A new furostanol saponin with six sugars from the bulbs of Allium sphaerosephalon structural elucidation by modern NMR techniques

Chemistry Letters

Volumn , Issue 6, 1996, Pages 431-432

  Mimaki, Yoshihiro ^a   Satou, Tadaaki ^a   Kuroda, Minpei ^a   Kameyama, Aiko ^a   Sashida, Yutaka ^a   Li, Hong Yu ^b   Harada, Nobuyuki ^b  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0030488561     PISSN: 03667022     EISSN: None     Source Type: Journal    
DOI: 10.1246/cl.1996.431     Document Type: Article

References (9)

1. T. Inoue, Y. Mimaki, Y. Sashida, A. Nishino, Y. Satomi, and H. Nishino, Phytochemistry, 40, 521 (1995).
2. P. K. Agrawal, D. C. Jain, R. K. Gupta, and R. S. Thakur, Phytochemistry, 40, 521 (1985), and references cited therein.
3. 4 (11 : 1) to remove exchangeable protons and minimize signal overlap.
4. The monosaccharides were identified by converting them to the 1 -[(S)-N-acetyl-α-amethylbenzylamino]-1-deoxyalditol acetate derivatives followed by HPLC analysis: R. Oshima, Y. Yamauchi, and J. Kumanotani, Carbohydr. Res., 107, 169 (1982).
5. The C-22α configuration was confirmed by an NOE between 16α-H and 22-OMe in the pNOESY spectrum.
6. For example: Y. Takaashi, Y. Mimaki, M. Kuroda, Y. Sashida, T. Nikaido, and T. Ohmoto, Tetrahedron, 51, 2281 (1995).
7. P. K. Agrawal, Photochemistry, 31, 3307 (1992).
8. Y. Mimaki, Y. Sashida, and Y. Kawashima, Phytochemistry, 30, 3721 (1991).
9. The assay was carried out according to a modified method of Sargent and Tayler: J. M. Sargent and C. G. Tayler, Br. J. Cancer, 60, 206 (1989).