The roles of Fas and perforin in LAK T-cell/bispecific antibody-mediated killing of the murine B-lymphoma cells, BCL1

International Journal of Cancer

Volumn 68, Issue 6, 1996, Pages 822-827

  Armstrong, John M ^a   Vitetta, Ellen S ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BISPECIFIC ANTIBODY; FAS ANTIGEN; PERFORIN;

ANIMAL CELL; ANTIBODY PRODUCTION; ARTICLE; B CELL LYMPHOMA; CONTROLLED STUDY; LYMPHOKINE ACTIVATED KILLER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR CELL DESTRUCTION;

ANIMALS; ANTIBODIES, BISPECIFIC; ANTIBODY-DEPENDENT CELL CYTOTOXICITY; ANTIGENS, CD95; CHROMIUM; FEMALE; FLOW CYTOMETRY; GENES, BCL-2; KILLER CELLS, LYMPHOKINE-ACTIVATED; LYMPHOMA, B-CELL; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; PORE FORMING CYTOTOXIC PROTEINS; T-LYMPHOCYTES, CYTOTOXIC;

EID: 0030499378     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19961211)68:6<822::AID-IJC22>3.0.CO;2-0     Document Type: Article

References (21)

1. BAUER, T. and DRAKEMAN, D.L., Bispecific antibodies and targeted cellular cytoxicity: therapeutic hopes confirmed. Vox Sang, 61, 156-157 (1991).
2. BRENNAN, M., DAVISON, P.F. and PAULUS, H., Preparation of bispecific antibodies by chemical recombination of monoclonal immunoglobulin G1 fragments. Science (Wash.), 229, 81-83 (1985).
3. BROOKS, K., D. YUAN, J.W. UHR, P.H. KRAMMER AND E.S. VITETTA. Lymphokine-induced IgM secretion by clones of neoplastic B cells. Nature 302, 825-826, 1983.
4. BRUNNER, T., MOGIL, R.J., LE FACE, D., YOO, N.J., MAHBOUBI, A., ECHEVERRI, F., MARTIN, S.J., FORCE, W.R., LYNCH, D.H., WARE, C.F. and GREEN, D.R., Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature (Lond.), 373, 441-444 (1995).
5. CASCINO, I., FIUCCI, G., PAPOFF, G. and RUBERTI, G., Three functional soluble forms of the human apoptosis-inducing fas molecule are produced by alternative splicing. J. Immunol., 154, 2706-2713 (1995).
6. COULIE, P.O., UYTTENHOVE, C., WAUTERS, P., MANOLIOS, N., KLAUSNER, R.D., SAMELSON, L.E. and VAN SNICK, J., Identification of a murine monoclonal antibody specific for an allotypic determinant on mouse CD3. Europ. J. Immunol., 21, 1703-1709 (1991).
7. DEMANET, C., BRISSINCK, J., LEO, O., MOSER, M.and THIELEMANS, K., Role of T-cell subsets in the bispecific antibody (anti-idiotype x antiCD3) treatment of the BCL1 lymphoma. Cancer Res., 54, 2973-2978 (1994).
8. 1. J. Immunol., 138, 628-634 (1987).
9. HAHNE, M., RENNO, T., SCHROETER, M., IRMLER, M., FRENCH, L., BORNAND, T., MACDONALD, H.R. and TSCHOPP, J., Activated B cells express functional Fas ligand. Europ. J. Immunol., 26, 721-724 (1996).
10. HELLER, R.A., SONG, K., ONASCH, M.A., FISCHER, W.H., CHANG, D. and RINFGOLD, G.M., Complementary DNA cloning of a receptor for tumor necrosis factor and demonstration of a shed form of the receptor. Proc. nat. Acad. Sci. (Wash.), 87, 6151-6155 (1990).
11. HENKART, P.A., Mechanism of lymphocyte-mediated cytotoxicity. Ann. Rev. Immunol., 3, 31-58 (1985).
12. KOHNO, T., BREWER, M.T., BAKER, S.L., SCHWARTZ, P.E., KING, M.W., HALE, K.K., SQUIRES, C.H., THOMPSON, R.C. and VANNICE, J.L., A second tumor necrosis factor gene product can shed a naturally occurring tumor necrosis factor inhibitor. Proc. nat. Acad. Sci. (Wash.), 87, 8331-8335 (1990).
13. ITOH, N., YONEHARA, S., ISHII, A., YONEHARA, M., MITZUSHIMA, S., SOMESHIMA, M., HASE, A., SETO, Y. and NAGATA, S., The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell, 66, 233-243 (1991).
14. Ju, S., PANKA, D.J., CUL, H., ETTINGER, R., EL-KHATIB, M., SHERR, D.H., STANGER, B.Z. and MARSHAK-ROTHSTEIN, A., Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation. Nature (Lond.), 373, 444-448 (1995).
15. OZDEMIRIL, M., EL-KHATIB, M., FOOTE, L.C., WANG, J.K.M., MARSHAK-ROTHSTEIN, A., ROTHSTEIN, T.L. and JU, S., Fas (CD95)/Fas ligand interactions regulate antigen-specific, major histocompatibility complex-restricted T/B cell proliferative responses. Europ. J. Immunol., 26, 415-419 (1996).
16. ROTHSTEIN, T.L., WANG, J.K.M., PANKA, D.J., FOOTE, L.C., WANG, Z.H., STANGER, B., CUI, H., JU, S.T. and MARSHAK-ROTHSTEIN, A., Protection against fas-dependent th1-mediated apoptosis by antigen receptor engagement in B cells. Nature (Lond.), 374, 163-165 (1995).
17. SHEN, G., LI, J. and VITETTA, E.S., A Bispecific anti-CD22/anti-CD3-ricin A chain immunotoxin is cytotoxic to Daudi lymphoma cells but not T cells in vitro and shows both A-chain-mediated and LAK-T-mediated killing. J. Immunol., 152, 2368-2376 (1994).
18. SLAVIN, S. and STROBER, S., Spontaneous murine B-cell leukaemia. Nature (Lond.), 272, 624-626 (1978).
19. TRAUTH, B.C., KLAS, C., PETERS, A.M.J., MATZKU, S., MOLLER, P., FALK, W., DEBATIN, K. and KRAMMER, P.H., Monoclonal antibody-mediated tumor regression by induction of apoplosis. Science (Wash.), 245, 301-305 (1989).
20. WALSH, C.M., GLASS, A.A., CHIU, V. and CLARK, W.R., The role of the fas lytic pathway in a perforin-less CTL hybridoma. J. Immunol., 153, 2506-2514 (1994).
21. YONEHARA, S., ISHII, A. and YONEHARA, M., A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor. J. exp. Med., 169, 1747-1756 (1989).