesterol directly from serum evaluated. Clin Chem 1995;41:232-240.
13. Pisani T, Gebski CP, Leary ET, et al: Accurate direct determination of low-density lipoprotein cholesterol using an immunoseparation reagent and enzymatic cholesterol assay. Arch Pathol Lab Med 1995;119:1127-1135.
14. Campos E, Nakajima K, Tanaka A, et al: Properties of an apolipoprotein E-enriched fraction of triglyceride-rich lipoproteins isolated from human blood plasma with a monoclonal antibody to apolipoprotein B-100. J Lipid Res 1992;33:369-380.
15. Nakajima K, Saito T, Tamura A, et al: A new assay for remnant lipoproteins and its clinical significance. The quantification of serum RLP-C (remnant-like particle cholesterol) in a fasting state. J Jpn Atherosclerosis 1992;20:79-88.
16. Nakajima K, Saito T, Tamura A, et al: Cholesterol in remnant-like lipoproteins in human serum using monoclonal anti apo B-100 and anti apo A-I immunoaffinity mixed gel. Clin Chim Acta 1993;223:53-71.
17. Havel RJ: Chylomicron remnants: hepatic receptors and metabolism. Curr Opinion Lipidol 1995;6:312-316.
18. Tomono S, Kawazu S, Kato N, et al: Uptake of remnant like particles (RLP) in diabetic patients from mouse peritoneal macrophages. J Atheroscl Thromb 1994;1:98-102.
19. Tanaka A, Ejiri N, Fujinuma Y, et al: Remnant-like particles of coronary arteries after PTCA. Annals NY Acad Sci 1995;748:595-598.
20. Shimizu H, Mori M, Saito T: An increase of serum remnant-like particles in noninsulin-dependent diabetic patients with microalbuminuria. Clin Chim Acta 1993;221:191-196.
21. Fievet C, Durieux C, Mibine R et al: Rat monoclonal antibodies and human apolipoprotein B: Advantages and applications. J Lipid Res 1989;30:1015-1024.
22. Koemer TJ, Hill JE, Myers AM, et al: High-expression vectors with multiple cloning sites for construction of trp E fusion genes: pATH vectors. Methods Enzymol 1991;194:477-490.
23. Hara I, Okazaki M: High-performance liquid chromatography of serum lipoproteins. Methods Enzymol 1986;129:57-78.
24. Steinmetz A: Phenotyping of human apolipoprotein E from whole blood plasma by immunoblotting. J Lipid Res 1987;28:1364-1370.
25. Anantharamaiah GM, Jones NID, Segrest JP: An atlas of the amphipathic helical domains of human exchangeable plasma apolipoproteins, in Epand RM (ed): The Amphipathic Helix, Boca Raton. FL, CRC Press, 1993, pp 109-142
26. Eto M, Watanabe K, Makino I: Increased frequencies of apolipoprotein ε2 and ε4 alleles in patients with ischemic heart disease. Clin Genet 1989;36:183-188.
27. Nakajima K, Saito T, Tamura A, et al: A new approach for the detection of type III hyperlipoproteinemia by RLP-cholesterol assay. J Atherosclerosis Thrombosis 1994;1:30-36.
28. Inoue I: Separation of apo E rich-VLDL by immunoaffinity gel of anti B-100 monoclonal antibody. Jpn J Atheroscier Soc 1991;119:251-256.
29. Sekihara T, Nakano T, Nakajima K: High postprandial plasma remnant-like particles-cholesterol in patients with coronary artery diseases on chronic maintenance hemodialysis. Jpn J Nephrol 1996;38:220-228.
30. Horiuchi K, Aso T, Kawano K, et al: Apo E phenotypes in normolipidemic subjects and hyperlipidemic patients. Jpn J Clin Pathol 1993;41:364.
31. Phillips NR, Waters D, Havel RJ: Plasma lipoproteins and progression of coronary artery disease evaluated by angiography and clinical events. Circulation 1993;88:2762-2770.
32. Havel RJ: Postprandial hyperlipidemia and remnant lipoproteins. Curr Opinion Lipidol 1995;5:102-109.