Pituitary adenylate cyclase-activating peptide in sensory and autonomic ganglia: Localization and regulation

Annals of the New York Academy of Sciences

Volumn 805, Issue , 1996, Pages 410-426

  Sundler, F ^a,d   Ekblad, E ^a   Hannibal, J ^c   Moller, K ^a   Zhang, Y Z ^a   Mulder, H ^a   Elsas T ^a   Grunditz, T ^b   Danielsen, N ^a   Fahrenkrug, J ^c   Uddman, R ^b  

^a LUND UNIVERSITY   (Sweden)

^b Mental Health Services CPH   (Denmark)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d Department of Physiology   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE 27;

ANTINOCICEPTION; AUTONOMIC GANGLION; CONFERENCE PAPER; GENE INDUCTION; HORMONE DETERMINATION; IMMUNOCYTOCHEMISTRY; INTESTINE INNERVATION; NERVE FIBER TRANSECTION; NONHUMAN; PARASYMPATHETIC NERVE; PROTEIN INDUCTION; PROTEIN LOCALIZATION; RAT; SENSORY GANGLION; SYMPATHETIC GANGLION; TISSUE DISTRIBUTION;

EID: 0030481440     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1996.tb17501.x     Document Type: Conference Paper

References (76)

1. MIYATA, A., A. ARIMURA, R. R. DAHL, N. MINAMINO, A. UEHARA, L. JIANG, M. D. CULLER & D. H. COY. 1989. Isolation of a novel 38 residue-hypothalamic polypeptide which stimulates adenylate cyclase in pituitary cells. Biochem. Biophys. Res. Commun. 164: 567-574.
2. ARIMURA, A. 1992. Pituitary adenylate cyclase activating polypeptide (PACAP): Discovery and current status of research. Regul. Pept. 37: 287-303.
3. CARDELL, L. O., R. UDDMAN, A. Lurs & F. SUNDLER. 1991. Pituitary adenylate cyclase activating peptide (PACAP) in guinea-pig lung: Distribution and dilatory effects. Regul. Pept. 36: 379-390.
4. UDDMAN, R., A. Lurs, A. ARIMURA & F. SUNDLER. 1991. Pituitary adenylate cyclase-activating peptide (PACAP), a new vasoactive intestinal peptide (VIP)-like peptide in the respiratory tract. Cell Tissue Res. 265: 197-201.
5. SUNDLER, F., E. EKBLAD, A. ABSOOD, R. HÅKANSON, K. KÖVES & A. ARIMURA. 1992. Pituitary adenylate cyclase activating peptide: A novel vasoactive intestinal peptide-like neuropeptide in the gut. Neuroscience 46: 439-454.
6. SHEN, Z., L. T. LARSSON, G. MALMFORS, A. ABSOOD, R. HÅKANSON & F. SUNDLER. 1992. A novel neuropeptide, pituitary adenylate cyclase-activating polypeptide (PACAP), in human intestine: Evidence for reduced content in Hirschsprung's disease. Cell Tissue Res. 269: 369-374.
7. KÖVES, K., A. ARIMURA, S. VIGH, A. SOMOGYVÁRI-VIGH & J. MILLER. 1993. Immunohistochemical localization of PACAP in the ovine digestive system. Peptides 14: 449-455.
8. FRIDOLF, T., F. SUNDLER & B. AHRÉN. 1992. Pituitary adenylate cyclase-activating polypeptide (PACAP): Occurrence in rodent pancreas and effects on insulin and glucagon secretion in the mouse. Cell Tissue Res. 269: 275-279.
9. RAVN STEENSTRUP, B., P. ALM, J. HANNIBAL, J. C. JÖRGENSEN, C. FALLE, J. JUNGE, H. B. CHRISTENSEN, B. OiTESEN & J. PAHRENKRUG. 1995. Pituitary adenylate cyclase-activating polypeptide: Occurrence and relaxant effect in female genital tract. Am. J. Physiol. 269: E108-E117.
10. TOBIN, G., A. ASZTÉLY, A. V. EDWARDS, J. EKSTRÖM, R. HÅKANSON & F. SUNDLER. 1995. Presence and effects of pituitary adenylate cyclase activating peptide in the submandibular gland of the ferret. Neuroscience 66: 227-235.
11. WANG, Z.-Y., P. ALM & R. HÅKANSON. 1995. Distribution and effects of pituitary adenylate cyclase-activating peptide in the rabbit eye. Neuroscience 69: 297-308.
12. ARIMURA, A., A. SOMOGYVÁRI-VIGH, A. MIYATA, K. MIZUNO, D. H. COY & C. KITADA. 1991. Tissue distribution of PACAP as determined by RIA: Highly abundant in the rat brain and testes. Endocrinology 129: 2787-2789.
13. GHATEI, M. A., K. TAKAHASHI, Y. SUZUKI, J. GARDINER, P. M. JONES & S. R. BLOOM. 1993. Distribution, molecular characterization of pituitary adenylate cyclase-activating polypeptide and its precursor encoding messenger RNA in human and rat tissues. J. Endocrinol. 136: 159-166.
14. HARMAR, T. & E. LUTZ. 1994. Multiple receptors for PACAP and VIP. Trends Pharmacol. Sci. 15: 97-99.
15. RAWLINGS, S. R. 1994. PACAP, PACAP receptors, and intracellular signalling. Mol. Cell. Endocrinol. 101: C5-C9.
16. USDIN, T. B., T. I. BONNER & E. MEZEY. 1994. Two receptors for vasoactive intestinal polypeptide with similar specificity and complementary distributions. Endocrinology 135: 2662-2678.
17. SPENGLER, D., C. WAEBER, C. PANTALONI, F. HOLSBOER, J. BOCKAERT, P. H. SEEBURG & L. JOURNOT. 1993. Differential signal transduction by five splice variants of the PACAP-receptor. Nature 365: 170-175.
18. JOURNOT, L., C. WAEBER, C. PANTALONI, F. HOLSBOER, P. H. SEEBURG, J. BOCKAERT & D. SPENGLER. 1994. Differential signal transduction by six splice variants of the pituitary adenylate cyclase-activating peptide (PACAP) receptor. Biochem. Soc. Trans. 23: 133-137.
19. JU, G., T. HÖKFELT, E. BRODIN, J. FAHRENKRUG, J. A. FISCHER, P. FREY, R. P. ELDE & J. C. BROWN. 1987. Primary sensory neurons of the rat showing calcitonin gene-related peptide (CGRP) immunoreactivity and their relation to substance P-, somatostatin-, galanin-, vasoactive intestinal polypeptide- and cholecystokinin-immunoreactive ganglion cells. Cell Tissue Res. 247: 417-431.
20. MERIGHI, A., S. KAR, S. J. GIBSON, S. GHIDELLA, A. GOBETTO, S. PEIRONE & J. M. POLAK. 1990. The immunocytochemical distribution of seven peptides in the spinal cord and dorsal root ganglia of horse and pig. Anat. Embryol. 181: 271-280.
21. NOGUCHI, K., M. DE LEON, R. L. NAHIN, E. SENBA & M. A. RUDA. 1993. Quantification of axotomy-induced alteration of neuropeptide mRNAs in dorsal root ganglion neurons with special reference to neuropeptide Y mRNA and the effects of neonatal capsaicin treatment. J. Neurosci. Res. 35: 54-66.
22. HÖKFELT, T., X. ZHANG & Z. WIESENFELD-HALLIN. 1994. Messenger plasticity in primary sensory neurons following axotomy and its functional implications. Trends Neurosci. 17: 22-29.
23. VILLAR, M. J., R. CORTES, E. THEODORSSON, Z. WIESENFELD-HALLIN, M. SCHALLING, J. FAHRENKRUG, P. C. EMSON & T. HÖKFELT. 1989. Neuropeptide expression in rat dorsal root ganglion cells and spinal cord after peripheral nerve injury with special reference to galanin. Neuroscience 33: 587-604.
24. WAKISAKA, S., K. C. KAJANDER & G. J. BENNETT. 1991. Increased neuropeptide Y (NPY)-like immunoreactivity in rat sensory neurons following peripheral axotomy. Neurosci. Lett. 124: 200-203.
25. WIESENFELD-HALLIN, Z., T. BARTFAI, & T. HÖKFELT. 1992. Galanin in sensory neurons in the spinal cord. Front. Neuroendocrinol. 13: 319-343.
26. MOLLER, K., Y.-Z. ZHANG, R. HÅKANSON, A. LUTS, B. SJÖLUND, R. UDDMAN & F. SUNDLER. 1993. Pituitary adenylate cyclase activating peptide is a sensory neuropeptide: Immunocytochemical and immunochemical evidence. Neuroscience 57: 725-732.
27. LEGRADI, G., T. J. GÖRCS & A. ARIMURA. 1994. PACAP-like immunoreactivity and binding sites in putative nociceptive pathways of the spinal cord and brainstem. In Vasoactive Intestinal Peptide, Pituitary Adenylate Cyclase Activating Polypeptide and Related Regulatory Peptides, from Molecular Biology to Clinical Applications. G. Rosselin, Ed.: 283-292. World Scientific, Singapore.
28. ZHANG, Y.-Z., B. SJÖLUND, K. MOLLER, R. HÅKANSON & F. SUNDLER. 1993. Pituitary adenylate cyclase activating peptide produces a marked and long-lasting depression of a c-fibre-evoked flexion reflex. Neuroscience 57: 733-737.
29. YAMAMOTO, T. & I. TATSUNO. 1995. Antinociceptive effect of intrathecally administered pituitary adenylate cyclase activating polypeptide (PACAP) on the rat formalin test. Neurosci. Lett. 184: 32-35.
30. WARREN, J. B., S. W. LARKIN, M. COUGHLAN, R. KAJEKAR & T. J. WILLIAMS. 1992. Pituitary adenylate cyclase activating polypeptide is a potent vasodilator and oedema potentiator in rabbit skin in vivo. Br. J. Pharmacol. 106: 331-334.
31. MULDER, H., R. UDDMAN, K. MOLLER, Y.-Z. ZHANG, E. EKBLAD, J. ALUMETS & F. SUNDLER. 1994. Pituitary adenylate cyclase activating polypeptide expression in sensory neurons. Neuroscience 63: 307-312.
32. HANNIBAL, J., J. D. MIKKELSEN, H. CLAUSEN, J. J. HOLST, B. S. WULFF & J. FAHRENKRUG. 1995. Gene expression of pituitary adenylate cyclase activating polypeptide (PACAP) in the rat hypothalamus. Regul. Pept. 55: 133-148.
33. ZHANG, Y.-Z., J. HANNIBAL, Q. ZHAO, K. MOLLER, N. DANIELSEN, J. FAHRENKRUG & F. SUNDLER. 1996. Pituitary adenylate cyclase activating peptide (PACAP) expression in the rat dorsal root ganglia: Upregulation after peripheral nerve injury. Neuroscience 74: 1099-1110.
34. ZHANG, Q., T.-J. SHI, R.-R. JI, Y.-Z. ZHANG, F. SUNDLER, J. HANNIBAL, J. FAHRENKRUG & T. HÖKFELT. 1995. Expression of pituitary adenylate cyclase-activating polypeptide in dorsal root ganglia following axotomy: Time course and coexistence. Brain Res. 705: 149-158.
35. OHKUBO, S., C. KIMURA, K. OGI, K. OKAZAKI, M. HOSOYA, H. ONDA, A. MIYATA, A. ARIMURA & M. FUJINO. 1992. Primary structure and characterization of the precursor to human pituitary adenylate cyclase activating polypeptide. DNA Cell Biol. 11: 21-30.
36. HURLEY, J. D., J. V. GARDINER, P. M. JONES & S. R. BLOOM. 1995. Cloning and molecular characterization of complementary deoxyribonucleic acid corresponding to a novel form of pituitary adenylate cyclase-activating polypeptide messenger ribonucleic acid in the rat testis. Endocrinology 136: 550-557.
37. KLEIN, C. M., R. E. COGGESHALL, S. M. CARLTON, K. N. WESTLUND & L. S. SORKLN. 1990. Changes in calcitonin gene-related peptide immunoreactivity in the rat dorsal horn following electrical stimulation of the sciatic nerve. Neurosci. Lett. 115: 149-154.
38. HÖKFELT, T., Z. WIESENFELD-HALLIN, M. VILLAR & T. MELANDER. 1987. Increase of galanin-like immunoreactivity in rat dorsal root ganglion cells after peripheral axotomy. Neurosci. Lett. 83: 217-220.
39. KASHIBA, H., E. SENBA, Y. UEDA & M. TAHYAMA. 1994. Co-localized but target-unrelated expression of vasoactive intestinal polypeptide and galanin in rat dorsal root ganglion neurons after peripheral nerve crush injury. Brain Res. 582: 47-57.
40. DEUTSCH, P. J. & Y. SUN. 1992. The 38-amino acid form of pituitary adenylate cyclase-activating polypeptide stimulates dual signaling cascades in PC12 cells and promotes neurite outgrowth. J. Biol. Chem. 267: 5108-5113.
41. HERNANDEZ, A., B. KIMBALL, G. ROMANCHUK & M. W. MULHOLLAND. 1995. Pituitary adenylate cyclase-activating peptide stimulates neurite growth in PC12 cells. Peptides 16: 927-932.
42. ARLMURA, A., A. SOMOGYAVARI-VIGH, C. WEILL, R. C. FIORE, I. TATSUNO, V. BAY & D. E. BRENNEMAN. 1994. PACAP functions as a neurotrophic factor. Ann. N.Y. Acad Sci. 739: 228-243.
43. BRENNEMAN, D. E. & L. E. EIDEN. 1986. Vasoactive intestinal peptide and electrical activity influence neuronal survival. Proc. Natl. Acad. Sci. USA 83: 1159-1162.
44. COLBERT, R. A., D. BALBI, A. JOHNSON, J. A. BAILEY & J. M. ALLEN. 1994. Vasoactive intestinal peptide stimulates neuropeptide Y gene expression and causes neurite extension in PC 12 cells through independent mechanisms. J. Neurosci. 14: 7141-7147.
45. HOSHINO, M., M. LI, L. Q. ZHENG, M. SUZUKI, T. MOCHIZUKI & N. YANAIHARA. 1993. Pituitary adenylate cyclase activating peptide and vasoactive intestinal polypeptide: Differentiation effects on human neuroblastoma NB-OK-1 cells. Neurosci. Lett. 159: 35-38.
46. FRÖDIN, M., J. HANNIBAL, B. S. WULFF, S. GAMMELTOFT & J. FAHRENKRUG. 1995. Neuronal localization of pituitary adenylate cyclase-activating polypeptide 38 in the adrenal medulla and growth inhibitory effect on chromaffin cells. Neuroscience 65: 599-608.
47. SCHOMERUS, E., A. POCH, R. BUNTING, W. T. MASON & C. A. MCARDLE. 1994. Effects of pituitary adenylate cyclase-activating polypeptide in the pituitary: Activation of two signal transduction pathways in the gonadotrope-derived αT3-1 cell line. Endocrinology 134: 315-323.
48. RENE, F., F. BARTHEL, J. M. FELIX, J. L. ROBERTS, A. C. GORE & J. P. LOEFFLER. 1994. Pituitary adenylate cyclase activating peptide (PACAP) stimulates cAMP-dependent transcription and promotes survival of cerebellar granule neurons "in vivo." Soc. Neurosci. Abstr. 20: 1352.
49. MOLLER, K. & F. SUNDLER. 1996. Expression of pituitary adenylate cyclase activating peptide (PACAP) and PACAP type I receptors in the rat adrenal medulla. Regul. Pept. 63: 129-139.
50. ZIGMOND, R. E., H. HYATT-SACHS, C. BALDWIN, X. M. QU, Y. SUN, T. W. MCKEON, R. C. SCHREIBER & U. VAIDYANATHAN. 1992. Phenotypic plasticity in adult sympathetic neurons: Changes in neuropeptide expression in organ culture. Proc. Natl. Acad. Sci. USA 89: 1507-1511.
51. USHIDA, D., S. SHIODA, A. TAKAKI & A. ARIMURA. 1994. Cytoprotective action of pituitary adenylate cyclase activating polypeptide (PACAP) in ischemia-induced neuronal cell death in rat hippocampus. Soc. Neurosci. Abstr. 20: 442.
52. LUNDBERG, J. M., C.-R. MARTLING & T. HÖKFELT. 1988. Airways, oral cavity and salivary glands: Classical transmitters and peptides in sensory and autonomic motor neurons. In Handbook of Chemical Neuroanatomy. Vol. 6, The Peripheral Nervous System. A. Björklund, T. Hökfelt & C. Owman, Eds.: 391-444. Elsevier. Amsterdam, the Netherlands.
53. SUNDLER, F., G. BÖTTCHER, E. EKBLAD & R. HÅKANSON. 1993. PP, PYY, and NPY. Occurrence and distribution in the periphery. In The Biology of Neuropeptide Y and Related Peptides. W. F. Colmers & C. Wahlestedt, Eds.: 157-195. Humana Press Inc. Totowa, NJ.
54. KUMMER, W. 1987. Galanin- and neuropeptide Y- like immunoreactivities coexist in paravertebral sympathetic neurones of the cat. Neurosci. Lett. 78: 127-131.
55. AUREN, B., G. BÖTTCHER, S. KOWALYK, B. E. DUNNING, F. SUNDLER & G. J. TABORSKY JR. 1990. Galanin is co-localized with noradrenaline and neuropeptide Y in dog pancreas in celiac ganglion. Cell Tissue Res. 261: 49-58.
56. SCHREIBER, R. C., H. HYATT-SACHS, T. A. BENNETT & R. E. ZIGMOND. 1994. Galanin expression increases in adult rat sympathetic neurons after axotomy. Neuroscience 60: 17-27.
57. SASEK, C. A. & R. E. ZIGMOND. 1989. Localization of vasoactive intestinal peptide- and peptide histidine isoleucine amide-like immunoreactivities in the rat superior cervical ganglion and its nerve trunks. J. Comp. Neurol. 280: 522-532.
58. ANDERSON, C. R., S. L. EDWARDS, J. B. FURNESS, D. S. BREDT & S. H. SNYDER. 1993. The distribution of nitric oxide synthase-containing autonomie preganglionic terminals in the rat. Brain Res. 614: 78-85.
59. FURNESS, J. B. & C. R. ANDERSON. 1993. Origins of nerve terminals containing nitric oxide synthase in the guinea-pig coeliac ganglion. J. Auton. Nerv. Syst. 46: 47-54.
60. OKAMURA, H., K. UMEHARA, N. TADAKI, Y. HISA, H. ESUMI & Y. IBATA. 1995. Sympathetic preganglionic neurons contain nitric oxide synthase and project to the superior cervical ganglion: Combined application of retrograde neuronal tracer and NADPH-diaphorase histochemistry. Brain Res. Bull. 36: 491-494.
61. HYATT-SACHS, H., R. C. SCHREIBER, T. A. BENNETT & R. E. ZIGMOND. 1993. Phenotypic plasticity in adult sympathetic ganglia in vivo: Effects of deafferentation and axotomy on the expression of vasoactive intestinal peptide. J. Neurosci. 13: 1642-1653.
62. RAO, M. S., Y. SUN, U. VAIDYANATHAN, S. C. LANDIS & R. E. ZIOMOND. 1992. Regulation of substance P is similar to that of vasoactive intestinal peptide after axotomy or explantation of the rat superior cervical ganglion. J. Neurobiol. 24: 571-580.
63. KRUKOFF, T. L. 1987. Coexistence of neuropeptides in sympathetic preganglionic neurons of the cat. Peptides 8: 109-112.
64. DAGERLIND, A., X. ZHANG, S. BRIMUOIN, B. LINDH & T. HÖKFELT. 1994. Effects of preganglionic sympathectomy on peptides in the rat superior cervical ganglion. Neuroreport 5: 909-912.
65. PEUNOVA, N. & G. ENIKOLOPOV. 1995. Nitric oxide triggers a switch to growth arrest during differentiation of neuronal cells. Nature 375: 68-73.
66. SHADIACK, A. M., S. A. VACCARIELLO & R. E. ZIGMOND. 1995. Galanin expression in sympathetic ganglia after partial axotomy is highly localized to those neurons that are axotomized. Neuroscience 65: 1119-1127.
67. DICICCO-BLOOM, E. 1996. Region-specific regulation of neurogenesis by VIP and PACAP: Direct and indirect modes of action. Ann. N.Y. Acad Sci. This volume.
68. MAY, V. & K. M. BRAAS. 1995. Pituitary adenylate cyclase-activating polypeptide (PACAP) regulation of sympathetic neuron neuropeptide Y and catecholamine expression. J. Neurochem. 65: 978-987.
69. 2+. Jpn. J. Pharmacol. 66: 323-330.
70. RIUS, R. A., A. GUIDOTTI & E. COSTA. 1994. Pituitary adenylate cyclase activating polypeptide (PACAP) potently enhances tyrosine hydroxylase (TH) expression in adrenal chromaffm cells. Life Sci. 54: 1735-1743.
71. WATANABE, T., Y. MASUO, H. MATSUMOTO, N. SUZUKI, T. OHTAKI, Y. MASUDA, C. KITADA, M. TSUDA & M. FUJKO. 1992. Pituitary adenylate cyclase activating polypeptide provokes cultured rat chromaffin cells to secrete adrenaline. Biochem. Biophys. Res. Commun. 182: 403-411.
72. 2+-dependent stimulatiory effect of pituitary adenylate cyclase-activating polypeptide on catecholamine secretion from cultured porcine adrenal medullary chromaffm cells. Endocrinology 132: 1757-1765.
73. PINCUS, D. W., E. DiCicco-BLOOM & I. B. BLACK. 1994. Trophic mechanisms regulate mitotic neuronal precursors: Role of vasoactive intestinal peptide (VIP). Brain Res. 663: 51-60.
74. MULDER, H., R. UDDMAN, K. MOLLER, T. ELSÅS, E. EKBLAD, J. ALUMETS & F. SUNDLER. 1995. Pituitary adenylate cyclase activating polypeptide is expressed in autonomic neurons. Regul. Pept. 59: 121-128.
75. PORTBURY, A. L., K. MCCONALOGUE, J. B. FURNESS & H. M. YOUNG. 1995. Distribution of pituitary adenylyl cyclase activating peptide (PACAP) immunoreactivity in neurons of the guinea-pig digestive tract and their projections in the ileum and colon. Cell Tissue Res. 279: 385-392.
76. EKBLAD, E., H. MULDER & F. SUNDLER. 1996. Vasoactive intestinal peptide expression in enteric neurons is upregulated by both colchicine and axotomy. Regul. Pept. 63: 113-121.