Synthesis of anthraquinone-2-carboxylic acid derivatives as inhibitors of small intestinal motility

Chinese Pharmaceutical Journal

Volumn 48, Issue 4, 1996, Pages 313-320

  Kuo, Daih Huang ^a   Cheng, Juei Tang ^c   Tu, Yuan San ^b   Kuo, Sheng Chu ^b  

^a TAJEN INSTITUTE OF TECHNOLOGY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

anthraquinone 2 carboxamides; anthraquinone 2 carboxylates; intestinal motility; spasmolytic

Indexed keywords

ANTHRAQUINONE DERIVATIVE;

ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; DRUG ACTIVITY; DRUG SYNTHESIS; INTESTINE MOTILITY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RABBIT; REACTION ANALYSIS;

EID: 0030484464     PISSN: 10161015     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Bonnycastle, D. D. Cathartics and Laxatives. in Drill's Pharmacology in Medicine, 3rd ed.; Di Palma, J. R. Ed. McGraw-Hill: New York, 1965; p 747.
2. de Wite, P.; Lemli, L. The Metabolism of Anthranoid Laxatives. Hepatogastroenterology 1990, 37, 601-605.
3. Gaginella, T. S.; Base, P. Laxatives: An Update on Mechanism of Action. Life Sci. 1978, 23, 1001-1010.
4. Ellis, G. P.; Peel, M. V. [(1H-Tetrazol-5-yl)carbamoyl]Anthraquinone, -Xanthones and -Chromones. Ger. Offen. 1973, 249100 (C1. C07d, A61k).
5. Tanimoto, Y.; Uehara, M.; Takashima, M.; Itoh, M. Spectroscopic Studies on the Intramolecular Hydrogen Abstraction Reactions of n-Alkyl Anthraquinone-2-carboxylates. Bull. Chem. Soc. Jpn. 1988, 61, 3121-3127.