-
4
-
-
0017323836
-
Plasma pyridostigmine levels in patients with myasthenia gravis
-
T. N. Calvey and K. Chan. Plasma pyridostigmine levels in patients with myasthenia gravis. Clin. Pharmacol. Ther. 21:187-193 (1977).
-
(1977)
Clin. Pharmacol. Ther.
, vol.21
, pp. 187-193
-
-
Calvey, T.N.1
Chan, K.2
-
5
-
-
0019493980
-
Plasma pyridostigmine levels in myasthenia gravis
-
M. C. White, P. D. Silva, and C. W. H. Havard. Plasma pyridostigmine levels in myasthenia gravis. Neurology 31:145-150 (1981).
-
(1981)
Neurology
, vol.31
, pp. 145-150
-
-
White, M.C.1
Silva, P.D.2
Havard, C.W.H.3
-
6
-
-
0021281032
-
Steady state kinetics of pyridostigmine in myasthenia gravis
-
P. S. Sørensen, H. Flachs, M. L. Friis, E. F. Hvidberg, and O. B. Paulson. Steady state kinetics of pyridostigmine in myasthenia gravis. Neurology 34:1020-1024 (1984).
-
(1984)
Neurology
, vol.34
, pp. 1020-1024
-
-
Sørensen, P.S.1
Flachs, H.2
Friis, M.L.3
Hvidberg, E.F.4
Paulson, O.B.5
-
8
-
-
0021844145
-
Pyridostigmine kinetics in healthy subjects and patients with myasthenia gravis
-
U. Breyer-Pfaff, U. Maier, A. M. Brinkmann, and F. Schumm. Pyridostigmine kinetics in healthy subjects and patients with myasthenia gravis. Clin. Pharmacol. Ther. 37:495-501 (1985).
-
(1985)
Clin. Pharmacol. Ther.
, vol.37
, pp. 495-501
-
-
Breyer-Pfaff, U.1
Maier, U.2
Brinkmann, A.M.3
Schumm, F.4
-
9
-
-
0019206316
-
Pharmacokinetics and oral bioavailability of pyridostigmine in man
-
S.-M. Aquilonius, S.-Å. Eckernäs, P. Hartvig, B. Lindström, and P. O. Osterman Pharmacokinetics and oral bioavailability of pyridostigmine in man. Eur. J. Clin. Pharmacol. 18:423-423 (1980).
-
(1980)
Eur. J. Clin. Pharmacol.
, vol.18
, pp. 423-423
-
-
Aquilonius, S.-M.1
Eckernäs, S.-Å.2
Hartvig, P.3
Lindström, B.4
Osterman, P.O.5
-
10
-
-
0017348386
-
Malabsorption of pyridostigmine in patients with myasthenia gravis
-
S. L. Cohan, K. L. Dretchen, and A. Neal. Malabsorption of pyridostigmine in patients with myasthenia gravis. Neurology 27:299-301 (1977).
-
(1977)
Neurology
, vol.27
, pp. 299-301
-
-
Cohan, S.L.1
Dretchen, K.L.2
Neal, A.3
-
13
-
-
8044220637
-
Excretion of neostigmine labeled with carbon-14 in urine
-
J. B. Roberts, B. H. Thomas, and A. Wilson. Excretion of neostigmine labeled with carbon-14 in urine. Nature 200:1330 (1963).
-
(1963)
Nature
, vol.200
, pp. 1330
-
-
Roberts, J.B.1
Thomas, B.H.2
Wilson, A.3
-
17
-
-
8044257484
-
Determination of neostigmine and pyridostigmine in the urine of patients with myasthenia gravis
-
P. T. Nowell, C. A. Scott, and A. Wilson. Determination of neostigmine and pyridostigmine in the urine of patients with myasthenia gravis. Br. J. Pharmacol. 18:617-624 (1962).
-
(1962)
Br. J. Pharmacol.
, vol.18
, pp. 617-624
-
-
Nowell, P.T.1
Scott, C.A.2
Wilson, A.3
-
18
-
-
0018379298
-
Pharmacokinetic study of neostigmine in man using gas chromatographymass spectrometry
-
S.-M. Aquilonius, S.-Å. Eckernäs, P. Hartvig, J. Hultman, B. Lindström, and P. O. Osterman. Pharmacokinetic study of neostigmine in man using gas chromatographymass spectrometry. Eur. J. Clin. Pharmacol. 15:367-371 (1979).
-
(1979)
Eur. J. Clin. Pharmacol.
, vol.15
, pp. 367-371
-
-
Aquilonius, S.-M.1
Eckernäs, S.-Å.2
Hartvig, P.3
Hultman, J.4
Lindström, B.5
Osterman, P.O.6
-
19
-
-
0015314539
-
14C-edrophonium and its metabolites in bile: The role of the liver cell and the peribiliary vascular plexus
-
14C-edrophonium and its metabolites in bile: The role of the liver cell and the peribiliary vascular plexus. Br. J. Pharmacol. 44:534-543 (1972).
-
(1972)
Br. J. Pharmacol.
, vol.44
, pp. 534-543
-
-
Back, D.J.1
Calvey, T.N.2
-
21
-
-
0017116937
-
The effect of edrophonium on erythrocyte acetylcholinesterase and neuromuscular function in the rate
-
H. E. Barber, T. N. Calvey, K. T. Muir, and K. Taylor. The effect of edrophonium on erythrocyte acetylcholinesterase and neuromuscular function in the rate. Br. J. Pharmacol. 56:93-99 (1976).
-
(1976)
Br. J. Pharmacol.
, vol.56
, pp. 93-99
-
-
Barber, H.E.1
Calvey, T.N.2
Muir, K.T.3
Taylor, K.4
-
23
-
-
0022499737
-
Clinical pharmacokinetics of cholinesterase inhibitors
-
S.-M. Aquilonius and P. Hartvig. Clinical pharmacokinetics of cholinesterase inhibitors. Clin. Pharmacokin. 11:236-249 (1986).
-
(1986)
Clin. Pharmacokin.
, vol.11
, pp. 236-249
-
-
Aquilonius, S.-M.1
Hartvig, P.2
-
24
-
-
0023205130
-
Determination of ambenonium chloride in serum by reversed-phase ion-pair liquid chromatography
-
C. Tharasse-Bloch, C. Chabenat, P. Boucly, and J. Marchand. Determination of ambenonium chloride in serum by reversed-phase ion-pair liquid chromatography. J. Chromatog. 421:407-411 (1987).
-
(1987)
J. Chromatog.
, vol.421
, pp. 407-411
-
-
Tharasse-Bloch, C.1
Chabenat, C.2
Boucly, P.3
Marchand, J.4
-
25
-
-
0024211177
-
Determination of ambenonium in biological samples by reversed-phase ion-pair liquid chromatography
-
K. Yamamoto, Y. Kohda, Y. Saitoh, and F. Nakagawa. Determination of ambenonium in biological samples by reversed-phase ion-pair liquid chromatography. J. Chromatog. 433:167-176 (1988).
-
(1988)
J. Chromatog.
, vol.433
, pp. 167-176
-
-
Yamamoto, K.1
Kohda, Y.2
Saitoh, Y.3
Nakagawa, F.4
-
26
-
-
0024841934
-
Sensitive determination of ambenonium chloride in serum from patients with myasthenia gravis using ion-exchange resin extraction and reversed-phase ion-pair chromatography
-
K. Ohtsubo, S. Higuchi, and T. Aoyama. Sensitive determination of ambenonium chloride in serum from patients with myasthenia gravis using ion-exchange resin extraction and reversed-phase ion-pair chromatography. J. Chromatog. 496:397-406 (1989).
-
(1989)
J. Chromatog.
, vol.496
, pp. 397-406
-
-
Ohtsubo, K.1
Higuchi, S.2
Aoyama, T.3
-
27
-
-
0027164224
-
Sensitive determination of ambenonium in plasma using inhibitory activity to acetylcholinesterase
-
K. Yamamoto, Y. Sawada, and T. Iga. Sensitive determination of ambenonium in plasma using inhibitory activity to acetylcholinesterase. Biol. Pharm. Bull. 16:280-283 (1993).
-
(1993)
Biol. Pharm. Bull.
, vol.16
, pp. 280-283
-
-
Yamamoto, K.1
Sawada, Y.2
Iga, T.3
-
28
-
-
0025995682
-
Pharmacokinetics of ambenonium. A reversible cholinesterase inhibitor, in rats
-
K. Yamamoto, Y. Kohda, Y. Sawada, and T. Iga. Pharmacokinetics of ambenonium. a reversible cholinesterase inhibitor, in rats. Biopharm. Drug Dispos. 12:613-625 (1991).
-
(1991)
Biopharm. Drug Dispos.
, vol.12
, pp. 613-625
-
-
Yamamoto, K.1
Kohda, Y.2
Sawada, Y.3
Iga, T.4
-
29
-
-
0024502367
-
Pharmacokinetics of ambenonium chloride in dogs after intravenous and oral administration
-
C. Tharasse-Bloch, C. Chabenat, P. Boucly, F. Boismare, and J. Marchand. Pharmacokinetics of ambenonium chloride in dogs after intravenous and oral administration. Arzeneim. Forsch. 39:257-258 (1989).
-
(1989)
Arzeneim. Forsch.
, vol.39
, pp. 257-258
-
-
Tharasse-Bloch, C.1
Chabenat, C.2
Boucly, P.3
Boismare, F.4
Marchand, J.5
-
30
-
-
0026335665
-
Pharmacokinetic studies of ambenonium chloride in patients with myasthenia gravis
-
C. Tharasse-Bloch, C. Chabenat, P. Boucly, J. Marchand, D. Elkharrat, C. Boucly-Goester, and P. Gajdos. Pharmacokinetic studies of ambenonium chloride in patients with myasthenia gravis. Eur. J. Drug Metab. Pharmacokin. 16:299-303 (1991).
-
(1991)
Eur. J. Drug Metab. Pharmacokin.
, vol.16
, pp. 299-303
-
-
Tharasse-Bloch, C.1
Chabenat, C.2
Boucly, P.3
Marchand, J.4
Elkharrat, D.5
Boucly-Goester, C.6
Gajdos, P.7
-
31
-
-
0026561449
-
Influence of food on serum ambenonium concentration in patients with myasthenia gravis
-
K. Ohtsubo, N. Fujii, S. Higuchi, T. Aoyama, I. Goto, and T. Tatsuhara. Influence of food on serum ambenonium concentration in patients with myasthenia gravis. Eur. J. Clin. Pharmacol. 42:371-374 (1992).
-
(1992)
Eur. J. Clin. Pharmacol.
, vol.42
, pp. 371-374
-
-
Ohtsubo, K.1
Fujii, N.2
Higuchi, S.3
Aoyama, T.4
Goto, I.5
Tatsuhara, T.6
-
32
-
-
0017757409
-
Plasma concentration of pyridostigmine and effects in myasthenia gravis
-
K. Chan and T. N. Calvey. Plasma concentration of pyridostigmine and effects in myasthenia gravis. Clin. Pharmacol. Ther. 22:596-601 (1978).
-
(1978)
Clin. Pharmacol. Ther.
, vol.22
, pp. 596-601
-
-
Chan, K.1
Calvey, T.N.2
-
33
-
-
0019825483
-
The relationship of plasma levels of pyridostigmine to clinical effect in patients with myasthenia gravis
-
S. C. Davison, N. M. Hyman, A. Dehghan, and K. Chan. The relationship of plasma levels of pyridostigmine to clinical effect in patients with myasthenia gravis. J. Neurol. Neurosurg. Psychiat. 44:1141-1145 (1981).
-
(1981)
J. Neurol. Neurosurg. Psychiat.
, vol.44
, pp. 1141-1145
-
-
Davison, S.C.1
Hyman, N.M.2
Dehghan, A.3
Chan, K.4
-
34
-
-
0020620749
-
Clinical pharmacology of pyridostigmine and neostigmine in patients with myasthenia gravis
-
S.-M. Aquilonius, S.-Å. Eckernäs, P. Hartvig, B. Lindström, and P. O. Osterman. Clinical pharmacology of pyridostigmine and neostigmine in patients with myasthenia gravis. J. Neurol. Neurosurg. Psychiat. 46:929-935 (1983).
-
(1983)
J. Neurol. Neurosurg. Psychiat.
, vol.46
, pp. 929-935
-
-
Aquilonius, S.-M.1
Eckernäs, S.-Å.2
Hartvig, P.3
Lindström, B.4
Osterman, P.O.5
-
35
-
-
0028074262
-
Appearance of tolerance in increase of contractile muscle tension by ambenonium in rats
-
K. Yamamoto, Y. Sawada, and T. Iga. Appearance of tolerance in increase of contractile muscle tension by ambenonium in rats. Biol. Pharm. Bull. 17:944-947 (1994).
-
(1994)
Biol. Pharm. Bull.
, vol.17
, pp. 944-947
-
-
Yamamoto, K.1
Sawada, Y.2
Iga, T.3
-
36
-
-
0016748089
-
A comparison of the effect of cholinesterase inhibitors on end-plate current and on cholinesterase activity in frog muscle
-
M. Kordas, M. Brzin, and Z. A. Majcen. A comparison of the effect of cholinesterase inhibitors on end-plate current and on cholinesterase activity in frog muscle. Neuropharmacoiogy 14:791-800 (1975).
-
(1975)
Neuropharmacoiogy
, vol.14
, pp. 791-800
-
-
Kordas, M.1
Brzin, M.2
Majcen, Z.A.3
-
37
-
-
0022518158
-
Multiple interactions of anticholinesterases with Aplysia acetylcholine responses
-
N. T. Slater, M. Filbert, and D. O. Carpenter. Multiple interactions of anticholinesterases with Aplysia acetylcholine responses. Bruin Res. 375:407-412 (1986).
-
(1986)
Bruin Res.
, vol.375
, pp. 407-412
-
-
Slater, N.T.1
Filbert, M.2
Carpenter, D.O.3
-
38
-
-
0025232496
-
Comparison of anticholesterases and their effects on acetylcholine-activated ion channels
-
R. E. Wachtel. Comparison of anticholesterases and their effects on acetylcholine-activated ion channels. Anesthesiology 72:496-503 (1990).
-
(1990)
Anesthesiology
, vol.72
, pp. 496-503
-
-
Wachtel, R.E.1
-
39
-
-
0021336306
-
The nature of the interactions of pyridostigmine with the nicotinic acetylcholine receptor-ionic channel complex. I. Agonist, desensitizing, and binding properties
-
G. J. Pascuzzo, A. Akaike, M. A. Maleque, K. P. Shaw, R. S. Aronstam, D. L. Rickett, and E. X. Albuquerque. The nature of the interactions of pyridostigmine with the nicotinic acetylcholine receptor-ionic channel complex. I. Agonist, desensitizing, and binding properties. Mol. Pharmacol. 25:92-101 (1984).
-
(1984)
Mol. Pharmacol.
, vol.25
, pp. 92-101
-
-
Pascuzzo, G.J.1
Akaike, A.2
Maleque, M.A.3
Shaw, K.P.4
Aronstam, R.S.5
Rickett, D.L.6
Albuquerque, E.X.7
-
40
-
-
0019311571
-
Reversed-phase, ion-pair liquid chromatography of quaternary ammonium compounds. Determination of pyridostigmine, neostigmine and edrophonium in biological fluids
-
M. G. M. De Ruyter and R. Cronnelly. Reversed-phase, ion-pair liquid chromatography of quaternary ammonium compounds. Determination of pyridostigmine, neostigmine and edrophonium in biological fluids. J. Chromatog. 183:193-201 (1980).
-
(1980)
J. Chromatog.
, vol.183
, pp. 193-201
-
-
De Ruyter, M.G.M.1
Cronnelly, R.2
-
42
-
-
0021077291
-
A nonlinear least squares program based on differential equations, MULTI(RUNGE), for microcomputers
-
K. Yamaoka and T. Nakagawa. A nonlinear least squares program based on differential equations, MULTI(RUNGE), for microcomputers. J. Pharmacobiodyn. 6:595-606 (1983).
-
(1983)
J. Pharmacobiodyn.
, vol.6
, pp. 595-606
-
-
Yamaoka, K.1
Nakagawa, T.2
-
43
-
-
0016087979
-
Affinity of myasthenia drugs to acetylcholinesterase and acetylcholine receptor
-
S. A. Seifert and M. E. Eldefrawi. Affinity of myasthenia drugs to acetylcholinesterase and acetylcholine receptor. Biochem. Med. 10:258-265 (1974).
-
(1974)
Biochem. Med.
, vol.10
, pp. 258-265
-
-
Seifert, S.A.1
Eldefrawi, M.E.2
-
44
-
-
0027092277
-
Ambenonium is a rapidly reversible noncovalent inhibitor of acetylcholinesterase, with one of the highest known affinities
-
A. S. Hodge, D. R. Humphrey, and T. L. Rosenbery. Ambenonium is a rapidly reversible noncovalent inhibitor of acetylcholinesterase, with one of the highest known affinities. Mol. Pharmacol. 41:937-942 (1992).
-
(1992)
Mol. Pharmacol.
, vol.41
, pp. 937-942
-
-
Hodge, A.S.1
Humphrey, D.R.2
Rosenbery, T.L.3
-
45
-
-
0024474872
-
Pancuronium, gallamine, and d-tubocurarine compared: Is speed of onset inversely related to drug potency?
-
A. F. Kopman. Pancuronium, gallamine, and d-tubocurarine compared: Is speed of onset inversely related to drug potency? Anesthesiology 70:915-920 (1989).
-
(1989)
Anesthesiology
, vol.70
, pp. 915-920
-
-
Kopman, A.F.1
-
46
-
-
0026317834
-
A kinetic-dynamic model to explain the relationship between high potency and slow onset time for neuromuscular blocking drugs
-
F. Donati and C. Meistelman. A kinetic-dynamic model to explain the relationship between high potency and slow onset time for neuromuscular blocking drugs. J. Pharmacokin. Biopharm. 19:537-552 (1991).
-
(1991)
J. Pharmacokin. Biopharm.
, vol.19
, pp. 537-552
-
-
Donati, F.1
Meistelman, C.2
-
47
-
-
0026708529
-
Iontophoretic study of speed of action of various muscle relaxants
-
J. C. L. Min, I. Bekavac, M. I. Glavinovic, F. Donati, and D. R. Bevan. Iontophoretic study of speed of action of various muscle relaxants. Anesthesiology 77:351-356 (1992).
-
(1992)
Anesthesiology
, vol.77
, pp. 351-356
-
-
Min, J.C.L.1
Bekavac, I.2
Glavinovic, M.I.3
Donati, F.4
Bevan, D.R.5
-
48
-
-
0027486889
-
Speed of action of various muscle relaxants at the neuromuscular junction binding vs. buffering hypothesis
-
M. I. Glavinovic, J. C. L. Min, L. Kapural, F. Donati, and D. R. Bevan. Speed of action of various muscle relaxants at the neuromuscular junction binding vs. buffering hypothesis. J. Pharmacol. Exp. Ther. 265:1181-1186 (1992).
-
(1992)
J. Pharmacol. Exp. Ther.
, vol.265
, pp. 1181-1186
-
-
Glavinovic, M.I.1
Min, J.C.L.2
Kapural, L.3
Donati, F.4
Bevan, D.R.5
-
49
-
-
0021947834
-
Self-cancellation of drug properties as a mode of organ selectivity: The antimuscarinic effects of ambenonium
-
T. P. Kenakin and D. Beek. Self-cancellation of drug properties as a mode of organ selectivity: The antimuscarinic effects of ambenonium. J. Pharmacol. Exp. Ther. 732-740 (1985).
-
(1985)
J. Pharmacol. Exp. Ther.
, pp. 732-740
-
-
Kenakin, T.P.1
Beek, D.2
-
50
-
-
0018651796
-
Inhibitory effects of cholinergic agents on the release of transmitter at the frog neuromuscular junction
-
C. J. Duncan and S. J. Publicover. Inhibitory effects of cholinergic agents on the release of transmitter at the frog neuromuscular junction. J. Physiol. 294:91-103 (1979).
-
(1979)
J. Physiol.
, vol.294
, pp. 91-103
-
-
Duncan, C.J.1
Publicover, S.J.2
-
51
-
-
0023608121
-
Effect of pyridostigmine on tetanic contracture of innervated and denervated rat skeletal muscle
-
R. J. Anderson. Effect of pyridostigmine on tetanic contracture of innervated and denervated rat skeletal muscle. Neurotoxicology 8:553-560 (1987).
-
(1987)
Neurotoxicology
, vol.8
, pp. 553-560
-
-
Anderson, R.J.1
-
52
-
-
0019961662
-
Inhibition of human motor endplate cholinesterase by anticholinesterase compounds
-
M. Fujii and T. Namba. Inhibition of human motor endplate cholinesterase by anticholinesterase compounds. Acta Med. Okayama 36:229-232 (1982).
-
(1982)
Acta Med. Okayama
, vol.36
, pp. 229-232
-
-
Fujii, M.1
Namba, T.2
-
53
-
-
0022129536
-
Kinetics of cocaine distribution, elimination, and chronotropic effects
-
M. J. Chow, J. J. Ambre, T. I. Ruo, A. J. Atkinson, D. J. Bowsher, and M. W. Fischman. Kinetics of cocaine distribution, elimination, and chronotropic effects. Clin. Pharmacol. Ther. 38:318-324 (1985).
-
(1985)
Clin. Pharmacol. Ther.
, vol.38
, pp. 318-324
-
-
Chow, M.J.1
Ambre, J.J.2
Ruo, T.I.3
Atkinson, A.J.4
Bowsher, D.J.5
Fischman, M.W.6
-
55
-
-
0021954756
-
Acute tolerance to furosemide diuresis in humans. Pharmacokinetic-pharmacodynamic modeling
-
M. M. Hammarlund, B. O. Odlind, and L. K. Paalzow. Acute tolerance to furosemide diuresis in humans. Pharmacokinetic-pharmacodynamic modeling. J. Pharmacol. Exp. Ther. 233:447-453 (1985).
-
(1985)
J. Pharmacol. Exp. Ther.
, vol.233
, pp. 447-453
-
-
Hammarlund, M.M.1
Odlind, B.O.2
Paalzow, L.K.3
-
56
-
-
0026389663
-
Reversal of neuromuscular blockade in humans by neostigmine and edrophonium: A mathematical model
-
D. Verotta, J. Kitts, R. Rodriguez, J. Coldwell, R. D. Miller, and L. B. Sheiner. Reversal of neuromuscular blockade in humans by neostigmine and edrophonium: A mathematical model. J. Pharmacokin. Biopharm. 19:713-729 (1991).
-
(1991)
J. Pharmacokin. Biopharm.
, vol.19
, pp. 713-729
-
-
Verotta, D.1
Kitts, J.2
Rodriguez, R.3
Coldwell, J.4
Miller, R.D.5
Sheiner, L.B.6
-
57
-
-
0019509189
-
Pharmacokinetics of edrophonium and neostigmine when antagonizing d-tubocurarine neuromuscular blockade in man
-
R. B. Morris, R. Cronnelly, R. D. Miller, D. R. Stanski, and M. R. Fahey. Pharmacokinetics of edrophonium and neostigmine when antagonizing d-tubocurarine neuromuscular blockade in man. Anesthesiology 54:399-402 (1981).
-
(1981)
Anesthesiology
, vol.54
, pp. 399-402
-
-
Morris, R.B.1
Cronnelly, R.2
Miller, R.D.3
Stanski, D.R.4
Fahey, M.R.5
|