Nucleotide sequence of precore region of hepatitis B virus DNA in HBsAg-positive carriers in Malaysia

Scandinavian Journal of Infectious Diseases

Volumn 28, Issue 6, 1996, Pages 543-548

  Ton, S H ^a,c   Iskandar, K ^a   Noriah, R ^a   Thanaletchimy, N ^b  

^a UNIVERSITI KEBANGSAAN MALAYSIA   (Malaysia)

^b Tengku Ampuan Rahimah Hospital   (Malaysia)

^c DEPARTMENT OF PHARMACOLOGY   (Malaysia)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B(E) ANTIGEN; VIRUS DNA;

ADOLESCENT; ADULT; ARTICLE; CLINICAL ARTICLE; CODON; CONTROLLED STUDY; DISEASE CARRIER; DNA SEQUENCE; ENZYME ACTIVITY; FEMALE; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; MALAYSIA; MALE; NUCLEOTIDE SEQUENCE; STOP CODON; VIREMIA; VIRUS MUTANT;

EID: 0030498695     PISSN: 00365548     EISSN: None     Source Type: Journal    
DOI: 10.3109/00365549609037957     Document Type: Article

References (17)

1. Carmen WF, Jacyna MR, Hadziyannis S, Karayiannis P, McGarvey MJ, Makris A, Thomas HC. Mutation preventing formation of hepatitis e antigen in patients with chronic hepatitis B infection. Lancet ii: 588-591, 1989.
2. Chu CM, Karayiannis P, Fowler MJF, Monjardino J, Liew YF, Thomas HC. Natural history of chronic hepatitis B virus infection in Taiwan: studies of hepatitis B virus DNA in serum. Hepatology 5: 431-434, 1985.
3. Hadziyiannis SJ, Lieberman HM, Karvountzis MG, Shafritz D. Analysis of liver disease, nuclear HBcAg, viral replication and hepatitis B virus in liver and serum of HBeAg vs anti-HBe positive chronic hepatitis B infection. Hepatology 3: 652-662, 1983.
4. Carmen WF, Ferrao M, Lok ASF, Ma OCK, Lai CL, Thomas HC. Precore sequence variation in Chinese isolates of hepatitis B virus. J Infect Dis 165: 127-133, 1992.
5. Brunetto MR, Stemmler M, Schodel F, Will H, Ottobvelli A, Rizetto M, Verme G, Bonino F. Identification of HBV variants which cannot produce precore-derived HBeAg and may be responsible for severe hepatitis, Ital J Gastroenterology 21: 151-154, 1989.
6. Tong S, Li J, Vitvitski L, Kay A, Trepo C. Active hepatitis B virus replication in the presence of anti-HBe is associated with viral variants containing an inactive precore. Virology 176: 596-603. 1990.
7. Okamoto H, Yotsumoto S, Akahane Y, Yamanata T, Miyazaki Y, Sugai Y, Tsuda F, Tanaka T, Miyakawa Y, Mayumia M. Hepatits B viruses with precore region defects prevail in persistently infected hosts along with seroconversion to antibody against e antigen. J Virol 64: 1298-1303, 1990.
8. Ton SH, Lim LH, Noriah R, Thanaletchimy N, Cheong SK. Serum HBV-DNA in blood donors. Malaysian J Med Lab Sci 7: 12-14, 1990.
9. Ton SH, Yeoh KS, Lim WC, Noriah R, Cheong SK, Thanaletchimy N. Infectiousness of HBsAg carriers in Malaysia. J Trop Med Hyg 98: 277-280, 1995.
10. Weller IVD, Fowler MJF, Monjardino J, Thomas HC. The detection of HBV-DNA in serum by molecular hybridization-A more sensitive method for the detection of complete HBV particles. J Virol 9: 273-288. 1982.
11. Carman WF, Thomas HC. Genetically defined variants of hepatitis B virus. Med Virol 1: 29-39, 1991.
12. Evans, DMA, Dunn G, Minor PD, Schild GC, Conn AJ, Stanway G, Almond JW. Currey K, Maizel Jr JV. A single nucleotide change in the 5(non-coding region of the genome of the Sabin type 3 polio vaccine is asociated with increased neurovirulence. Nature 314: 548-550, 1985.
13. Ganem D, Varmus HE. The molecular biology of the hepatitis viruses. A Rev Biochem 56: 651-693, 1989.
14. Kozak M. At least six nucleotides preceding AUG initiator codon enhance translation in mammalian cells. J Molec Biol 196: 947-950, 1987.
15. Laskus T, Rakele J, Parsing DH. The stem-loop structure of the cis-encapsidation signal is highly conserved in naturally occurring hepatitis B virus variants. Virology. 200: 809-812, 1994.
16. Lindh M, Yasushi F, Vahlne A, Norkrans G. Horal P. Emergence of precore TAG mutation during hepatitis B seroconversion and its dependence on pregenomic base pairing between nucleotides 1858 and 1896. J Infect Dis 172: 1343-1347, 1995.
17. Harrison TJ and Zukerman AJ. Variants of hepatitis B virus. Vox Sang 63: 161-167, 1990