메뉴 건너뛰기




Volumn 23, Issue SUPPL. 4, 1996, Pages 15-21

Superantigene - Bedeutung als Sepsisinduktoren

Author keywords

Endotoxin; Enterotoxins; Immunosuppression; Septicaemia; Superantigen

Indexed keywords

BACTERIA (MICROORGANISMS); POSIBACTERIA; STAPHYLOCOCCUS; STREPTOCOCCUS PYOGENES;

EID: 0030478386     PISSN: 14245485     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (10)

References (52)
  • 2
    • 0342966463 scopus 로고
    • Neue Perspektiven zur Pathophysiologie der gram-positiven Sepsis: Bakerielle Superantigene lösen T-Lymphozytenabhängiges Lymphokinsyndrom aus
    • Heeg K, Miethke T, Wagner H: Neue Perspektiven zur Pathophysiologie der gram-positiven Sepsis: Bakerielle Superantigene lösen T-Lymphozytenabhängiges Lymphokinsyndrom aus. Dtsch Ärztebl 1995;92:A1177-A1180.
    • (1995) Dtsch Ärztebl , vol.92
    • Heeg, K.1    Miethke, T.2    Wagner, H.3
  • 3
    • 0026051892 scopus 로고
    • Gram-negative sepsis. Background, clinical features, and intervention
    • Bone RC: Gram-negative sepsis. Background, clinical features, and intervention. Chest 1991; 100:802-808.
    • (1991) Chest , vol.100 , pp. 802-808
    • Bone, R.C.1
  • 4
    • 0026989386 scopus 로고
    • Bacterial endotoxins
    • Rietschel ET, Brade H: Bacterial endotoxins. Sci Am 1992;267:54-61.
    • (1992) Sci Am , vol.267 , pp. 54-61
    • Rietschel, E.T.1    Brade, H.2
  • 5
    • 0026568118 scopus 로고
    • Cytokine production after intravenous or peritoneal gram-negative bacterial challenge in mice. Comparative protective efficacy of antibodies to tumor necrosis factor-alpha and to lipopolysaccharide
    • Zanetti G, Heumann D, Gerain J, Kohler J, Abbet P, Barras C, Lucas R, Glauser MP, Baumgartner JD: Cytokine production after intravenous or peritoneal gram-negative bacterial challenge in mice. Comparative protective efficacy of antibodies to tumor necrosis factor-alpha and to lipopolysaccharide. J Immunol 1992;148:1890-1897.
    • (1992) J Immunol , vol.148 , pp. 1890-1897
    • Zanetti, G.1    Heumann, D.2    Gerain, J.3    Kohler, J.4    Abbet, P.5    Barras, C.6    Lucas, R.7    Glauser, M.P.8    Baumgartner, J.D.9
  • 7
    • 0028824813 scopus 로고
    • The cell wall components peptidoglycan and lipoteichoic acid from Staphylococcus aureus act in synergy to cause shock and multiple organ failure
    • de Kimpe SJ, Kengatharan M, Thiemermann C, Vane JR: The cell wall components peptidoglycan and lipoteichoic acid from Staphylococcus aureus act in synergy to cause shock and multiple organ failure. Proc Natl Acad Sci USA 1995;92:10359-10363.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 10359-10363
    • De Kimpe, S.J.1    Kengatharan, M.2    Thiemermann, C.3    Vane, J.R.4
  • 8
    • 0028114530 scopus 로고
    • Soluble peptidoglycan-induced monokine production can be blocked by anti-CD 14 monoclonal antibodies and by lipid A partial structures
    • Weidemann B, Brade H, Rietschel ET, Dziarski R, Bazil V, Kusumoto S, Flad HD, Ulmer AJ: Soluble peptidoglycan-induced monokine production can be blocked by anti-CD 14 monoclonal antibodies and by lipid A partial structures. Infect Immun 1994;62:4709-4715.
    • (1994) Infect Immun , vol.62 , pp. 4709-4715
    • Weidemann, B.1    Brade, H.2    Rietschel, E.T.3    Dziarski, R.4    Bazil, V.5    Kusumoto, S.6    Flad, H.D.7    Ulmer, A.J.8
  • 9
    • 0028285885 scopus 로고
    • Gram-positive cell walls stimulate synthesis of tumor necrosis factor-alpha and interleukin-6 by human monocytes
    • Heumann D, Barras C, Severin A, Glauser MP, Tomasz A: Gram-positive cell walls stimulate synthesis of tumor necrosis factor-alpha and interleukin-6 by human monocytes. Infect Immun 1994;62:2715-2721.
    • (1994) Infect Immun , vol.62 , pp. 2715-2721
    • Heumann, D.1    Barras, C.2    Severin, A.3    Glauser, M.P.4    Tomasz, A.5
  • 10
    • 0027468145 scopus 로고
    • The biochemistry and cell biology of antigen processing and presentation
    • Germain RN, Margulies DH: The biochemistry and cell biology of antigen processing and presentation. Annu Rev Immunol 1993;11:403-450.
    • (1993) Annu Rev Immunol , vol.11 , pp. 403-450
    • Germain, R.N.1    Margulies, D.H.2
  • 11
    • 0022558694 scopus 로고
    • The antigen-specific, major histocompatibility complex-restricted receptor on T cells
    • Marrack P, Kappler J: The antigen-specific, major histocompatibility complex-restricted receptor on T cells. Adv Immunol 1986;38:1-30.
    • (1986) Adv Immunol , vol.38 , pp. 1-30
    • Marrack, P.1    Kappler, J.2
  • 12
    • 0002614118 scopus 로고
    • Antigen processing and presentation
    • Paul WE (ed): New York, Raven Press
    • Germain RN: Antigen processing and presentation; in Paul WE (ed): Fundamental Immunology. New York, Raven Press, 1993, pp 629-675.
    • (1993) Fundamental Immunology , pp. 629-675
    • Germain, R.N.1
  • 13
    • 0023921344 scopus 로고
    • T cell stimulation by staphylococcal enterotoxins. Clonally variable response and requirement for major histocompatibility complex class II molecules on accessory or target cells
    • Fleischer B, Schrezenmeier H: T cell stimulation by staphylococcal enterotoxins. Clonally variable response and requirement for major histocompatibility complex class II molecules on accessory or target cells. J Exp Med 1988;167:1697-1707.
    • (1988) J Exp Med , vol.167 , pp. 1697-1707
    • Fleischer, B.1    Schrezenmeier, H.2
  • 15
    • 0025898690 scopus 로고
    • Superantigens: Mechanism of T-cell stimulation and role in immune responses
    • Herman A, Kappler JW, Marrack P, Pullen AM: Superantigens: Mechanism of T-cell stimulation and role in immune responses. Annu Rev Immunol 1991;9:745-772.
    • (1991) Annu Rev Immunol , vol.9 , pp. 745-772
    • Herman, A.1    Kappler, J.W.2    Marrack, P.3    Pullen, A.M.4
  • 16
    • 0025018298 scopus 로고
    • Superantigens interact with MHC class II molecules outside of the antigen groove
    • Dellabona P, Peccoud J, Kappler JW, Marrack P, Benoist C, Mathis D: Superantigens interact with MHC class II molecules outside of the antigen groove. Cell 1990;62:1115-1121.
    • (1990) Cell , vol.62 , pp. 1115-1121
    • Dellabona, P.1    Peccoud, J.2    Kappler, J.W.3    Marrack, P.4    Benoist, C.5    Mathis, D.6
  • 17
    • 0025090852 scopus 로고
    • HLA-DR alleles differ in their ability to present staphylococcal enterotoxins to T cells
    • Herman A, Croteau G, Sekaly RP, Kappler JW, Marrack P: HLA-DR alleles differ in their ability to present staphylococcal enterotoxins to T cells. J Exp Med 1990;172:709-717.
    • (1990) J Exp Med , vol.172 , pp. 709-717
    • Herman, A.1    Croteau, G.2    Sekaly, R.P.3    Kappler, J.W.4    Marrack, P.5
  • 18
    • 0024577093 scopus 로고
    • The V beta-specific superantigen staphylococcal enterotoxin B: Stimulation of mature T cells and clonal deletion in neonatal mice
    • White J, Herman A, Pullen AM, Kubo RT, Kappler JW, Marrack P: The V beta-specific superantigen staphylococcal enterotoxin B: Stimulation of mature T cells and clonal deletion in neonatal mice. Cell 1989;56:27-35.
    • (1989) Cell , vol.56 , pp. 27-35
    • White, J.1    Herman, A.2    Pullen, A.M.3    Kubo, R.T.4    Kappler, J.W.5    Marrack, P.6
  • 19
    • 0028010031 scopus 로고
    • Identification of two binding sites in staphylococcal enterotoxin B that confer specificity for TCR Vß gene products
    • Hayball JD, Robinson JH, O'Hehir RE, Verhoef A, Lamb JR, Lake RA: Identification of two binding sites in staphylococcal enterotoxin B that confer specificity for TCR Vß gene products. Int Immunol 1994;6:199-211.
    • (1994) Int Immunol , vol.6 , pp. 199-211
    • Hayball, J.D.1    Robinson, J.H.2    O'Hehir, R.E.3    Verhoef, A.4    Lamb, J.R.5    Lake, R.A.6
  • 20
    • 0026180579 scopus 로고
    • Murine CD4+ and CD8+ T cells are activated by the superantigen (SA) staphylococcal enterotoxin B (SEB) and exhibit MHC-unrestricted cytotoxicity
    • Miethke T, Bendigs S, Bader P, Wagner H, Heeg K: Murine CD4+ and CD8+ T cells are activated by the superantigen (SA) staphylococcal enterotoxin B (SEB) and exhibit MHC-unrestricted cytotoxicity. Int J Med Microbiol 1991;275:264-268.
    • (1991) Int J Med Microbiol , vol.275 , pp. 264-268
    • Miethke, T.1    Bendigs, S.2    Bader, P.3    Wagner, H.4    Heeg, K.5
  • 21
    • 0027982108 scopus 로고
    • Toxoplasma gondii possesses a superantigen activity that selectively expands murine T cell receptor Vβ5-bearing CD8+ lymphocytes
    • Denkers EY, Caspar P, Sher A: Toxoplasma gondii possesses a superantigen activity that selectively expands murine T cell receptor Vβ5-bearing CD8+ lymphocytes. J Exp Med 1994;180:985-994.
    • (1994) J Exp Med , vol.180 , pp. 985-994
    • Denkers, E.Y.1    Caspar, P.2    Sher, A.3
  • 23
    • 0028796908 scopus 로고
    • Frequency of toxic shock syndrome toxin- and enterotoxin-producing clinical isolates of Staphylococcus aureus
    • Lehn N, Schaller E, Wagner H, Krönke M: Frequency of toxic shock syndrome toxin- and enterotoxin-producing clinical isolates of Staphylococcus aureus. Eur J Clin Microbiol Infect Dis 1995;14:43-46.
    • (1995) Eur J Clin Microbiol Infect Dis , vol.14 , pp. 43-46
    • Lehn, N.1    Schaller, E.2    Wagner, H.3    Krönke, M.4
  • 24
    • 0023899331 scopus 로고
    • Toxic shock syndrome toxin 1 as an inducer of human tumor necrosis factors and gamma interferon
    • Jupin C, Anderson S, Damais C, Alouf JE, Parant M: Toxic shock syndrome toxin 1 as an inducer of human tumor necrosis factors and gamma interferon. J Exp Med 1988;167:752-761.
    • (1988) J Exp Med , vol.167 , pp. 752-761
    • Jupin, C.1    Anderson, S.2    Damais, C.3    Alouf, J.E.4    Parant, M.5
  • 26
    • 0027321570 scopus 로고
    • Pathogenesis of the toxic shock syndrome: T cell mediated lethal shock caused by the superantigen TSST-1
    • Miethke T, Duschek K, Wahl C, Heeg K, Wagner H: Pathogenesis of the toxic shock syndrome: T cell mediated lethal shock caused by the superantigen TSST-1. Eur J Immunol 1993;23:1494-1500.
    • (1993) Eur J Immunol , vol.23 , pp. 1494-1500
    • Miethke, T.1    Duschek, K.2    Wahl, C.3    Heeg, K.4    Wagner, H.5
  • 28
    • 0030321931 scopus 로고    scopus 로고
    • Superantigen-mediated lethal shock: The functional state of ligand-reactive T cells
    • Heeg K, Miethke T, Wagner H: Superantigen-mediated lethal shock: The functional state of ligand-reactive T cells. Curr Top Microbiol Immunol 1996;216:83-100.
    • (1996) Curr Top Microbiol Immunol , vol.216 , pp. 83-100
    • Heeg, K.1    Miethke, T.2    Wagner, H.3
  • 29
    • 0027138096 scopus 로고
    • Bacterial superantigens induce rapid and TCR Vβ-selective downregulation of L-selectin (gp90-Mell4) in vivo
    • Miethke T, Wahl C, Holzmann B, Heeg K, Wagner H: Bacterial superantigens induce rapid and TCR Vβ-selective downregulation of L-selectin (gp90-Mell4) in vivo. J Immunol 1993;151:6777-6782.
    • (1993) J Immunol , vol.151 , pp. 6777-6782
    • Miethke, T.1    Wahl, C.2    Holzmann, B.3    Heeg, K.4    Wagner, H.5
  • 30
    • 0028171332 scopus 로고
    • Superantigen-induced anergy of Vβ8+ CD4+ T cells induces functional but nonproliferative T cells in vivo
    • Gaus H, Miethke T, Wagner H, Heeg K: Superantigen-induced anergy of Vβ8+ CD4+ T cells induces functional but nonproliferative T cells in vivo. Immunology 1994;83:333-340.
    • (1994) Immunology , vol.83 , pp. 333-340
    • Gaus, H.1    Miethke, T.2    Wagner, H.3    Heeg, K.4
  • 31
    • 0026596020 scopus 로고
    • T cell-mediated lethal shock triggered in mice by the superantigen staphylococcal enterotoxin B: Critical role of tumor necrosis factor
    • Miethke T, Wahl C, Heeg K, Echtenacher B, Krammer PH, Wagner H: T cell-mediated lethal shock triggered in mice by the superantigen staphylococcal enterotoxin B: Critical role of tumor necrosis factor. J Exp Med 1992;175:91-98.
    • (1992) J Exp Med , vol.175 , pp. 91-98
    • Miethke, T.1    Wahl, C.2    Heeg, K.3    Echtenacher, B.4    Krammer, P.H.5    Wagner, H.6
  • 32
    • 0027465502 scopus 로고
    • Glucocorticoid-mediated control of the activation and clonal deletion of peripheral T cells in vivo
    • Gonzalo JA, Gonzalez-Garcia A, Martinez C, Kroemer G: Glucocorticoid-mediated control of the activation and clonal deletion of peripheral T cells in vivo. J Exp Med 1993;177:1239-1246.
    • (1993) J Exp Med , vol.177 , pp. 1239-1246
    • Gonzalo, J.A.1    Gonzalez-Garcia, A.2    Martinez, C.3    Kroemer, G.4
  • 34
    • 0000352873 scopus 로고
    • Galactosamine-induced sensitization of the lethal effects of endotoxin
    • Galanos C, Freudenberg MA, Reutter W: Galactosamine-induced sensitization of the lethal effects of endotoxin. Proc Natl Acad Sci USA 1979;76:5939-5943.
    • (1979) Proc Natl Acad Sci USA , vol.76 , pp. 5939-5943
    • Galanos, C.1    Freudenberg, M.A.2    Reutter, W.3
  • 35
    • 0025096424 scopus 로고
    • Selective anergy of V beta 8+, CD4+ T cells in Staphylococcus enterotoxin B-primed mice
    • Kawabe Y, Ochi A: Selective anergy of V beta 8+, CD4+ T cells in Staphylococcus enterotoxin B-primed mice. J Exp Med 1990;172:1065-1070.
    • (1990) J Exp Med , vol.172 , pp. 1065-1070
    • Kawabe, Y.1    Ochi, A.2
  • 36
    • 0028060199 scopus 로고
    • Exogenous superantigens acutely trigger distinct levels of peripheral T cell tolerance/immunosuppression: Dose-response relationship
    • Miethke T, Wahl C, Gaus H, Heeg K, Wagner H: Exogenous superantigens acutely trigger distinct levels of peripheral T cell tolerance/immunosuppression: Dose-response relationship. Eur J Immunol 1994;24:1893-1902.
    • (1994) Eur J Immunol , vol.24 , pp. 1893-1902
    • Miethke, T.1    Wahl, C.2    Gaus, H.3    Heeg, K.4    Wagner, H.5
  • 37
    • 0025223870 scopus 로고
    • Induction of specific clonal anergy in human T lymphocytes by Staphylococcus aureus enterotoxins
    • O'Hehir RE, Lamb JR: Induction of specific clonal anergy in human T lymphocytes by Staphylococcus aureus enterotoxins. Proc Natl Acad Sci USA 1990;87:8884-8888.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 8884-8888
    • O'Hehir, R.E.1    Lamb, J.R.2
  • 38
    • 0025096425 scopus 로고
    • In vivo induction of anergy in peripheral V beta 8+ T cells by staphylococcal enterotoxin B
    • Rellahan BL, Jones LA, Kruisbeek AM, Fry AM, Matis LA: In vivo induction of anergy in peripheral V beta 8+ T cells by staphylococcal enterotoxin B. J Exp Med 1990;172:1091-1100.
    • (1990) J Exp Med , vol.172 , pp. 1091-1100
    • Rellahan, B.L.1    Jones, L.A.2    Kruisbeek, A.M.3    Fry, A.M.4    Matis, L.A.5
  • 39
    • 0027221160 scopus 로고
    • Induction of unresponsiveness to the superantigen staphylococcal enterotoxin B: Cyclosporin A resistant split unresponsiveness unfolds in vivo without preceding clonal expansion
    • Heeg K, Bendigs S, Miethke T, Wagner H: Induction of unresponsiveness to the superantigen staphylococcal enterotoxin B: Cyclosporin A resistant split unresponsiveness unfolds in vivo without preceding clonal expansion. Int Immunol 1993;5:929-937.
    • (1993) Int Immunol , vol.5 , pp. 929-937
    • Heeg, K.1    Bendigs, S.2    Miethke, T.3    Wagner, H.4
  • 40
    • 0027308742 scopus 로고
    • The fate of anergic T cells in vivo
    • Migita K, Ochi A: The fate of anergic T cells in vivo. J Immunol 1993;150:763-770.
    • (1993) J Immunol , vol.150 , pp. 763-770
    • Migita, K.1    Ochi, A.2
  • 41
    • 0027429426 scopus 로고
    • Toxicily of staphylococcal enterotoxins potentiated by lipopolysaccharide: Major histocompatibility complex class II molecule dependency and cytokine release
    • Stiles BG, Bavari S, Krakauer T, Ulrich RG: Toxicily of staphylococcal enterotoxins potentiated by lipopolysaccharide: Major histocompatibility complex class II molecule dependency and cytokine release. Infect Immun 1993;61:5333-5338.
    • (1993) Infect Immun , vol.61 , pp. 5333-5338
    • Stiles, B.G.1    Bavari, S.2    Krakauer, T.3    Ulrich, R.G.4
  • 43
    • 0027330893 scopus 로고
    • IFN-gamma and lipopolysaccharide differentially modulate expression of tumor necrosis factor receptor messenger RNA in murine peritoneal macrophages
    • Tannenbaum CS, Major JA, Hamilton TA: IFN-gamma and lipopolysaccharide differentially modulate expression of tumor necrosis factor receptor messenger RNA in murine peritoneal macrophages. J Immunol 1993;151:6833-6839.
    • (1993) J Immunol , vol.151 , pp. 6833-6839
    • Tannenbaum, C.S.1    Major, J.A.2    Hamilton, T.A.3
  • 44
    • 0027982098 scopus 로고
    • Interleukin 12, interferon gamma and tumor necrosis factor alpha are the key mediators of the generalized Schwartzman reaction
    • Ozmen L, Pericin M, Hakimi J, Chizzonite RA, Wysocka M, Trinchieri G, Gately M, Garotta G: Interleukin 12, interferon gamma and tumor necrosis factor alpha are the key mediators of the generalized Schwartzman reaction. J Exp Med 1994;180:907-915.
    • (1994) J Exp Med , vol.180 , pp. 907-915
    • Ozmen, L.1    Pericin, M.2    Hakimi, J.3    Chizzonite, R.A.4    Wysocka, M.5    Trinchieri, G.6    Gately, M.7    Garotta, G.8
  • 45
    • 0028987562 scopus 로고
    • Interleukin-12 is required for interferon-γ production and lethality in lipopolysaccharide-induced shock in mice
    • Wysocka M, Kubin M, Vieira LQ, Ozmen L, Garotta G, Scott P, Trinchieri G: Interleukin-12 is required for interferon-γ production and lethality in lipopolysaccharide-induced shock in mice. Eur J Immunol 1995;25:672-676.
    • (1995) Eur J Immunol , vol.25 , pp. 672-676
    • Wysocka, M.1    Kubin, M.2    Vieira, L.Q.3    Ozmen, L.4    Garotta, G.5    Scott, P.6    Trinchieri, G.7
  • 46
    • 0028170178 scopus 로고
    • Protection by γl-acid glycoprotein against tumor necrosis factor-induced lethality
    • Libert C, Brouckaert P, Fiers W: Protection by γl-acid glycoprotein against tumor necrosis factor-induced lethality. J Exp Med 1994;180:1571-1575.
    • (1994) J Exp Med , vol.180 , pp. 1571-1575
    • Libert, C.1    Brouckaert, P.2    Fiers, W.3
  • 47
    • 0029029313 scopus 로고
    • Inhibition of TNF-triggering activity of lipopolysaccharide by a proteinaceous factor from normal mouse liver
    • Satoh M, Matsumura T, Nakamoto M, Yamazaki M: Inhibition of TNF-triggering activity of lipopolysaccharide by a proteinaceous factor from normal mouse liver. J Immunol 1995;155:877-885.
    • (1995) J Immunol , vol.155 , pp. 877-885
    • Satoh, M.1    Matsumura, T.2    Nakamoto, M.3    Yamazaki, M.4
  • 48
    • 0027433633 scopus 로고
    • Interleukin 10 protects mice against staphylococcal enterotoxin B-induced lethal shock
    • Bean AG, Freiberg RA, Andrade S, Menon S, Zlotnik A: Interleukin 10 protects mice against staphylococcal enterotoxin B-induced lethal shock. Infect Immun 1993;61:4937-4939.
    • (1993) Infect Immun , vol.61 , pp. 4937-4939
    • Bean, A.G.1    Freiberg, R.A.2    Andrade, S.3    Menon, S.4    Zlotnik, A.5
  • 50
    • 0028906220 scopus 로고
    • Mechanism of endotoxin desensitization: Involvement of interleukin 10 and transforming growth factor β
    • Randow F, Syrbe U, Meisel C, Krausen D, Zukkermann H, Platzer C, Volk HD: Mechanism of endotoxin desensitization: Involvement of interleukin 10 and transforming growth factor β. J Exp Med 1995;181:1887-1892.
    • (1995) J Exp Med , vol.181 , pp. 1887-1892
    • Randow, F.1    Syrbe, U.2    Meisel, C.3    Krausen, D.4    Zukkermann, H.5    Platzer, C.6    Volk, H.D.7
  • 51
    • 0029164394 scopus 로고
    • Role of the hypothalamus-pituitary-adrenal axis in the regulation of TNF production in mice. Effect of stress and inhibition of endogenous glucocorticoids
    • Fantuzzi G, di Santo E, Sacco S, Benigni F, Ghezzi P: Role of the hypothalamus-pituitary-adrenal axis in the regulation of TNF production in mice. Effect of stress and inhibition of endogenous glucocorticoids. J Immunol 1995;155:3552-3555.
    • (1995) J Immunol , vol.155 , pp. 3552-3555
    • Fantuzzi, G.1    Di Santo, E.2    Sacco, S.3    Benigni, F.4    Ghezzi, P.5
  • 52
    • 0028867899 scopus 로고
    • Immunosuppression by glucocorticoids: Inhibition of NFκB activity through induction of lκB synthesis
    • Auphan N, DiDonato JA, Rosette C, Helmberg A, Karin M: Immunosuppression by glucocorticoids: Inhibition of NFκB activity through induction of lκB synthesis. Science 1995;270:286-290.
    • (1995) Science , vol.270 , pp. 286-290
    • Auphan, N.1    DiDonato, J.A.2    Rosette, C.3    Helmberg, A.4    Karin, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.