Evidence that presynaptic changes are involved in the expression of LTP and LTD of NMDA receptor-mediated EPSCs in area CA1 of the hippocampus

Journal of Physiology Paris

Volumn 90, Issue 5-6, 1996, Pages 311-

  Clark, K A ^a,b   Collingridge, G L ^b  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b SCHOOL OF MEDICAL SCIENCES   (United Kingdom)

Author keywords

Coefficient of variation; long term depression; Long term potentiation; NMDA receptor; Probability of transmitter release (Pr)

Indexed keywords

N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL TISSUE; CONFERENCE PAPER; EXCITATORY POSTSYNAPTIC POTENTIAL; HIPPOCAMPUS; LONG TERM POTENTIATION; NERVE CELL PLASTICITY; NEUROTRANSMITTER RELEASE; NONHUMAN; PATCH CLAMP; RAT; SYNAPTIC INHIBITION; SYNAPTIC TRANSMISSION;

EID: 0030498521     PISSN: 09284257     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-4257(97)87904-1     Document Type: Conference Paper

References (5)

1. Bashir ZI, Alford S, Davies SN, Randall AD, Collingridge GL (1991) Long-term potentiation of NMDA receptor-mediated synaptic transmission in the hippocampus. Nature 349, 156-158
2. Hessler NA, Shirke AM, Malinow R (1993) The probability of transmitter release at a mammalian central synapse. Nature 366, 569-572
3. Manabe T, Nicoll RA (1994) Long-term potentiation: Evidence against an increase in transmitter release probability in the CA1 region of the hippocampus. Science 265, 1888-1892
4. Selig DK, Hjelmstad GO, Herron C, Nicoll RA, Malenka RC (1995) Independent mechanisms for long-term depression of AMPA and NMDA responses. Neuron 15, 417-426
5. Xie X, Berger TW, Barrionuevo G (1992) Isolated NMDA receptor-mediated synaptic responses express both LTP and LTD. J Neurophysiol 67, 1009-1013