Association between flow cytometric S-phase fraction and apoptotic rate in breast cancer

Communications in Clinical Cytometry

Volumn 26, Issue 4, 1996, Pages 281-285

  Samoszuk, Michael K ^a   Sallash, Gretchen ^a   Chen, Kevin ^a   Carlton, Esther ^a   Oldaker, Teri ^a  

^a QUEST DIAGNOSTICS NICHOLS INSTITUTE   (United States)

Author keywords

apoptosis; flow cytometry; S phase fraction; TUNEL

Indexed keywords

APOPTOSIS; ARTICLE; BREAST CANCER; CELL CYCLE S PHASE; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; PRIORITY JOURNAL;

APOPTOSIS; BREAST NEOPLASMS; DNA, NEOPLASM; FEMALE; FLOW CYTOMETRY; HUMANS; S PHASE;

EID: 0030480991     PISSN: 01964763     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0320(19961215)26:4<281::AID-CYTO7>3.0.CO;2-F     Document Type: Article

References (21)

1. Allan DJ, Howell A, Roberts SA, Williams GT, Watson RJ, Coyde JD, Clarke RB, Laidlaw IJ, Potten CS:Reduction in apoptosis relative to mitosis in histologically normal epithelium accompanies fibrocystic change and carcinoma of the premenopausal human breast. J Pathol 163:337-342, 1991.
2. Ansari B, Coates PJ, Greenstein BD, Hall PA:In situ end labeling detects DNA strand breaks in apoptosis and other physiological and pathological states. J Pathol 170:1-8, 1993.
3. Baretton GB, Diebold J, Christoforis G, et al.:Apoptosis and immunohistochemical bcl-2 expression in colorectal adenomas and carcinomas. Cancer 77:255-264, 1996.
4. Brown RW, Allred DC, Clark GM, Osborne CK, Hilsenbeck SG:Prognostic value of Ki-67 compared to S-phase fraction in axillary node-negative breast cancer. Clin Cancer Res 2:585-592, 1996.
5. Castle PV, Heidelberger KP, Bromberg J, Ou X, Dole M, Nunez G:Expression of apoptosis-suppressing protein bcl-2, in neuroblastoma is associated with unfavorable histology and N-myc amplification. Am J Pathol 163:337-342, 1993.
6. Czader M, Mazur J, Pettersson M, et al.:Prognostic significance of proliferative and apoptotic fractions in low grade follicle center cell-derived non-Hodgkin's lymphomas. Cancer 77:1180-1188, 1996
7. de Moor BM, Clark GM, Osborne CK, Allred DC:Apoptosis in node-negative breast cancer. Proceedings of the 18th Annual San Antonio Breast Cancer Symposium, 58A, 1995.
8. Evan GI, Littlewood TD:The role of c-myc in cell growth. Curr Opin Genet Dev 3:44-49, 1993.
9. Gavrieli Y, Sherman Y, Ben-Sasson SA:Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 119:493-501, 1992.
10. Hedley DW, Clark GM, Conelisse CJ, Killander D, Kute T, Merkel D:Consensus review of the clinical utility of DNA cytometry in carcinoma of the breast. Cytometry 14:482-485, 1993.
11. Hedley DW, Frielander MI, Taylor IW, Ruggs CA, Musgrove EA:Methods of analysis of cellular DNA content of paraffin-embedded pathological material using flow cytometry. J Histochem Cytochem 31:1333-1335, 1983.
12. Hockenberry DM:The bcl-2 oncogene and apoptosis. Semin Immunol 4:413-420, 1992.
13. Huovinen R, Warn A, Collan Y:Mitotic activity, apoptosis, and TRPM-2 mRNA expression in DMBA-induced rat mammary carcinoma treated with anti-estrogen toremifence. Int J Cancer 55:685-691, 1993.
14. Kerr JFR, Winterford CM, Harmon BV:Apoptosis:Its significance in cancer and cancer therapy. Cancer 73:2013-2026, 1994.
15. Koskinen PJ, Alitalo K:Role of myc amplification and overexpression in cell growth, differentiation, and death. Semin Cancer Biol 4:3-12, 1993.
16. Lipponen P, Aaltomaa S:Apoptosis in bladder cancer as related to standard prognostic factors and prognosis. J Pathol 173:333-339, 1994.
17. Lipponen P, Aaltomaa S, Kosma VM, Syrjanen K:Apoptosis in breast cancer as related to histopathological characteristics and prognosis. Eur J Can 30A:2068-2073, 1994.
18. Meyer JS, Lee JY:Relationships of S-phase fraction of breast carcinoma in relapse to duration of remission, estrogen receptor content, therapeutic responsiveness, and duration of survival. Cancer Res 40:1890-1896, 1980
19. Shankey TV, Rabinovitch PS, Bagwell B, Bauer KD, Duque RE, Hedley DW, Mayhall BH, Wheeless L:Guidelines for the implementation of clinical DNA cytometry. Cytometry 14:472-477, 1993.
20. Thompson CB:Apoptosis in the pathogenesis and treatment of disease. Science 266:1821-1828, 1995.
21. Wyllie AH:Apoptosis and the regulation of cell numbers in normal and neoplastic tissues:an overview. Cancer Metast Rev 11:95-103, 1992.