Constitutive biological activity of thymus-independent TCR-α-β+ intestinal intraepithelial lymphocytes in TCR-α(-/-) gene disruption mice

Immunology Letters

Volumn 54, Issue 1, 1996, Pages 53-57

  Neuhaus, Oliver ^a   Emoto, Masashi ^a,b   Kaufmann, Stefan H E ^a,b  

^a UNIVERSITY OF ULM   (Germany)

^b MAX PLANCK INSTITUTE FOR INFECTION BIOLOGY   (Germany)

Author keywords

cytolytic activity; intestinal intraepithelial lymphocytes; knockout mice; TCR + cells

Indexed keywords

T LYMPHOCYTE RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; CELL DIFFERENTIATION; CYTOTOXIC T LYMPHOCYTE; FLOW CYTOMETRY; INTESTINE LYMPHATIC TISSUE; MOUSE; MUTANT; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION; THYMUS; TRANSGENIC MOUSE;

ANIMALS; GENE DELETION; INTESTINAL MUCOSA; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; PHENOTYPE; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; T-LYMPHOCYTES; THYMUS GLAND;

EID: 0030483468     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-2478(96)02647-8     Document Type: Article

References (12)

1. [1] Chan, A.C., Irving, B.A. and Weiss, A. (1992) Curr. Opin. Immunol. 4, 246.
2. [2] Mombaerts, P., Clarke, A.R., Rudnicki, M.A., Iacomini, J., Itohara, S., Lafaille, J.J., Wang, L., Ichikawa, Y., Jaenisch, R., Hooper, M.L. and Tonegawa, S. (1992) Nature 360, 225.
3. [3] Kruisbeck, A.M. (1993) Curr. Opin. Immunol. 5, 227.
4. [4] Groettrup, M., Baron, A., Griffiths, G., Palacios, R. and von Boehmer, H. (1992) EMBO J. 11, 2735.
5. [5] Eichelberger, M., McMickle, A., Blackman, M., Mombaerts, P., Tonegawa S. and Doherty, P.C. (1995) J. Immunol. 154, 1569.
6. [6] Viney, J.L., Dianda, L., Roberts, S.J., Wen, L., Mallick, C.A., Hayday, A.C. and Owen, M.J. (1994) Proc. Natl. Acad. Sci. USA 91, 11 948.
7. [7] Viney, J., Philpott, K. and Owen, M. (1995) in: Advances in Mucosal Immunology. Part A (J. Mestecky, M.W. Russell, S. Jackson, S.M. Michalek, H. Tlaskalová-Hogenová and J. Šterzl, Eds.) Vol. 371, pp. 117-120, Plenum Press, New York.
8. [8] Kiyono, H. and McGhee, J.R. (1994) Mucosal Immunology: Intraepithelial Lymphocytes, Raven Press, New York.
9. [9] Mombaerts, P., Mizoguchi, E., Ljunggren, H.G., Iacomini, J., Ishikawa, H., Wang, L., Grusby, M.J., Glimcher, L.H., Winn, HJ., Bhan, A.K. and Tonegawa, S. (1994) Int. Immunol. 6, 1061.
10. [10] Neuhaus, O., Emoto, M., Blum, C., Yamamoto, S. and Kaufmann, S.H.E. (1995) Eur. J. Immunol. 25, 2332.
11. [11] Philpott, K.L., Viney, J.L., Kay, G., Rastan, S., Gardimer, E.M., Chae, S., Hayday, A.C. and Owen, M.J. (1992) Science 256, 1448.
12. [12] Mallick, C.A., Dudley, B.C., Viney, J.L., Owen, M.J. and Hayday, A.C. (1993) Cell 73, 513.