Effect of acetylsalicylic acid on metabolism and contractility in the ischemic reperfused heart

Japanese Circulation Journal

Volumn 60, Issue 12, 1996, Pages 961-971

  Kawabata, Hitoshi ^a   Sugiyama, Kazuyoshi ^a   Katori, Ryo ^a  

^a KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

31P NMR; Acetylsalicylic acid; High energy phosphate; Ischemia; Perfluorochemicals; Reperfusion

Indexed keywords

ACETYLSALICYLIC ACID; ADENOSINE TRIPHOSPHATE; CREATINE PHOSPHATE; PHOSPHATE;

ANIMAL TISSUE; ARTICLE; CELL PH; CORONARY ARTERY BLOOD FLOW; DRUG EFFECT; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE CONTRACTILITY; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; MALE; NONHUMAN; PHOSPHATE METABOLISM; RABBIT;

6-KETOPROSTAGLANDIN F1 ALPHA; ADENOSINE TRIPHOSPHATE; ANIMALS; ASPIRIN; C-REACTIVE PROTEIN; CORONARY VESSELS; ENERGY METABOLISM; HEART; HYDROGEN-ION CONCENTRATION; MUSCLE CONTRACTION; MUSCLE FIBERS; MYOCARDIAL ISCHEMIA; PERFUSION; PHOSPHATES; PLATELET AGGREGATION INHIBITORS; RABBITS; REPERFUSION INJURY; VENTRICULAR FUNCTION, LEFT; VENTRICULAR PRESSURE;

EID: 0030479373     PISSN: 00471828     EISSN: None     Source Type: Journal    
DOI: 10.1253/jcj.60.961     Document Type: Article

References (30)

1. Weiss HJ, Danese CA, Voleti CD: Prevention of experimentally induced arterial thrombosis by aspirin. Fed Proc 1970; 29: 381
2. Vane JR: Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nature 1971; 231: 232-235
3. Fields WS, Lemak NA, Frakowski RE, Hardy RJ: Controlled trial of aspirin in cerebral ischemia. Stroke 1977; 8: 301-316
4. The Canadian Cooperative Study Group: A randomized trial of aspirin and sulfinpyrazone in threatened stroke. N Engl J Med 1978; 299: 53-59
5. Klint CR, Knatterud GL, Stamler J, Meier P: Persantine-aspirin reinfarction study. Part II. Secondary coronary prevention with persantine and aspirin. J Am Coll Cardiol 1986; 7: 251-269
6. Steering Committee of the Physicians' Health Study Research Group: Final report on the aspirin component of the ongoing physicians' health study. N Engl J Med 1989; 321: 129-135
7. Ridker RM, Manson JE, Buring JE, Muller JE, Hennekcns CH: Circadian variation of acute myocardial infarction and the effect of low-dose aspirin in a randomized trial of physicians. Circulation 1990: 812: 897-902
8. Karmazyn M, Neely JR: Evidence for a direct protective effect of aspirin on the ischemic and reperfused heart. Circulation 1988; 78(Suppl II): 16
9. 31P nuclear magnetic resonance analysis of metabolite concentrations in Langendorff-perfused rabbit hearts. Biophys J 1985; 48: 803-813
10. 31P-NMR. Biochim Biophys Acta 1987; 927: 350-358
11. Kawabata H, Takada K, Katori R: Effect of methytprednisolone on metabolism and contractility in the stunned myocardium. Angiology 1995; 46: 895-904
12. Isoyama S, Apstein CS, Wexler LF, Grice WN, Lorell BH: Acute decrease in left ventricular diastolic chamber distensibility during stimulated angina in isolated hearts. Circ Res 1987; 61: 925-933
13. Jennings RB, Reimer KA: Biology of experimental, acute myocardial ischemia and infarction. In: Hearse DJ, editor. Enzymes in Cardiology-diagnosis and research: chapt 2. Chichester: John Wiley & Sons, 1979; 21-57
14. Jennings RB, Reimer KA, Hill ML, Mayer SE: Total ischemia in dog hearts, in vitro. Circ Res 1981; 49: 892-900
15. Reimer KA, Jennings RB, Hill ML: Total ischemia in dog hearts, in vitro. Circ Res 1981; 49: 901-911
16. Itoh K, Matsubara T, Nanki M, Nisimura K, Kambe T, Sugiyama S Ozawa T, Sakamoto N: Relationship between regional myocardial blood flow and tissue ATP content in acute ischemia. Jpn Heart J 1984; 25: 599-608
17. Lundsgaad-Hansen, P: Collective review surgical aspects of cardiac metabolism. Surg Gynecol Obstet 1966; 122: 1095-1099
18. Kubler W: Cardiac energy metabolism of congestive heart failure (in Japanese). Heart 1972; 4: 656-667
19. Marcus AJ: Aspirin and thromboembolism. A possible dilemma. N Engl J Med 1977; 297: 1284-1285
20. Packham MA: Mode of action of acetylsalicylic acid. New York: Raven Press, 1982; 63-82
21. Yoshida H, Tanaka S: Molecular pharmacology (in Japanese). Tokyo: Asakura Syoten, 1979; 401-415
22. Karmazyn M: Contribution of prostaglandins to reperfusion-induced ventricular failure in isolated rat hearts. Am J Physiol 1986; 251: H133-H140
23. Moschos CB, Haider B, Cruz CD Jr, Lyons MM, Regan TJ: Antiarrhythmic effects of aspirin during nonthrombotic coronary occlusion. Circulation 1987; 57: 681-684
24. Capurro NL, Marr KC, Aamodt R, Goldstein RE, Epstein SE: Aspirin-induced increase in collateral flow after acute coronary occlusion in dogs. Circulalion 1979; 59: 744-747
25. 2+ metabolism (in Japanese). Jpn J Clin Exp Med 1991; 68: 747-750
26. Alexander RW, Kent KM, Pisano JJ, Keiser HR, Cooper T: Regulation of postocclusive hyperemia by endogenously synthesized prostaglandins in the dog heart: J Clin Invest 1975; 55: 1174-1181
27. Moffat MP: Concentration-dependent effects of prostacyclin on the response of the isolated guinea pig heart to ischemia and reperfusion: Possible involvement of the slow inward current. J Pharmacol Exp Ther 1987; 242: 292-299
28. Moffat MP, Karmazyn M, Ferrier GR: Prostaglandins as key modulators of reperfusion-induced cardiac injury. Initial studies into possible mechanisms. In: Beamish RE, Panagia V, Dhalla NS. editors. Pathogenesis of stress - induced heart disease; chapt 27. Boston: Martinus Nijhoff, 1985; 320-332
29. Karmazyn M. A role for prostaglandins in reperfusion-induced myocardial injury? In: Dhalla NS, Hearse DJ. editors. Advances in myocardiology; vol 6. New York: Plenum, 1985; 429-436
30. Karmazyn M, Pierce GN, Williams S: Effect of nonsteroidal anti-inflammatory drugs on the hypoxic rat heart. J Pharmacol Exp Ther 1981; 218: 488-496