Antiallergic activity of topical lodoxamide on in vivo and in vitro models

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 51, Issue 12, 1996, Pages 946-951

  Ciprandi, G ^a   Buscaglia, S ^a   Catrullo, A ^a   Paolieri, F ^a   Riccio, A M ^a   Fiorino, N ^a   Canonica, G W ^a,b  

^a UNIVERSITY OF GENOA   (Italy)

^b Allerg and Clin Immunology Service   (Italy)

Author keywords

adhesion molecules; allergen specific conjunctival challenge; allergic conjunctivitis; ICAM 1; lodoxamide

Indexed keywords

EYE DROPS; GAMMA INTERFERON; INTERCELLULAR ADHESION MOLECULE 1; LODOXAMIDE;

ADULT; ALLERGIC CONJUNCTIVITIS; ALLERGIC RHINITIS; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; ENZYME LINKED IMMUNOSORBENT ASSAY; EOSINOPHIL; FEMALE; HUMAN; MALE; NEUTROPHIL; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TOPICAL DRUG ADMINISTRATION;

EID: 0030497741     PISSN: 01054538     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1398-9995.1996.tb04499.x     Document Type: Article

References (12)

1. Ciprandi G, Buscaglia S, Cerqueti P, Canonica GW. Drug treatment of allergic conjunctivitis. A review of the evidence. Drugs 1992;43:154-76.
2. Ungerer RG, Tashkin DP, Siegel SC, Deutsch RI. Effect of inhaled lodoxamide tromethamine in prevention of antigen-induced bronchospasm. J Allergy Clin Immunol 1981; 68(6):471-8.
3. Johnson HG, Bach MK. Prevention of calcium ionophore-induced release of histamine in rat mast cells by disodium cromoglycate. J Immunol 1975;114:514-16.
4. Fridovich I. Quantitative aspects of the production of superoxide anion radical by milk xanthine oxidase. J Biol Chem 1970;245:4053-7.
5. Johnson HG. New anti-allergy drugs - the lodoxamides. Trends Pharmacol Sci 1980;1:343.
6. Yanni JM, Weimer J, Glaser RL, Lang LS, Robertson SM, Spellman JM. Effect of lodoxamide on in vitro and in vivo conjunctival immediate hypersensitivity responses in rats. Int Arch Allergy Immunol 1993;101:102-6.
7. Ciprandi G, Buscaglia S, Pesce GP, et al. Cetirizine reduces inflammatory cell recruitment and ICAM-1/CD54 expression on conjunctival epithelium both in early and late phase events following allergen specific challenge. J Allergy Clin Immunol 1995;95(2):612-21.
8. Cordell JL, Falini B, Erber WN, et al. Immunoenzymatic labelling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes). J Histochem Cytochem 1984;32:219-45.
9. Abelson MB, Schaefer K. Conjunctivitis of allergic origin: immunologic mechanisms and current approaches to therapy. Surv Ophthalmol 1993;38 Suppl:115-32.
10. Collum LMT, Bloch-Michel E, Bonomi L, et al. A three month clinical evaluation of topical lodoxamide tromethamine on the control of allergic conjunctivitis. Proceedings of XXVI International Congress of Ophthalmology, Singapore, 1990.
11. Cerqueti MP, Ricca V, Tosca MA, Buscaglia S, Ciprandi G. Lodoxamide treatment of allergic conjunctivitis. Int Arch Allergy Immunol 1994;105:185-9.
12. Ciprandi G, Buscaglia S, Albano M, et al. Nedocromil sodium and immune response. J Invest Allergol Clin 1993;3(6):311-14.