Galanin positively modulates prolactin secretion in normal women

Journal of Endocrinological Investigation

Volumn 19, Issue 11, 1996, Pages 739-744

  Grottoli, S ^a   Arvat, E ^a   Gianotti, L ^a   Ramunni, J ^a   Di Vito, L ^a   Maccagno, B ^a   Ciccarelli, E ^a   Camanni, F ^a   Ghigo, E ^a,b  

^a UNIVERSITY OF TURIN   (Italy)

^b Divisione di Endocrinologia OIRM Torino   (Italy)

Author keywords

Arginine; Galanin; Metoclopramide; PRL; TRH

Indexed keywords

ARGININE; DOPAMINE RECEPTOR BLOCKING AGENT; GALANIN; METOCLOPRAMIDE; NEUROPEPTIDE; PROLACTIN; PROTIRELIN;

ADULT; AGITATION; AREA UNDER THE CURVE; ARTICLE; CLINICAL ARTICLE; DOPAMINE RECEPTOR BLOCKING; DOPAMINERGIC SYSTEM; DRUG EFFECT; FEMALE; FOLLICULAR PHASE; HUMAN; HUMAN EXPERIMENT; INTRAVENOUS DRUG ADMINISTRATION; NORMAL HUMAN; PROLACTIN RELEASE;

EID: 0030481563     PISSN: 03914097     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03347877     Document Type: Article

References (35)

1. Tatemoto K., Rokaeus A., Fornvall H., McDonald T.J., Mutt V. Galanin: a novel biologically active peptide from porcine intestine. FEBS Lett. 164: 124, 1983.
2. Bauer F.E., Venetikou M., Burrin J.M., Ginsberg L., MacKay D.J., Bloom S.R. Growth hormone release in man induced by galanin, a new hypothalamic peptide. Lancet 2: 192, 1986.
3. Skofitsch G., Jacobowitz D.M. Quantitative distribution of galanin-like immunoreactivity in the rat central nervous system. Peptides 7: 609, 1986.
4. Melander T., Hokfelt T., Rokaeus A. Distribution of galanin-like immunoreactivity in the rat central nervous system. J. Comp. Neurol. 248: 475, 1986.
5. Melander T., Hokfelt T., Rokaeus A., Cuello A.C., Oertel W.H., Verhofstad A., Goldstein M. Co-existence of galanin-like immunoreactivity with catecholamines, 5-hydroxytryptamine, GABA and neuropeptides in the rat CNS J. Neurosci. 6: 3640, 1986.
6. Niimi M., Takahara J., Sato M., Kawanishi K. Immunoistochemical identification of galanin and growth hormone-releasing factor-containing neurons projecting to the median eminence of the rat Neuroendocrinology 51: 572, 1990.
7. Merchenthaler I., Lopez F.J., Lennard D.E., NegroVilar A. Sexual differences in the distribution of neurons coexpressing galanin and luteinizing hormone-releasing hormone in the rat brain. Endocrinology 129: 1977, 1991.
8. Ottlecz A., Snyder G.D., McCann S.M. Regulatory role of galanin in the control of hypothalamic-anterior pituitary function Proc. Natl. Acad. Sci. 85: 9861, 1988.
9. Vrontakis M.E., Torsello A., Friesen H.G. Galanin. J. Endocrinol. Invest. 14: 785, 1991.
10. Wynick D., Smith D.M., Gathei M., Akinsanya K., Bhogal R., Purkiss P., Byfield P., Yanaihara N., Bloom S.R. Characterization of high-affinity galanin receptor in the rat anterior pituitary: absence of biological effect and reduced membrane binding of antagonist M15 differentiate it from the brain/gut receptor. Proc. Natl. Acad. Sci. 90: 4231, 1993.
11. Steel J.H., Gon G., O'Halloran D.J., Jones P.M., Yanaihara N., Ishikawa H., Bloom S.R., Polak J.M. Galanin and vasoactive intestinal polypeptide are colocalised with classical pituitary hormones and show plasticity of expression. Histochemistry 93: 183, 1990.
12. Vrontakis M.E., Sano T., Kovaks K., Friesen H.G. Presence of galanin-like immunoreactivity in nontumorous corticotrophs and corticotroph adenomas of the human pituitary. J. Clin Endocrinol. Metab. 70: 747, 1990.
13. O'Halloran D.J., Jones P.M., Steel J.H., Gon G., Giaid A., Ghatei A., Polak J.M., Bloom S.R. Effect of endocrine manipulation on anterior pituitary galanin in the rat. Endocrinology 127: 467, 1990.
14. Murakami Y., Ohshima K., Mochizuki T., Yanaihara N. Effects of human galanin on growth hormone prolactin and antidiuretic hormone secretion in normal men. J. Clin. Endocrinol. Metab. 77: 1436, 1993.
15. Ghigo E., Maccario M., Arvat E., Valetta MR., Valente F., Nicolosi M., Mazza E., Martina V., Cocchi D., Camanni F. Interactions of galanin and arginine on growth hormone, prolactin and insulin secretion in man. Metabolism 41: 85, 1992.
16. Davis T.M., Burrin J.M., Bloom S.R. Growth hormone (GH) release in response to GH-releasing hormone in man is 3-fold enhanced by galanin. J. Clin. Endocrinol. Metab. 65: 1248, 1987.
17. Koshiyama H., Kato Y., Inoue T., Murakami Y., Ishikawa Y., Yanaihara N., Imura H. Central galanin stimulates pituitary prolactin secretion in rats: possible involvement of the hypothalamic vasoactive intestinal polypeptide. Neurosci Lett. 75: 49, 1987.
18. Arvat E., Gianotti L., Ramunni J., Grottoli S., Brossa P.C., Bertagna A., Camanni F., Ghigo E. Effect of galanin on basal and stimulated secretion of prolactin,gonadotropins, thyrotropin, adrenocorticotropin and cortisol in humans. Eur. J. Endocrinol 133: 300, 1995.
19. Maiter D.M., Hooi S.C., Koenig J.I., Martin J. Galanin is a physiological regulator of spontaneous pulsatile secretion of growth hormone in the male rat. Endocrinology 126: 1216, 1990.
20. Invitti C., Pecori Giraldi F., Tagliaferri A., Scacchi M., Dubini A., Cavagnini F. Enhanced prolactin responsiveness to galanin in patients with Cushing's disease. Clin. Endocrinol. (Oxf.) 39: 213, 1993.
21. Giustina A., Girelli A., Licini M., Schettini M., Negro-Vilar A. Thyrotropin and prolactin secretion are not affected by porcine and rat galanin in normal subjects. Horm. Metab. Res. 24: 351, 1992.
22. Hinkle PM., Tashjian AH. Receptors for TRH in prolactin producing rat pituitary cells in culture. J. Biol. Chem. 248: 6180, 1973
23. Alba-Roth J., Müller A.O., Schopohl J., von Werder K. Arginine stimulates growth hormone secretion by suppressing endogenous somatostatin secretion. J. Clin. Endocrin. Metab. 57: 781, 1988.
24. Muller E.E., Nisticò G. Brain messangers and the pituitary. Academic Press, San Diego, 1989.
25. Moncada S., Radonski MW., Palmer RN. Endothelium-derived relaxing factor. Identification as nitric oxide and role in the control of the vascular tone and platelet function. Biochem. Pharmacol. 37: 2495, 1988
26. Nordstrom O., Melander T., Hokfelt T., Bartfai T., Goldstein M. Evidence for an inhibitory effect of the peptide galanin on dopamine release from rat median eminence. Neurosci. Lett. 73: 21, 1987.
27. Giustina A., Bussi AR., Doga M., Licini M., Schettino M., Wehremberg WB. Effects of metoclopramide on the growth hormone response to galanin in normal man. Horm. Metab. Res. 25: 489, 1993.
28. Ghigo E., Goffi S., Molinatti GM., Camanni F., Massara F. Prolactin and TSH response to both domperidone and TRH in normal and hyperprolactinemic women after dopamine synthesis blockade. Clin. Endocrinol. (Oxf.) 23: 155, 1985.
29. Martinez de la Escalera G., Weiner R.I. Mechanisms by which the transient removal of dopamine regulation potentiates the prolactin releasing action of TRH. Neuroendocrinology 47: 186, 1988.
30. Inoue T., Kato Y., Koshiyama H., Yanaihara N., Imura H. Galanin stimulates the release of vasoactive intestinal polypeptide from perfused hypothalamic fragments in vitro and from periventricular structures into the cerebrospinal fluid in vivo in the rat. Neurosci. Lett. 85: 95, 1988.
31. Martinez De la Escalera G., Weiner R.I. Dissociation of dopamine from its receptors as a signal in the pleiotropic hypothalamic regulation of prolactin secretion. Endocr. Rev. 13: 241, 1992.
32. Kato Y., Iwasaki Y., Iwasaki J., Abe H., Yanaihara N., Imura H. Prolactin release by vasoactive intestinal polypeptide in rats. Endocrinology 103: 554, 1978.
33. Wynick D., Hammond P.J., Akinsanya K.O., Bloom S.R. Galanin regulates basal and oestrogen-stimulated lactotroph function. Nature 364: 529, 1993.
34. Giustina A., Licini M., Bussi AR., Girelli A., Pizzocolo G., Schettino M., Negro-Vilar A. Effects of sex and age on the growth hormone response to galanin in healthy human subjects. J. Clin. Endocrinol. Metab. 76: 1369, 1993
35. Giustina A., Licini M., Schettino M., Doga M., Pizzocolo G., Negro-Vilar A. Physiological role of galanin in the regulation of anterior pituitary function in humans Am. J. Physiol. 266: 57, 1994.