-
1
-
-
3142605490
-
-
Chugai Pharm. Co., Ltd.. EP 184112, JP 86267548, JP 86267550
-
Kubodera, N., Miyamoto, K., Ochi, K., Matsunaga, I., Murayama, E. (Chugai Pharm. Co., Ltd.). Novel vitamin D derive, and process for producing the same. EP 184112, JP 86267548, JP 86267550.
-
Novel Vitamin D Derive, and Process for Producing the Same
-
-
Kubodera, N.1
Miyamoto, K.2
Ochi, K.3
Matsunaga, I.4
Murayama, E.5
-
4
-
-
2742556510
-
Active vitamin D analogs. Important and various roles by medicinal chemists during the course of development of promising candidates as useful medicines
-
Kubodera, N. Active vitamin D analogs. Important and various roles by medicinal chemists during the course of development of promising candidates as useful medicines. Jpn J Org Chem 1996, 54: 139-45.
-
(1996)
Jpn J Org Chem
, vol.54
, pp. 139-145
-
-
Kubodera, N.1
-
5
-
-
3142533114
-
-
Chugai Pharm. Co., Ltd.. WO 9312083
-
Kato, M., Mikami, T., Ochi, K., Watanabe, H., Kubodera, N. (Chugai Pharm. Co., Ltd.). 22-Oxacalciferol deriv. and production thereof. WO 9312083.
-
22-Oxacalciferol Deriv. and Production Thereof
-
-
Kato, M.1
Mikami, T.2
Ochi, K.3
Watanabe, H.4
Kubodera, N.5
-
8
-
-
0024510484
-
The role of the vitamin D endocrine system in health and disease
-
Reichel, H., Koeffler, H.P., Norman, A.W. The role of the vitamin D endocrine system in health and disease. New Engl J Med 1989, 320: 980-91.
-
(1989)
New Engl J Med
, vol.320
, pp. 980-991
-
-
Reichel, H.1
Koeffler, H.P.2
Norman, A.W.3
-
10
-
-
0017899114
-
1,25-Dihydroxycholecalciferol effects in chronic dialysis: A double-blind controlled study
-
Berl, T., Berns, A.S., Huffler, W.E., Hammill, A.C., Alfrey, A.C., Arnaud, C.D., Shrier, R.W. 1,25-Dihydroxycholecalciferol effects in chronic dialysis: A double-blind controlled study. Ann Intern Med 1978, 88: 774-80.
-
(1978)
Ann Intern Med
, vol.88
, pp. 774-780
-
-
Berl, T.1
Berns, A.S.2
Huffler, W.E.3
Hammill, A.C.4
Alfrey, A.C.5
Arnaud, C.D.6
Shrier, R.W.7
-
11
-
-
0023240081
-
"High-dose" calcitriol for control of renal osteodystrophy in children on CAPD
-
Salusky, I.B., Fine, R.S., Kangarloo, H., Gold, R., Paunier, L., Goodman, W.G., Brill, J.E., Gilli, G., Slatopolsky, E., Coburn, J.W. "High-dose" calcitriol for control of renal osteodystrophy in children on CAPD. Kidney Int 1987, 32: 89-95.
-
(1987)
Kidney Int
, vol.32
, pp. 89-95
-
-
Salusky, I.B.1
Fine, R.S.2
Kangarloo, H.3
Gold, R.4
Paunier, L.5
Goodman, W.G.6
Brill, J.E.7
Gilli, G.8
Slatopolsky, E.9
Coburn, J.W.10
-
12
-
-
0023544729
-
Synthetic analogues of vitamin D3 with an oxygen atom in the side chain skeleton
-
Abe, J., Morikawa, M., Miyamoto, K., Kaiho, S., Fukushima, M., Miyaura, C., Abe, E., Suda, T., Nishii, Y. Synthetic analogues of vitamin D3 with an oxygen atom in the side chain skeleton. FEBS Lett 1987, 226: 58-62
-
(1987)
FEBS Lett
, vol.226
, pp. 58-62
-
-
Abe, J.1
Morikawa, M.2
Miyamoto, K.3
Kaiho, S.4
Fukushima, M.5
Miyaura, C.6
Abe, E.7
Suda, T.8
Nishii, Y.9
-
13
-
-
0027251444
-
3 analogue with antiangiogenic action
-
3 analogue with antiangiogenic action. Drug News Perspect 1993, 6: 157-62.
-
(1993)
Drug News Perspect
, vol.6
, pp. 157-162
-
-
Oikawa, T.1
Shimamura, M.2
Ashino, H.3
Morita, I.4
Murota, S.5
Abe, J.6
Nishii, Y.7
Tominaga, T.8
-
14
-
-
0024555109
-
3, is a potent modulator of in vivo immunoregulating activity without inducing hypercalcemia in mice
-
3, is a potent modulator of in vivo immunoregulating activity without inducing hypercalcemia in mice. Endocrinology 1989, 124: 2645-7.
-
(1989)
Endocrinology
, vol.124
, pp. 2645-2647
-
-
Abe, J.1
Takita, Y.2
Nakano, T.3
Miyaura, C.4
Suda, T.5
Nishii, Y.6
-
15
-
-
0025925343
-
3, inhibits the growth of human breast cancer in vitro and in vivo with-out causing hypercalcemia
-
3, inhibits the growth of human breast cancer in vitro and in vivo with-out causing hypercalcemia. Endocrinology 1991, 129: 832-7.
-
(1991)
Endocrinology
, vol.129
, pp. 832-837
-
-
Abe, J.1
Nakano, T.2
Nishii, Y.3
Matsumoto, T.4
Ogata, E.5
Ikeda, K.6
-
16
-
-
0029665053
-
3 on the proliferation of pancreatic cancer cell lines
-
3 on the proliferation of pancreatic cancer cell lines. Gastroenterology 1996, 110: 1605-13.
-
(1996)
Gastroenterology
, vol.110
, pp. 1605-1613
-
-
Kawa, S.1
Yoshizawa, K.2
Tokoo, M.3
Imai, H.4
Oguchi, H.5
Kiyosawa, K.6
Homma, T.7
Nikaido, T.8
Furihata, K.9
-
18
-
-
0027276092
-
Antitumor effect of 22-oxa-calcitriol, a noncalcemic analogue of calcitriol, in athymic mice implanted with human breast carcinoma and its synergism with tamoxifen
-
Abe-Hashimoto, J., Kikuchi, T., Matsumoto, T., Nishii, Y., Ogata, E., Ikeda, K. Antitumor effect of 22-oxa-calcitriol, a noncalcemic analogue of calcitriol, in athymic mice implanted with human breast carcinoma and its synergism with tamoxifen. Cancer Res 1993, 53: 2534-7.
-
(1993)
Cancer Res
, vol.53
, pp. 2534-2537
-
-
Abe-Hashimoto, J.1
Kikuchi, T.2
Matsumoto, T.3
Nishii, Y.4
Ogata, E.5
Ikeda, K.6
-
19
-
-
0026234680
-
3, a potent angiogenesis inhibitor, on rat mammary tumors induced by 7,12-dimethylbenz[a]anthracene
-
3, a potent angiogenesis inhibitor, on rat mammary tumors induced by 7,12-dimethylbenz[a]anthracene. Anti-Cancer Drugs 1991, 2: 475-80.
-
(1991)
Anti-Cancer Drugs
, vol.2
, pp. 475-480
-
-
Oikawa, T.1
Yoshida, Y.2
Shimamura, M.3
Ashino-Fuse, H.4
Iwaguchi, T.5
Tominaga, T.6
-
20
-
-
0029896415
-
3 (OCT) as a single agent or combined therapy with aromatase inhibitor (CGS 16949A) on 7,12-dimethylbenz[a]anthracene-induced rat mammary tumors
-
3 (OCT) as a single agent or combined therapy with aromatase inhibitor (CGS 16949A) on 7,12-dimethylbenz[a]anthracene-induced rat mammary tumors. Int J Oncol 1996, 9: 79-82.
-
(1996)
Int J Oncol
, vol.9
, pp. 79-82
-
-
Andoh, T.1
Lino, Y.2
-
21
-
-
0025148520
-
New active analogues of vitamin D with low calcemic action
-
Brown, A.J., Finch, J.L., Lopez-Hilker, S., Dusso, A., Ritter, C., Pernalette, N., Slatopolsky, E. New active analogues of vitamin D with low calcemic action. Kidney Int 1990, 38(Suppl. 29): S22-7.
-
(1990)
Kidney Int
, vol.38
, Issue.29 SUPPL.
-
-
Brown, A.J.1
Finch, J.L.2
Lopez-Hilker, S.3
Dusso, A.4
Ritter, C.5
Pernalette, N.6
Slatopolsky, E.7
-
22
-
-
0024435236
-
The non-catcemicanalog of vitamin D., 22-oxacalcitriol, suppresses parathyroid hormone synthesis and secretion
-
Brown, A.J., Ritter, C.R., Finch, J.L., Morrissey, J., Martin, K.J., Muramaya, E., Nishii, S., Slatopolsky, E. The non-catcemicanalog of vitamin D., 22-oxacalcitriol, suppresses parathyroid hormone synthesis and secretion. J Clin Invest 1989, 27: 728-32.
-
(1989)
J Clin Invest
, vol.27
, pp. 728-732
-
-
Brown, A.J.1
Ritter, C.R.2
Finch, J.L.3
Morrissey, J.4
Martin, K.J.5
Muramaya, E.6
Nishii, S.7
Slatopolsky, E.8
-
23
-
-
0025854980
-
Regulation of parathyroid hormone synthesis in chronic renal failure in rats
-
Fukagawa, M., Kaname, S.Y., Igarashi, T., Ogata, E., Kurokawa, K. Regulation of parathyroid hormone synthesis in chronic renal failure in rats. Kidney Int 1991, 39: 874-81.
-
(1991)
Kidney Int
, vol.39
, pp. 874-881
-
-
Fukagawa, M.1
Kaname, S.Y.2
Igarashi, T.3
Ogata, E.4
Kurokawa, K.5
-
24
-
-
0027131712
-
Effects of calcitriol, 22-oxacalcitriol, and calcipotriot on serum calcium parathyroid hormone gene expression
-
Naveh-Many, T., Silver, J. Effects of calcitriol, 22-oxacalcitriol, and calcipotriot on serum calcium parathyroid hormone gene expression. Endocrinology 1993, 133: 2724-8.
-
(1993)
Endocrinology
, vol.133
, pp. 2724-2728
-
-
Naveh-Many, T.1
Silver, J.2
-
25
-
-
0000611588
-
Effect of intravenous 22-oxacalcitriol (OCT) and calcitriol on secondary hyperparathyroidism in dogs with chronic renal failure (CRF)
-
Takahashi, S., Furuichi, T., Yorozu, K., Aso, Y., Kubodera, N., Slatopolsky, E. Effect of intravenous 22-oxacalcitriol (OCT) and calcitriol on secondary hyperparathyroidism in dogs with chronic renal failure (CRF). J Amer Soc Nephrol 1994, 5(3): 890.
-
(1994)
J Amer Soc Nephrol
, vol.5
, Issue.3
, pp. 890
-
-
Takahashi, S.1
Furuichi, T.2
Yorozu, K.3
Aso, Y.4
Kubodera, N.5
Slatopolsky, E.6
-
26
-
-
0011801886
-
3 (OCT) for the treatment of secondary hyperparathyroidism (2° HPT) in chronic renal failure (CRF) rats
-
3 (OCT) for the treatment of secondary hyperparathyroidism (2° HPT) in chronic renal failure (CRF) rats. J Amer Soc Nephrol 1994, 5(3): 857.
-
(1994)
J Amer Soc Nephrol
, vol.5
, Issue.3
, pp. 857
-
-
Tanaka, M.1
Hara, T.2
Imaito, O.3
Matuoka, F.4
Satoh, T.5
Owada, S.6
Isida, M.7
-
27
-
-
0029079766
-
22.Oxacalcitriol does not interfere with parathyroid hormone-induced phosphaturia or cyclic-AMP excretion
-
Friedlaender, M.M., Yagil, Y., Wald, H., Popovtzer, M.M. 22.Oxacalcitriol does not interfere with parathyroid hormone-induced phosphaturia or cyclic-AMP excretion. Bone 1995, 17: 301-6.
-
(1995)
Bone
, vol.17
, pp. 301-306
-
-
Friedlaender, M.M.1
Yagil, Y.2
Wald, H.3
Popovtzer, M.M.4
-
29
-
-
85086288323
-
3 and a new analogue, 22-oxacalcitriol modulate proliferation and interleukin-8 secretion in normal human keratinocytes
-
Abst 357
-
3 and a new analogue, 22-oxacalcitriol modulate proliferation and interleukin-8 secretion in normal human keratinocytes. J Invest Dermatol 1996, 106(4): Abst 357.
-
(1996)
J Invest Dermatol
, vol.106
, Issue.4
-
-
Koizumi, H.1
Kaplana, A.2
Shimizu, T.3
Ohkawara, A.4
-
31
-
-
0026657538
-
3, stimulates the production of prostacyclin by vascular tissues
-
3, stimulates the production of prostacyclin by vascular tissues. Life Sci 1992, 51: 1105-12.
-
(1992)
Life Sci
, vol.51
, pp. 1105-1112
-
-
Inoue, M.1
Wakasugi, M.2
Wakao, R.3
Gan, N.4
Tawata, M.5
Nishii, Y.6
Onaya, T.7
-
32
-
-
0028934370
-
Intracellular multiplication of Legionella pneumophilia in HL-60 cells functionally differentiated in response to 22-oxacalcitriol
-
Matsuzaki, M., Shimamoto, Y., Watanabe, M., Kukita, A., Yoshida, S., Tadano, J. Intracellular multiplication of Legionella pneumophilia in HL-60 cells functionally differentiated in response to 22-oxacalcitriol. J Leukocyte Biol 1995, 57: 574-80.
-
(1995)
J Leukocyte Biol
, vol.57
, pp. 574-580
-
-
Matsuzaki, M.1
Shimamoto, Y.2
Watanabe, M.3
Kukita, A.4
Yoshida, S.5
Tadano, J.6
-
35
-
-
85086290493
-
3, significantly increases bone mass in ovariectomizedrats
-
Abst 440
-
3, significantly increases bone mass in ovariectomizedrats. Bone 1995,16(1, Suppl.): Abst 440.
-
(1995)
Bone
, vol.16
, Issue.1 SUPPL.
-
-
Kiriyama, T.1
Fujiyama, K.2
Yokoyama, N.3
Nagataki, S.4
-
36
-
-
15844385076
-
In vitro metabolism of the vitamin D analog, 22-oxacalcitriol, usingcultured osteosarcoma, hepatoma, and keratinocyte cell lines
-
Masuda, S., Byford, V., Kremer, R., Makin, H.L.J., Kubodera, N., Nishii, Y., Okazaki, A., Okano, T., Kobayashi, T., Jones, G. In vitro metabolism of the vitamin D analog, 22-oxacalcitriol, usingcultured osteosarcoma, hepatoma, and keratinocyte cell lines. J Biol Chem 1996, 271: 8700-8.
-
(1996)
J Biol Chem
, vol.271
, pp. 8700-8708
-
-
Masuda, S.1
Byford, V.2
Kremer, R.3
Makin, H.L.J.4
Kubodera, N.5
Nishii, Y.6
Okazaki, A.7
Okano, T.8
Kobayashi, T.9
Jones, G.10
-
38
-
-
0027137195
-
Differential catabolism of 22-oxacalcitriol and 1,25-dihydroxyvitamin D3 by normal human peripheral monocytes
-
Kamimura, S., Gallieni, M., Kubodera, N., Nishii, S., Brown, A.J., Slatopolsky, E., Dusso, A. Differential catabolism of 22-oxacalcitriol and 1,25-dihydroxyvitamin D3 by normal human peripheral monocytes. Endocrinology 1993, 133: 2719-23.
-
(1993)
Endocrinology
, vol.133
, pp. 2719-2723
-
-
Kamimura, S.1
Gallieni, M.2
Kubodera, N.3
Nishii, S.4
Brown, A.J.5
Slatopolsky, E.6
Dusso, A.7
-
39
-
-
0028281814
-
3, in rats
-
3, in rats. J Biochem 1994, 115: 373-80.
-
(1994)
J Biochem
, vol.115
, pp. 373-380
-
-
Kobayashi, T.1
Tsugawa, N.2
Okano, T.3
Masuda, S.4
Takeuchi, A.5
Kubodera, N.6
Nishii, Y.7
-
40
-
-
0028987358
-
3 having valuable clinical potency, in rat and human plasma
-
3 having valuable clinical potency, in rat and human plasma. Biol Pharm Bull 1995, 18: 382-7.
-
(1995)
Biol Pharm Bull
, vol.18
, pp. 382-387
-
-
Kobayashi, N.1
Shimada, K.2
Taki, H.3
Sakamoto, Y.4
Kamachi, S.5
-
41
-
-
0029757288
-
Effect of 22-oxacalcitriol on hyperparathyroidism of dialysis patients: Results of a preliminary study
-
Kurokawa, K., Akizawa, T., Suzuki, M., Akiba.T., Ogata, E., Slatopolsky, E. Effect of 22-oxacalcitriol on hyperparathyroidism of dialysis patients: Results of a preliminary study. Neph rol Dial Transplant 1996, 11 (Suppl. 3): 121-4.
-
(1996)
Neph Rol Dial Transplant
, vol.11
, Issue.3 SUPPL.
, pp. 121-124
-
-
Kurokawa, K.1
Akizawa, T.2
Suzuki, M.3
Akiba, T.4
Ogata, E.5
Slatopolsky, E.6
-
42
-
-
0003820162
-
-
Chugai Pharmaceutical Co., Ltd.
-
Chugai Pharmaceutical Co., Ltd. Annual Report 1996.
-
(1996)
Annual Report
-
-
|