Isolation and genetic analysis of fetal nucleated red blood cells from maternal blood: the Baylor College of Medicine experience

Early Human Development

Volumn 47, Issue SUPPL., 1996, Pages

  Elias, Sherman ^a,b   Lewis, Dorothy E ^a   Bischoff, Farideh Z ^a   Simpson, Joe Leigh ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Fetal nucleated red blood cells; Genetic analysis; Maternal blood

Indexed keywords

ANEUPLOIDY; CELL ISOLATION; CHROMOSOME ABERRATION; CONFERENCE PAPER; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; ERYTHROBLAST; FETUS CELL; GENETIC ANALYSIS; HUMAN; MATERNAL BLOOD; POLYMERASE CHAIN REACTION; PRENATAL DIAGNOSIS;

EID: 0030497824     PISSN: 03783782     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-3782(96)01828-2     Document Type: Conference Paper

References (8)

1. Bianchi, D.W., Flint, A.F., Pizzimenti, M.F., Knoll, J.H.M. and Latt, S.A. (1990): Isolation of fetal DNA from nucleated erythrocytes in maternal blood. Proc. Natl. Acad. Sci. USA, 87, 3279-3283.
2. Wachtel, S.S., Elias, S., Price, J., Wachtel, G., Phillips, O., Shulman, L., Meyers, C., Simpson, J.L. and Dockter, M. (1991): Fetal cells in the maternal circulation: isolation by multiparameter flow cytometry and confirmation by PCR. Hum. Reprod., 6, 1466-1469.
3. Price, J., Elias, S., Wachtel, S.S., Klinger, K., Dockter, M., Tharapel, A., Shulman, L.P., Philips, O.P., Meyers, C.M., Shook, D. and Simpson, J.L. (1992): Prenatal diagnosis using fetal cells isolated from maternal blood by multiparameter flow cytometry. Am. J. Obstet. Gynecol., 165, 1731-1737.
4. Simpson, J.L. and Elias, S. (1993): Isolating fetal cells from maternal blood: advances in prenatal diagnosis through molecular technology. J. Am. Med. Assoc., 270, 2357-2361.
5. Elias, S. and Simpson, J.L. (1994): Prenatal diagnosis of aneuploidy using fetal cells isolated from maternal blood: University of Tennessee, Memphis experience. In: Fetal Cells in Maternal Blood: Prospects for Noninvasive Prenatal Diagnosis, Vol. 731, pp. 80-91. Editors: J.L. Simpson and S. Elias. New York Academy of Science, New York.
6. Elias, S., Price, J., Dockter, M., Wachtel, S., Tharapel, A. and Simpson, J.L. (1992): First trimester prenatal diagnosis of trisomy 21 in fetal cells from maternal blood. Lancet, 340, 1033.
7. Lewis, D.E., Schober, W., Murrell, S., Mguyen, D., Scott, J., Simpson, J.L., Bischoff, F.Z. and Elias, S. (1996): Rare event selection of fetal nucleated erythrocytes in maternal blood by flow cytometry. Cytometry, 23, 218-227.
8. Bischoff, F.Z., Lewis, D.E., Mguyen, D.D., Murrell, S., Schober, W., Scott, J., Simpson, J.L. and Elias, S. (1996): Greatly increased efficiency of analysis of fetal cells from maternal blood: identification of fetal cells based on CD71 expression, lack of beta globin expression and use of gamma globin mRNA to distinguish fetal (XX) from maternal (XX) cells. J. Soc. Gynecol. Invest., 3 (Suppl), 361A.