The correlation of Ki-67 staining indices with tumour doubling times in regrowing non-functioning pituitary adenomas

Acta Neurochirurgica

Volumn 138, Issue 12, 1996, Pages 1449-1455

  Ekramullah, S M ^a   Saitoh, Y ^a   Arita, N ^a   Ohnishi, T ^a   Hayakawa, T ^a  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

Ki 67; PCNA; Pituitary adenoma; Tumour doubling time

Indexed keywords

CYCLINE; KI 67 ANTIGEN; MONOCLONAL ANTIBODY;

ADULT; AGED; ARTICLE; CANCER GROWTH; CANCER INVASION; CANCER RECURRENCE; CAVERNOUS SINUS; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; DIAGNOSTIC ACCURACY; FEMALE; HUMAN; HUMAN TISSUE; HYPOPHYSIS ADENOMA; IMAGE ANALYSIS; IMMUNOCYTOCHEMISTRY; MALE; MINIMAL RESIDUAL DISEASE; NUCLEAR MAGNETIC RESONANCE IMAGING; PREDICTION; PRIORITY JOURNAL; STAINING;

ADENOMA; ADULT; AGED; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; KI-67 ANTIGEN; MALE; MIDDLE AGED; PITUITARY NEOPLASMS; PROLIFERATING CELL NUCLEAR ANTIGEN; STAINING AND LABELING; TIME FACTORS;

EID: 0030480514     PISSN: 00016268     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01411125     Document Type: Article

References (37)

1. Anniko M, Holm L-E, Wersäll J (1983) Aggressive pituitary tumor growth. Arch Otorhinolaryngol 238: 53-62
2. Brown DC, Gatter KC (1990) Monoclonal antibody Ki-67: its use in histopathology. Histopathology 17: 489-503
3. Burger PC, Shibata T, Kleihues P (1986) The use of the monoclonal antibody Ki-67 in the identification of proliferating cells: application to surgical neuropathology. Am J Surg Pathol 10: 611-617
4. Cho KG, Hoshino T, Nagashima T, Murovic JA, Wilson CB (1986) Prediction of tumor doubling time in recurrent meningiomas. J Neurosurg 65: 790-794
5. Ciric I, Mikhael M, Stafford T, Lawson L, Garces R (1983) Transsphenoidal microsurgery of pituitary macroadenomas with long-term follow-up results. J Neurosurg 59: 395-401
6. Ebersold MJ, Quast LM, Laws ER, Scheithauer B, Randall RV (1986) Long-term results in transsphenoidal removal of nonfunctioniong pituitary adenomas. J Neurosurg 64: 713-719
7. Ekramullah SM, Saitoh Y, Ohnishi T, Arita N, Taki T, Hayakawa T (1995) Effects of bromocriptine on staining indices of Ki-67 and proliferating cell nuclear antigen, and nucleolar organizer region number in pituitary adenomas. Neurol Med Chir (Tokyo) 35: 221-226
8. Falini B, Canino S, Sacchi S, Ciani C, Martelli MF, Gerdes J, Stein H, Pileri S, Gobbi M, Fagioli M, Minelli O, Flenghi L (1988) Immunocytochemical evaluation of the percentage of proliferating cells in pathological bone marrow and peripheral blood samples with the Ki-67 and anti-bromo-deoxyuridine monoclonal antibodies. Br J Haematol 69: 311-320
9. Gerdes J, Becker MHG, Key G (1992) Immunohistological detection of tumour growth fraction (Ki-67 antigen) in formalin-fixed and routinely processed tissues. J Pathol 168: 85-87
10. Hall PA, Levison DA, Woods AL, Yu CC-W, Kellock DB, Watkins JA, Barnes DM, Gillett CE, Camplejohn R, Dover R, Waseem NH, Lane DP (1990) Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections: an index of cell proliferation with evidence of deregulated expression in some neoplasms. J Pathol 162: 285-294
11. Horvath E, Kovacs K, Killinger DW, Smyth HS, Platts ME, Singer W (1980) Silent corticotrophic adenomas of the pituitary gland. A histologic, immunocytologic and ultrastructural study. Am J Pathol 98: 617-638
12. Hsu DW, Hakim F, Biller BMK, Monte SDL, Zervas NT, Klibanski A, Hedley-Whyte ET (1993) Significance of proliferating cell nuclear antigen index in predicting pituitary adenoma recurrence. J Neurosurg 78: 753-761
13. Kamel OW, Franklin WA, Ringus JC, Meyer JS (1989) Thymidine labelling index and Ki-67 growth fraction in lesions of the breast. Am J Pathol 134: 107-113
14. Karamitopoulou E, Perentes E, Melachrinou M, Maraziotis T (1993) Proliferating cell nuclear antigen immunoreactivity in human central nervous system neoplasms. Acta Neuropathol 85: 316-322
15. Knosp E, Kitz K, Perneczky A (1989) Proliferation activity in pituitary adenomas: measurement by monoclonal antibody Ki67. Neurosurgery 25: 927-930
16. Landolt AM, Shibata T, Kleihues P (1987) Growth rate of human pituitary adenomas. J Neurosurg 67: 803-806
17. May PL, Broome JC, Lawry J, Buxton RA, Battersby RDE (1989) The prediction of recurrence in meningiomas: a flow cytometric study of paraffin-embedded archival material. J Neurosurg 71: 347-351
18. Nagashima T, Murovic JA, Hoshino T, Wilson CB, DeArmond SJ (1986) The proliferative potential of human pituitary tumors in situ. J Neurosurg 64: 588-593
19. Nishizaki T, Orita T, Furutani Y, Ikeyama Y, Aoki H, Sasaki K (1989) Flow-cytometric DNA analysis and immunohistochemical measurement of Ki-67 and BUdR labelling indices in human brain tumors. J Neurosurg 70: 379-384
20. Rowlands DC, Brown HE, Barber PC, Jones EL (1991) The effect of tissue fixation on immunostaining for proliferating cell nuclear antigen with the monoclonal antibody PC10. J Pathol 165: 356-357
21. Sabattini E, Gerdes J, Gherlinzoni F, Poggi S, Zucchini L, Melilli G, Grigioni F, Del Vecchio MT, Leoncini L, Falini B, Pileri SA (1993) Comparison between the monoclonal antibodies Ki-67 and PC10 in 125 malignant lymphomas. J Pathol 169: 397-403
22. Sasaki M, Matsumura K, Tsuji T, Shinozaki F, Takahashi M (1988) Relationship between labelling indices of Ki-67 and BrdUrd in human malignant tumors. Cancer 62: 989-993
23. Scheithauer BW, Kovacs KT, Laws ERJ, Randall RV (1986) Pathology of invasive pituitary tumours with special reference to functional classification. J Neurosurg 65: 733-744
24. Schiffer D, Chiò A, Giordana MT, Pezzulo T, Vigliani MC (1993) Proliferating cell nuclear antigen expression in brain tumors, and its prognostic role in ependymomas: an immunohistochemical study. Acta Neuropathol 85: 495-502
25. Schrape S, Jones DB, Wright DH (1987) A comparison of three methods for the determination of the growth fraction in non-Hodgkin's lymphoma. Br J Cancer 55: 283-286
26. Schwarting R. Gerdes J, Niehus J, Jaeschke L, Stein H (1986) Determination of the growth fraction in cell suspensions by flow cytometry using the monoclonal antibody Ki-67. J Immunol Methods 90: 65-70
27. Selman WR, Laws ERJ, Scheithauer BW, Carpenter SM (1986) The occurrence of dural invasion in pituitary adenomas. J Neurosurg 64: 402-407
28. Shibuya M, Saito F, Miwa T, Davis RL, Wilson CB, Hoshino T (1992) Histochemical study of pituitary adenomas with Ki67 and anti-DNA polymerase alpha monoclonal antibodies, bromodeoxyuridine labelling, and nuclear organizer region counts. Acta Neuropathol 84: 178-183
29. Silvestrini R, Costa A, Veneroni S, Del Bino G, Persici P (1988) Comparative analysis of different approaches to investigate cell kinetics. Cell Tissue Kinet 21: 123-131
30. Taki T, Ohnishi T, Arita N, Hiraga S, Saitoh Y, Izumoto S, Mori K, Hayakawa T (1994) Anti-proliferative effects of TNP-470 on human malignant glioma in vivo: potent inhibition of tumor angiogenesis. J Neurooncol 19: 251-258
31. Tubiana M, Pejovic MH, Koscielny S, Chavaudra N, Malaise E (1989) Growth rate, kinetics of tumor cell proliferation and long-term outcome in human breast cancer. Int J Cancer 44: 17-22
32. 3H]-thymidine labelling index and monoclonal antibody Ki-67 in non-Hodgkin's lymphomas. Hematol Oncol 6: 21-28
33. Walker RA, Camplejohn RS (1988) Comparison of monoclonal antibody Ki-67 reactivity with grade and DNA flow cytometry of breast carcinomas. Br J Cancer 57: 281-283
34. Wersto RP, Herz F, Gallagher RE, Koss LG ( 1988) Cell cycle-dependent reactivity with the monoclonal antibody Ki-67 during myeloid cell differentiation. Exp Cell Res 179: 79-88
35. Wolf HK, Dittrich KL (1992) Detection of proliferating cell nuclear antigen in diagnostic histopathology. J Histochem Cytochem 40: 1269-1273
36. Yamashita T, Kuwabara T (1983) Estimation of rate of growth of malignant brain tumors by computed tomography scanning. Surg Neurol 20: 464-470
37. Yu CC-W, Woods AL, Levison DA (1992) The assessment of cellular proliferation by immunohistochemistry: a review of currently available methods and their applications. Histochem J 24: 121-131