Long-term effects of chronic ethanol on muscarinic receptor binding in rat brain

Alcoholism: Clinical and Experimental Research

Volumn 20, Issue 9, 1996, Pages 1613-1617

  Rothberg, Brad S ^a   Hunter, Bruce E ^a,b   Walker, Don W ^a,b   Anderson, Jonathon F ^a   Anderson, Kevin J ^a,c  

^a UNIVERSITY OF FLORIDA   (United States)

^b Veteran's Health Administration   (United States)

^c UNIVERSITY OF FLORIDA HEALTH   (United States)

Author keywords

Autoradiography; Carbachol; Chronic Ethanol; Hippocampus

Indexed keywords

ALCOHOL; CARBACHOL; CHOLINERGIC RECEPTOR STIMULATING AGENT; MUSCARINIC RECEPTOR; MUSCARINIC RECEPTOR BLOCKING AGENT; QUINUCLIDINYL BENZILATE; TRITIUM;

ALCOHOLISM; AMNESIA; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CHOLINERGIC SYSTEM; CONTROLLED STUDY; HIPPOCAMPUS; MALE; MEMORY; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BINDING;

ANIMALS; AUTORADIOGRAPHY; BRAIN; CARBACHOL; CEREBRAL CORTEX; ETHANOL; HIPPOCAMPUS; MALE; QUINUCLIDINYL BENZILATE; RATS; RECEPTORS, MUSCARINIC; THALAMUS;

ANIMALIA; TRITIUM;

EID: 0030480584     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.1996.tb01706.x     Document Type: Article

References (23)

1. Butters N: Alcoholic Korsakoffs syndrome: Some unresolved issues concerning etiology, neuropathology and cognitive deficits. J Clin Exp Neuropsychol 7:181-210, 1985
2. Victor M, Adams RD, Collins GH: The Wernicke-Korsakoff Syndrome. P. A. Davis, Philadelphia, 1971, 206 pp
3. Fehr KA, Kalant H, LeBlanc AE: Residual learning deficit after heavy exposure to cannabis or alcohol in rats. Science 192:1248-1251, 1976
4. Hodges H, Allen Y, Sinden J, Mitchell SN, Arendt T, Lantos PL, Gray JA: The effects of cholinergic drugs and cholinergic-rich foetal neural transplants on alcohol-induced deficits in radial maze performance in rats. Behav Brain Res 43:7-28, 1991
5. Walker DW, Freund G: Impairment of timing behavior following prolonged alcohol consumption in rats. Science 182:597-599, 1973
6. Walker DW, Barnes DE, Zornetzer SF, Hunter BE, Kubanis P: Neuronal loss in hippocampus induced by prolonged ethanol consumption in rats. Science 209:711-713, 1980
7. Walker DW, King MA, Hunter BE: Alterations in the structure of the hippocampus after long-term ethanol consumption, in Hunt WA, Nixon SJ (eds): Alcohol-Induced Brain Damage, NIAAA Research Monograph 22. Washington, D.C., U.S. Government Printing Office, 1993, pp 231-247
8. Lovinger DM, White G, Weight FF: NMDA receptor-mediated synaptic excitation selectively inhibited by ethanol in hippocampal slice from adult rat. J Neurosci 10:1372-1379, 1990
9. Tremwell MF, Hunter BE: Effects of chronic ethanol ingestion on long-term potentitation remain even after a prolonged recovery from ethanol exposure. Synapse 17:141-148, 1994
10. Bartus RT, Dean RL III, Beer B, Lippa AS: The cholinergic hypothesis of geriatric memory dysfunction. Science 217:408-417, 1982
11. Arendt T, Allen Y, Marchbanks RM, Schugens MM, Sinden J, Lantos PL, Gray JA: Cholinergic system and memory in the rat: Effects of chronic ethanol, embryonic basal forebrain transplants and excitotoxic lesions of the cholinergic basal forebrain projection system. Neuroscience 33:435-462, 1989
12. Rothberg BS, Hunter BE: Chronic ethanol treatment differentially affects muscarinic receptor responses in rat hippocampus. Neurosci Lett 132:243-246, 1991
13. Rothberg BS, Hunter BE: Cholinergic and serotonergic sensitivity in hippocampal slices following chronic ethanol exposure. Soc Neurosci Abstr 19:609, 1993
14. Rothberg BS, Yasuda RP, Satkus SA, Wolfe BB, Hunter BE: Effects of chronic ethanol on cholinergic actions in rat hippocampus: Electrophysiological studies and quantification of m1-m5 muscarinic receptor subtypes. Brain Res 631:227-234, 1993
15. Rogers CJ, Hunter BE: Chronic ethanol treatment reduces inhibition in CA1 of the rat hippocampus. Brain Res Bull 28:587-592, 1992
16. Cortes R, Palacios JM: Muscarinic cholinergic receptor subtypes in the rat brain. I. Quantitative autoradiographic studies. Brain Res 362:227-238, 1986
17. Bauer A, Schulz J-B, Zilles K: Muscarinic desensitization after septal lesions in rat hippocampus: Evidence for the involvement of G-proteins. Neuroscience 47:95-103, 1992
18. Potter LT, Ferrendelli CA: Affinities of different cholinergic agonists for the high and low affinity states of hippocampal M1 muscarine receptors. J Pharmacol Exp Ther 248:974-978, 1989
19. Shanley BC, Wilce PA: Receptor changes associated with ethanol-induced brain damage, in Hunt WA, Nixon SJ (eds): Alcohol-Induced Brain Damage, NIAAA Research Monograph 22. Washington, D.C., U.S. Government Printing Office, 1993, pp 299-324
20. Muller P, Britton RS, Seeman P: The effects of long-term ethanol on brain receptors for dopamine, acetylcholine, serotonin and noradrenaline. Eur J Pharmacol 65:31-37, 1980
21. Pietrzak ER, Wilce PA, Shanley BC: The effect of chronic ethanol consumption on muscarinic receptors in rat brain. Neurochem Int 12:447-452, 1988
22. Pietrzak ER, Wilce PA, Shanley BC: Interaction of chronic ethanol consumption and aging on muscarinic receptors in rat brain. J Pharmacol Exp Ther 252:869-874, 1989
23. Madison DV, Lancaster B, Nicoll RA: Voltage clamp analysis of cholinergic action in the hippocampus. J Neurosci 7:733-741, 1987