Sex-dependent pharmacokinetics of indinavir in vivo and in vitro evidence

Drug Metabolism and Disposition

Volumn 24, Issue 12, 1996, Pages 1298-1306

  Lin, Jiunn H ^a   Chiba, Masato ^a   Chen, I Wu ^a   Nishime, Joy A ^a   Vastag, Kari J ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; CARBON 14; INDINAVIR;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DOG; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG METABOLISM; ENZYME ACTIVITY; FEMALE; INTRAVENOUS DRUG ADMINISTRATION; ISOTOPE LABELING; LIVER MICROSOME; MALE; MONKEY; NONHUMAN; PRIORITY JOURNAL; RAT; SEX DIFFERENCE; SPECIES DIFFERENCE;

ANIMALS; AREA UNDER CURVE; ARYL HYDROCARBON HYDROXYLASES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; DOGS; FEMALE; HIV PROTEASE INHIBITORS; HUMANS; INDINAVIR; INJECTIONS, INTRAVENOUS; MACACA MULATTA; MALE; MICROSOMES, LIVER; OXIDOREDUCTASES, N-DEMETHYLATING; RATS; RATS, SPRAGUE-DAWLEY; SEX CHARACTERISTICS; SPECIES SPECIFICITY;

ANIMALIA; CANIS FAMILIARIS; HUMAN IMMUNODEFICIENCY VIRUS;

EID: 0030482184     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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