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Volumn 16, Issue 6 B, 1996, Pages 3761-3766

Concomitant point mutation of tumor suppressor gene p53 and oncogene c-N-ras in malignant neuroendocrine pancreatic tumor

Author keywords

c N ras; Neuroendocrine tumor; Oncogenes; p53; Point mutations

Indexed keywords

ADENINE; ARGININE; CALCITONIN; CHROMOGRANIN; CYTOKERATIN; CYTOSINE; DNA; GLUCAGON LIKE PEPTIDE 1; GLYCINE; GUANINE; LYSINE; PROTEIN P53; SERINE; SYNAPTOPHYSIN; VASOACTIVE INTESTINAL POLYPEPTIDE;

EID: 0030499480     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (7)

References (29)
  • 2
    • 0026566408 scopus 로고
    • Nonfunctioning pancreatic endocrine tumors. An immunohistochemical and electron microscopic analysis of 26 cases
    • Tong-Hua Yu Z, Quan-Cai C, Li-Xing C, Sheng-Feng Y, Shou-Xian Z and Hong-Ping J: Nonfunctioning pancreatic endocrine tumors. An immunohistochemical and electron microscopic analysis of 26 cases. Path Res Pract 188: 191-198, 1992.
    • (1992) Path Res Pract , vol.188 , pp. 191-198
    • Tong-Hua, Yu.Z.1    Quan-Cai, C.2    Li-Xing, C.3    Sheng-Feng, Y.4    Shou-Xian, Z.5    Hong-Ping, J.6
  • 3
    • 0027102969 scopus 로고
    • Prospective study of aggressive resection of metastatic pancreatic endocrine tumors
    • Carty SE, Jensen RT and Norton JA: Prospective study of aggressive resection of metastatic pancreatic endocrine tumors. Surgery 112: 1024-1032, 1992.
    • (1992) Surgery , vol.112 , pp. 1024-1032
    • Carty, S.E.1    Jensen, R.T.2    Norton, J.A.3
  • 6
    • 0020084203 scopus 로고
    • Pancreatic endocrine tumors: Immunocytochemical analysis of 125 tumors
    • Heitz PU, Kasper M, Polak JM and Kloppel G: Pancreatic endocrine tumors: immunocytochemical analysis of 125 tumors. Hum Pathol 13: 263-271, 1982.
    • (1982) Hum Pathol , vol.13 , pp. 263-271
    • Heitz, P.U.1    Kasper, M.2    Polak, J.M.3    Kloppel, G.4
  • 7
    • 0019990021 scopus 로고
    • Retrospective study of 77 pancreatic endocrine tumors using the immunoperoxidase method
    • Mukai K, Grotting JC, Greider MH and Rosai J: Retrospective study of 77 pancreatic endocrine tumors using the immunoperoxidase method. Am J Surg Pathol 6: 387-399, 1982.
    • (1982) Am J Surg Pathol , vol.6 , pp. 387-399
    • Mukai, K.1    Grotting, J.C.2    Greider, M.H.3    Rosai, J.4
  • 10
    • 0027319960 scopus 로고
    • DNA amplification by polymerase chain reaction from brain tissues embedded in paraffin
    • Gall K, Pavelic J, Jadro-Santel D, Poljak M and Pavelic K: DNA amplification by polymerase chain reaction from brain tissues embedded in paraffin. Int J Exp Pathol 74: 333-337,1993.
    • (1993) Int J Exp Pathol , vol.74 , pp. 333-337
    • Gall, K.1    Pavelic, J.2    Jadro-Santel, D.3    Poljak, M.4    Pavelic, K.5
  • 13
    • 0001836496 scopus 로고
    • Production of single strended DNA by asymmetric PCR
    • PCR Protocols Innis MA, Gelfand OH, Sninsky JY, White TJ, eds Academic Press
    • McCabe IC: Production of single strended DNA by asymmetric PCR. In: PCR Protocols. A Guidline for Methods and Applications (Innis MA, Gelfand OH, Sninsky JY, White TJ, eds). Academic Press, 1990, pp 76-83.
    • (1990) A Guidline for Methods and Applications , pp. 76-83
    • McCabe, I.C.1
  • 14
    • 0001040973 scopus 로고
    • DNA sequencing with Thermus aquaticus DNA polymerase and direct sequencing of polymerase chain reaction amplified DNA
    • Innis MA, Myambo KB, Gelfand DH and Brow MA: DNA sequencing with Thermus aquaticus DNA polymerase and direct sequencing of polymerase chain reaction amplified DNA. Proc Natl Acad Sci USA 85: 9436-9440, 1988.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 9436-9440
    • Innis, M.A.1    Myambo, K.B.2    Gelfand, D.H.3    Brow, M.A.4
  • 16
    • 0024465512 scopus 로고
    • Activated N-ras oncogenes in human neuroblastoma
    • Ireland CM: Activated N-ras oncogenes in human neuroblastoma. Cancer Res 49: 5530-5533, 1984.
    • (1984) Cancer Res , vol.49 , pp. 5530-5533
    • Ireland, C.M.1
  • 17
    • 0025857633 scopus 로고
    • Low frequency of ras gene mutations in neuroblastoma. pheochromocytomas, and medullary thyroid cancers
    • Moley JF, Brother MB, Wells SA, Splengler BA, Biedler JL and Brodeur GM: Low frequency of ras gene mutations in neuroblastoma. pheochromocytomas, and medullary thyroid cancers. Cancer Res 51: 1596-1599, 1991.
    • (1991) Cancer Res , vol.51 , pp. 1596-1599
    • Moley, J.F.1    Brother, M.B.2    Wells, S.A.3    Splengler, B.A.4    Biedler, J.L.5    Brodeur, G.M.6
  • 18
    • 0027363208 scopus 로고
    • Genetic instability in pancreatic cancer and poorly differentiated type of gastric cancer
    • Han HJ, Yanagisawa A, Kato Y, Park JG and Nakamura Y: Genetic instability in pancreatic cancer and poorly differentiated type of gastric cancer. Cancer Res 53: 5087-5089, 1993.
    • (1993) Cancer Res , vol.53 , pp. 5087-5089
    • Han, H.J.1    Yanagisawa, A.2    Kato, Y.3    Park, J.G.4    Nakamura, Y.5
  • 19
    • 0028096523 scopus 로고
    • Analysis of multiple molecular changes in human endocrine tumors
    • Arany I, Rady P, Evers BM, Tyring SK and Townsend CM: Analysis of multiple molecular changes in human endocrine tumors. Surg Oncol 3: 153-159, 1994.
    • (1994) Surg Oncol , vol.3 , pp. 153-159
    • Arany, I.1    Rady, P.2    Evers, B.M.3    Tyring, S.K.4    Townsend, C.M.5
  • 20
    • 0026792908 scopus 로고
    • Role of p53 mutations in endocrine tumorigenesis: Mutation detection by polymerase chain reaction-single strand conformation polymorphism
    • Yoshimoto K, Iwanaha H, Fukuda A, Sano T, Saito S and Itakura M: Role of p53 mutations in endocrine tumorigenesis: mutation detection by polymerase chain reaction-single strand conformation polymorphism. Cancer Res 52: 5061-5064, 1992.
    • (1992) Cancer Res , vol.52 , pp. 5061-5064
    • Yoshimoto, K.1    Iwanaha, H.2    Fukuda, A.3    Sano, T.4    Saito, S.5    Itakura, M.6
  • 21
    • 0025828517 scopus 로고
    • Selective G to T mutations of. p53 gene in hepatocellular carcinoma from southern Africa
    • Bressac B, Kew M, Wands J and Ozturk M: Selective G to T mutations of. p53 gene in hepatocellular carcinoma from southern Africa. Nature 350: 429-431, 1991.
    • (1991) Nature , vol.350 , pp. 429-431
    • Bressac, B.1    Kew, M.2    Wands, J.3    Ozturk, M.4
  • 22
    • 0025732215 scopus 로고
    • Mutational hotspot in the p53 gene in human hepatocellular carcinomas
    • Hsu IC, Metcalf RA, Sun T, Welsh JA, Wang NJ and Harris CC: Mutational hotspot in the p53 gene in human hepatocellular carcinomas. Nature 350: 427-428, 1991.
    • (1991) Nature , vol.350 , pp. 427-428
    • Hsu, I.C.1    Metcalf, R.A.2    Sun, T.3    Welsh, J.A.4    Wang, N.J.5    Harris, C.C.6
  • 24
    • 0027733796 scopus 로고
    • K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele specific oligonucleotide hybridization
    • Hruban RH, van Mansfeld ADM, Offerhaus GJA, van Weering DHJ, Allison DC, Goodman SN, Kensler TW, Bose KK, Cameron JL, Bos JL: K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele specific oligonucleotide hybridization. Am J Pathol 143: 545-554, 1993.
    • (1993) Am J Pathol , vol.143 , pp. 545-554
    • Hruban, R.H.1    Van Mansfeld, A.D.M.2    Offerhaus, G.J.A.3    Van Weering, D.H.J.4    Allison, D.C.5    Goodman, S.N.6    Kensler, T.W.7    Bose, K.K.8    Cameron, J.L.9    Bos, J.L.10
  • 26
    • 0025275853 scopus 로고
    • C-Ha-ras oncogene expression in immortalized human keratinocytes (HaCaT) alters growth potential in vivo hut lacks correlation with malignancy
    • Boukaps P, Stanbridge EJ, Yin Foo D, Cerutti PA and Fusenig NE: c-Ha-ras oncogene expression in immortalized human keratinocytes (HaCaT) alters growth potential in vivo hut lacks correlation with malignancy. Cancer Res 50: 2840-2847, 19911.
    • (1991) Cancer Res , vol.50 , pp. 2840-2847
    • Boukaps, P.1    Stanbridge, E.J.2    Yin Foo, D.3    Cerutti, P.A.4    Fusenig, N.E.5
  • 27
    • 0024280502 scopus 로고
    • The cytoplasmic protein GAP is implicated as the target for regulation by the ras gene product
    • Cales C, Hancock JF, Marshall CJ and Hall A: The cytoplasmic protein GAP is implicated as the target for regulation by the ras gene product. Nature 332: 548-551,1988.
    • (1988) Nature , vol.332 , pp. 548-551
    • Cales, C.1    Hancock, J.F.2    Marshall, C.J.3    Hall, A.4
  • 28
    • 0027996474 scopus 로고
    • Ras antagonizes cAMP stimulated glucagon gene transcription in pancreatic islet cell lines
    • Gherzi R, Briata P, Fehman HC and Goke B: ras antagonizes cAMP stimulated glucagon gene transcription in pancreatic islet cell lines. FEBS Letters 353: 277-280,1994.
    • (1994) FEBS Letters , vol.353 , pp. 277-280
    • Gherzi, R.1    Briata, P.2    Fehman, H.C.3    Goke, B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.