Influence of adjuvants on the induction of autoantibodies to the thyrotropin receptor

Autoimmunity

Volumn 24, Issue 4, 1996, Pages 205-215

  Seetharamalah, Gattadahallis S ^a   Fan, Ji Lao ^a   Patibandla, Sai A ^a   Prabhakar, Bellur S ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Autoimmunity; Bovine serum albumin; Complete Freund's adjuvant; Gerbu; Thyrotropin receptor; Titer Max; TSH binding inhibitory immunoglobulins

Indexed keywords

AUTOANTIBODY; BOVINE SERUM ALBUMIN; FREUND ADJUVANT; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN SUBCLASS; THYROTROPIN; THYROTROPIN RECEPTOR; THYROTROPIN RECEPTOR ANTIBODY;

ANIMAL EXPERIMENT; ANTIBODY TITER; ARTICLE; AUTOIMMUNITY; BLOOD DONOR; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNIZATION; MOUSE; NONHUMAN; PROTEIN INDUCTION;

EID: 0030482399     PISSN: 08916934     EISSN: None     Source Type: Journal    
DOI: 10.3109/08916939608994713     Document Type: Article

References (31)

1. Fan, J. L., Seetharamaiah, G. S., Desai, R. K., Dallas, J. S., Wagle, N. M., Prabhakar, B. S. Analysis of autoantibody reactivity in patients with Graves' disease using recombinant extracellular domain of the human thyrotropin receptor and synthetic peptides. Autoimmunity. 1993: 15: 285-291.
2. Wagle, N. M., Dallas, J. S., Seetharamaiah, G. S., Fan, J. L., Desai, R. K., Memar, O., Rajaraman, S., Prabhakar, B. S. Induction of hyperthyroxinemia in BALB/c but not in several other strains of mice. Autoimmunity 1994; 18: 103-112.
3. Rose, N. R., Twarog, F. J., Crowle, A. J. Murine thyroiditis: importance of adjuvant and mouse strain for the induction of thyroid lesions. J. Immnunol. 1971; 106: 698-704.
4. Patrick, J., Lindstrom, J. Autoimmune response to actylcholine receptor. Science 1973; 180 871-872.
5. Doherty, P., Simpson, E. Murine models of multipleselerosis. Nature 1982; 299: 106-107.
6. Tung, K. S., Teuscher, C., Smith, S. M., Ellis, L., Dufan, M. L. Factors that regulate the development of testicular autoimmune diseases. NY Acad Sci 1984; 438: 171-188.
7. Christadoss, P., Lennon, V. A., Kreo, C. J., Lambert, E. H., David, C. S. Genetic control of autoimmunity to actylcholinc receptors: Role of la molecules. Ann. NY Acad. Sci. 1981; 377: 258-276.
8. Freund, J. The mode of action of Immunologic adjuvants. Adv. Tubere Res. 1956; 7: 130-145.
9. Freund, J., Stern, E. R., Pisani, T. M. Isoallergic encephalomyclitis in guinea pigs after one injection of brain and mycobacteria in water-in-oil emulsion. J. Immuinol. 1947; 57: 179-194.
10. McMaster, P. R. B., Lerner 2nd E. M., Exum, E. D. The relationship of delayed hypersensitivity and circulating antibody to experimental allergic thyroditis in inbred guinea pigs. J Exp. Med 1961; 113:611-623.
11. Bennett, B., Check, I. J., Olsen, M. R., Hunter, R. L. A comparison of commercially available adjuvants for use in research. J Immunol. Med. 1992; 153: 31-40.
12. Grubhofer, N An adjuvant formulation based on N-actylglucosaminyl-N-acctylniuramyl-L-alanyl-D-isoglutamine with dimethyldioctadccylammonium chloride and zinc-L-prolinc complex as synergists. Immunol Lett. 1995; 44: 19-24.
13. Adam, A., Ciobaru, R., Ellouz, F., Petit, J. F., Lederer, E. Adjuvant activity of monomeric bacterial cell wall peptidoglycans. Biochem Biophys Res. Comm 1974; 56: 561-567.
14. Ellouz, F., Adam, A., Ciorbaru, R., Lederer, E. Minimal structural requirements for adjuvant acitivty of bacterial peptidoglycan derivatives. Biochem. Biophys. Res. Comm 1974; 59: 1317-1325.
15. Andronova, T., Ivanov, V. The structure and immunomodulating function of glucosaminylmuramyl peptides. Sov. Med Rev D Immunol. 1991; 4: 1-63.
16. Singh, K. P., Zaidi, S. I. A., Raisuddin, S., Saxcna, A. K , Murthy, R., Ray, P. K. Effect of zinc on immune functions and host resistance against infection and tumor challenge. Immunopharmacol. Immunotoxicol 1992; 14: 813-840.
17. Seetharamaiah, G. S., Desai, R. K., Dallas, J S., Tahara, K., Kohn, L. D., Prabhakar, B. S. Induction of TSH binding inhibitory immunoglobulins with the extracellular domain of human thyrotropin receptor produced using baculovirus expression system, Autoimmunity 1993; 14: 315-320.
18. Seetharamaiah, G. S., Kurosky, A., Desai, R. K., Dallas. J. S., Prabhakar, B. S. A recombinant extracellular domain of the thyrotropin (TSH) receptor binds TSH in the absence of membranes. Endocrinol. 1994; 134: 549-554.
19. Seetharamaiah, G. S., Wagle, N. M., Morris, J. C., Prabhakar, B. S. Generation and characterization of monoclonal antibodies to the human thyrotropin (TSH) receptor: Antibodies can bind to discrete conformational or linear epitopes and block TSH binding. Endocrinol. 1995; 136: 2817-2824.
20. Morris, J. C., Bergert, E. R., McCormick, D. J. Structure-function studies of the human thyrotropin receptor: inhibition of binding of labeled thyrotropin (TSH) by synthetic human thyrotropin receptor peptides. J Biol. Chem. 1993; 268: 10900-10905.
21. Dallas, J. S., Desai, R. K., Cunningham, S. J., Morris, J. C, Seetharamaiah, G. S., Wagle, N., Goldblum, R. M., Prabhakar, B. S. Thyrotropin (TSH) interacts with multiple discrete regions of the TSH receptors: polyclonal rabbit antibodies to one of more of these regions can inhibit TSH binding and function. Endocrinol 1994; 134: 1437-1445.
22. Southgate, K., Creagh, F., Teece, M., Kingswood, C., Rees-Smith, B. A receptor assay for the measurement of TSH receptor antibodies in unextracted serum. Clin Endocrinol. (Oxf) 1984; 20: 539-543.
23. Valensi, J. P. M., Clarson, J. R., Van Nest, G A. Systemic cytokine profiles in BALB/c mice immunized with trivalent influenza vaccine containing MF59 oil emulsion and other adjuvants. J. Immunol 1994, 153: 4029-4039.
24. Kalish, M. L., Check, I J., Hunter, R. L Murine IgG isotype responses to the Plsmodium cynomolgi circumsporozitc peptide (NAGG)5. I. Effects of carrier, copolymcr adjuvants, and lipopolysaccharide on isotype selection. J. Immunol 1991; 146. 3583-3590.
25. Bomford, R., Stapleton, M., Winsor, S., McKnight, A., Andronova, T. The control of antibody isotype response to recombinant human immunodeficiency virus gp 120 antigen by adjuvants. AIDS Res. and Human Retrovir 1992; 8: 1765-1771.
26. Wagle, N. M., Patibandla, S. A., Dallas, J. S., Morris, J. C., Prabhakar, B. S. Thyrotropin receptor specific antibodies in BALB/cJ mice with experimental hyperthyroxinemia show a restricted binding specificity and belong to the IgG1 subclass. Endocrinol. 1995; 136: 3461-3469.
27. Marion, S., Braun, J. M., Ropars, A., Kohn, L. D., Charreirc, J Induction of autoimmunity by immunization of mice with human thyrotropin receptor. Cellular Immunol. 1994; 158: 329-341.
28. Costagliola, S., Alcalde, L., Tonacchera, M., Ruf, J., Vassart, G., Ludgate, M. Induction of thyrotropin receptor (TSH-R) autoantibodies and thyroiditis in mice immunised with the Recombinant TSH-R. Boichem. Boiphys Res. Comm 1994; 199: 1027-1034.
29. Costagliola, S., Many, M. C., Stalmans-Falys, M., Tonacchera, M., Vassart, G., Ludgate, M. Recombinant thyrotropin receptor and the induction of autoimmune thyroid disease in BALB/c mice: A new animal model. Endocrinol 1994; 135: 2150-2159.
30. Carayanniotis, G., Huang, G. C., Nicholson, L. B., Scott, T., Allain, P., McGregor, A. M., Banga, J. P. Unaltered thyroid function in mice responding to a highly immunogenic thyrotropin receptor: implications for the establishment of a mouse model for Graves' disease Clin. Exp. Immunol 1995; 99: 294-302.
31. Vlase, H., Nakashima, M., Graves, P. N., Tomer, Y., Morris, J. C., Davies. T. F. Defining the major antibody epitopes on the human thyrotropin receptor in immunized mice: evidence for intramolecular epitope spreading. Endocrinol 1995; 136: 4415-4423.