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Volumn 9, Issue 6, 1996, Pages 438-448

Advances in the treatment of diabetes mellitus in the elderly: Development of insulin analogues

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; INSULIN DERIVATIVE; INSULIN GLARGINE; INSULIN LISPRO; UNCLASSIFIED DRUG;

EID: 0030478225     PISSN: 1170229X     EISSN: None     Source Type: Journal    
DOI: 10.2165/00002512-199609060-00006     Document Type: Review
Times cited : (10)

References (65)
  • 1
    • 0004207691 scopus 로고
    • Chicago: The University of Chicago Press
    • Bliss M. The discovery of insulin. Chicago: The University of Chicago Press, 1982
    • (1982) The Discovery of Insulin
    • Bliss, M.1
  • 2
    • 0028874605 scopus 로고
    • The pharmacological treatment of hyperglycemia in NIDDM
    • American Diabetes Association. The pharmacological treatment of hyperglycemia in NIDDM. Diabetes Care 1995; 18: 1510-8
    • (1995) Diabetes Care , vol.18 , pp. 1510-1518
  • 3
    • 0025078913 scopus 로고
    • Monomeric insulins and their experimental and clinical implications
    • Brange J, Owens DR, Kang S, et al. Monomeric insulins and their experimental and clinical implications. Diabetes Care 1990; 13: 923-54
    • (1990) Diabetes Care , vol.13 , pp. 923-954
    • Brange, J.1    Owens, D.R.2    Kang, S.3
  • 4
    • 0022497629 scopus 로고
    • Efficiency of pulsatile versus continuous insulin administration on hepatic glucose utilization in type I diabetic humans
    • Bratusch-Marrain PR, Komjati M, Waldhaust WK. Efficiency of pulsatile versus continuous insulin administration on hepatic glucose utilization in type I diabetic humans. Diabetes 1986; 35: 922-6
    • (1986) Diabetes , vol.35 , pp. 922-926
    • Bratusch-Marrain, P.R.1    Komjati, M.2    Waldhaust, W.K.3
  • 5
    • 0021751981 scopus 로고
    • Diminished beta-cell secretory capacity in patients with non-insulin dependent DM
    • Ward WK, Bolgiano DC, McKnight B, et al. Diminished beta-cell secretory capacity in patients with non-insulin dependent DM. J Clin Invest 1984; 74: 1318-28
    • (1984) J Clin Invest , vol.74 , pp. 1318-1328
    • Ward, W.K.1    Bolgiano, D.C.2    McKnight, B.3
  • 6
    • 0023838435 scopus 로고
    • The disposal of an oral glucose load in patients with non-insulin-dependent diabetes
    • Ferrannini E, Simonson DC, Katz LD, et al. The disposal of an oral glucose load in patients with non-insulin-dependent diabetes. Metabolism 1988; 37: 79-85
    • (1988) Metabolism , vol.37 , pp. 79-85
    • Ferrannini, E.1    Simonson, D.C.2    Katz, L.D.3
  • 7
    • 0025966024 scopus 로고
    • Contribution to post-prandial hyperglycemia and effect on initial splanchnic glucose clearance of hepatic glucose cycling in glucose-intolerant or NIDDM patients
    • Butler PC, Rizza RA. Contribution to post-prandial hyperglycemia and effect on initial splanchnic glucose clearance of hepatic glucose cycling in glucose-intolerant or NIDDM patients. Diabetes 1991; 40: 73-81
    • (1991) Diabetes , vol.40 , pp. 73-81
    • Butler, P.C.1    Rizza, R.A.2
  • 8
    • 0024216182 scopus 로고
    • Physiological importance of deficiency in early prandial insulin secretion in non-insulin-dependent diabetes
    • Bruce DG, Chisholm DJ, Storlein LH, et al. Physiological importance of deficiency in early prandial insulin secretion in non-insulin-dependent diabetes. Diabetes 1988; 37: 736-44
    • (1988) Diabetes , vol.37 , pp. 736-744
    • Bruce, D.G.1    Chisholm, D.J.2    Storlein, L.H.3
  • 9
    • 0021246697 scopus 로고
    • Pathophysiology of beta-cell failure after prolonged remission in insulin-dependent DM
    • Drucker D, Zinman B. Pathophysiology of beta-cell failure after prolonged remission in insulin-dependent DM. Diabetes Care 1984; 1: 83-7
    • (1984) Diabetes Care , vol.1 , pp. 83-87
    • Drucker, D.1    Zinman, B.2
  • 10
    • 0021845962 scopus 로고
    • Meal stimulated C-peptide response and insulin antibodies in type I diabetic subjects and non-diabetic siblings and characterized by HLA DR antigens
    • Hoogwerf BJ, Rich SJ, Barbosa JJ. Meal stimulated C-peptide response and insulin antibodies in type I diabetic subjects and non-diabetic siblings and characterized by HLA DR antigens. Diabetes 1985; 34: 440-5
    • (1985) Diabetes , vol.34 , pp. 440-445
    • Hoogwerf, B.J.1    Rich, S.J.2    Barbosa, J.J.3
  • 11
    • 0026701406 scopus 로고
    • C-peptide response to meal challenge in non-diabetic and diabetic adults living in Wadena, Minnesota
    • Bushhouse SA, Goetz FC, Jacobs DR, et al. C-peptide response to meal challenge in non-diabetic and diabetic adults living in Wadena, Minnesota. Diabetes Care 1992; 15: 1335-47
    • (1992) Diabetes Care , vol.15 , pp. 1335-1347
    • Bushhouse, S.A.1    Goetz, F.C.2    Jacobs, D.R.3
  • 12
    • 0026573403 scopus 로고
    • Association between stimulated plasma C-peptide and age: The Wadena City Health Study
    • French LR, Goetz FC, Martinez AM, et al. Association between stimulated plasma C-peptide and age: the Wadena City Health Study. J Am Geriatr Soc 1992; 40: 309-15
    • (1992) J Am Geriatr Soc , vol.40 , pp. 309-315
    • French, L.R.1    Goetz, F.C.2    Martinez, A.M.3
  • 13
    • 0027972684 scopus 로고
    • [Lys(B28), Pro(B29)] - human insulin: A rapidly absorbed analogue of human insulin
    • Howey DC, Bowsher RR, Brunelle RL, et al. [Lys(B28), Pro(B29)] - human insulin: a rapidly absorbed analogue of human insulin. Diabetes 1994; 43: 396-402
    • (1994) Diabetes , vol.43 , pp. 396-402
    • Howey, D.C.1    Bowsher, R.R.2    Brunelle, R.L.3
  • 14
    • 0026058684 scopus 로고
    • In vitro and in vivo potency of insulin analogues designed for clinical use
    • Volund AA, Brange J, Drejer K, et al. In vitro and in vivo potency of insulin analogues designed for clinical use. Diabet Med 1991; 8: 839-47
    • (1991) Diabet Med , vol.8 , pp. 839-847
    • Volund, A.A.1    Brange, J.2    Drejer, K.3
  • 15
    • 0025859920 scopus 로고
    • Comparison of subcutaneous soluble human insulin and insulin analogues (AspB9, GluB27; AspB10; AspB28) on meal-related plasma glucose excursions in type I diabetic subjects
    • Kang S, Creagh FM, Pteres JR, et al. Comparison of subcutaneous soluble human insulin and insulin analogues (AspB9, GluB27; AspB10; AspB28) on meal-related plasma glucose excursions in type I diabetic subjects. Diabetes Care 1991; 14: 571-7
    • (1991) Diabetes Care , vol.14 , pp. 571-577
    • Kang, S.1    Creagh, F.M.2    Pteres, J.R.3
  • 16
    • 0023918646 scopus 로고
    • Soluble, prolonged-acting insulin derivatives: III. Degree of protraction, crystallizability and chemical stability of insulins substituted in positions A21, B13, B23, B27 and B30
    • Markussen J, Diers I, Hougaard P, et al. Soluble, prolonged-acting insulin derivatives: III. Degree of protraction, crystallizability and chemical stability of insulins substituted in positions A21, B13, B23, B27 and B30. Protein Eng 1988; 2: 157-66
    • (1988) Protein Eng , vol.2 , pp. 157-166
    • Markussen, J.1    Diers, I.2    Hougaard, P.3
  • 17
    • 0026680808 scopus 로고
    • Intravenous infusion of diarginylinsulin, as insulin analogue: Effects on glucose turnover and lipid levels in insulin-treated type II diabetic patients
    • Monti LD, Poma R, Caumo I, et al. Intravenous infusion of diarginylinsulin, as insulin analogue: effects on glucose turnover and lipid levels in insulin-treated type II diabetic patients. Metabolism 1992; 41: 540-4
    • (1992) Metabolism , vol.41 , pp. 540-544
    • Monti, L.D.1    Poma, R.2    Caumo, I.3
  • 18
    • 0027231640 scopus 로고
    • Action profile of the rapid acting insulin analogue: Human insulin B28asp
    • Heinemann L, Heise T, Jornegsen LN, et al. Action profile of the rapid acting insulin analogue: human insulin B28asp. Diabet Med 1993; 10: 535-9
    • (1993) Diabet Med , vol.10 , pp. 535-539
    • Heinemann, L.1    Heise, T.2    Jornegsen, L.N.3
  • 19
    • 0001468029 scopus 로고
    • Soluble, prolonged-acting insulin derivatives: I. Degree of protraction and crystallizability of insulins substituted in the termini of the B-chain
    • Markussen J, Hougaard P, Ribel U, et al. Soluble, prolonged-acting insulin derivatives: I. Degree of protraction and crystallizability of insulins substituted in the termini of the B-chain. Protein Eng 1987; 1: 205-13
    • (1987) Protein Eng , vol.1 , pp. 205-213
    • Markussen, J.1    Hougaard, P.2    Ribel, U.3
  • 20
    • 0028446498 scopus 로고
    • Semisynthetic insulin analogues modified in positions B24, B25, and B29
    • Svoboda I, Brandenburg D, Barth T, et al. Semisynthetic insulin analogues modified in positions B24, B25, and B29. Biol Chem Hoppe Seyler 1994; 375 (6): 373-8
    • (1994) Biol Chem Hoppe Seyler , vol.375 , Issue.6 , pp. 373-378
    • Svoboda, I.1    Brandenburg, D.2    Barth, T.3
  • 21
    • 0022536102 scopus 로고
    • Receptor binding and negative cooperativety of mutant insulin. [leuA3] - insulin
    • Kobayashi M, Takata Y, Ishibashi O, et al. Receptor binding and negative cooperativety of mutant insulin. [leuA3] - insulin. Biochem Biophys Res Commun 1986; 137: 250-7
    • (1986) Biochem Biophys Res Commun , vol.137 , pp. 250-257
    • Kobayashi, M.1    Takata, Y.2    Ishibashi, O.3
  • 23
    • 0025218963 scopus 로고
    • Insulin-like growth factor-1 at physiological concentrations is a potent inhibitor of insulin secretion
    • Leahy J, Vandekerkhove KM. Insulin-like growth factor-1 at physiological concentrations is a potent inhibitor of insulin secretion. Endocrinology 1990; 126: 1593-8
    • (1990) Endocrinology , vol.126 , pp. 1593-1598
    • Leahy, J.1    Vandekerkhove, K.M.2
  • 24
    • 0026740350 scopus 로고
    • Effects of insulin-like growth factor-1 on glucose tolerance, insulin levels and insulin secretion
    • Zenobi PD, Graf S, Ursprung H, et al. Effects of insulin-like growth factor-1 on glucose tolerance, insulin levels and insulin secretion. J Clin Invest 1992; 89: 1908-13
    • (1992) J Clin Invest , vol.89 , pp. 1908-1913
    • Zenobi, P.D.1    Graf, S.2    Ursprung, H.3
  • 25
    • 0027074505 scopus 로고
    • Insulin-like growth factor-1 improves glucose and lipid metabolism in type 2 diabetes mellitus
    • Zenobi PD, Jaeggi-Groisman SE, Riesen WF, et al. Insulin-like growth factor-1 improves glucose and lipid metabolism in type 2 diabetes mellitus. J Clin Invest 1992; 90: 2234-41
    • (1992) J Clin Invest , vol.90 , pp. 2234-2241
    • Zenobi, P.D.1    Jaeggi-Groisman, S.E.2    Riesen, W.F.3
  • 26
    • 0027278180 scopus 로고
    • Improvement of lipid profile in type 2 (non-insulin-dependent) diabetes mellitus by insulin-like growth factor
    • Zenobi PD, Holzmann P, Glatz Y, et al. Improvement of lipid profile in type 2 (non-insulin-dependent) diabetes mellitus by insulin-like growth factor. Diabetologia 1993; 36: 465-9
    • (1993) Diabetologia , vol.36 , pp. 465-469
    • Zenobi, P.D.1    Holzmann, P.2    Glatz, Y.3
  • 27
    • 0027932692 scopus 로고
    • Metabolic and therapeutic effects of insulin-like growth factor
    • Froesch ER, Zenobi PD, Hussain M, Metabolic and therapeutic effects of insulin-like growth factor. Hormone Res 1994; 42: 66-71
    • (1994) Hormone Res , vol.42 , pp. 66-71
    • Froesch, E.R.1    Zenobi, P.D.2    Hussain, M.3
  • 28
    • 0024442007 scopus 로고
    • Mechanism of IGF-1-stimulated glucose transport in human adipocytes: Demonstration of specific IGF-1 receptors not involved with glucose transport
    • Sinha MK, Buchanan C, Leggett N, et al. Mechanism of IGF-1-stimulated glucose transport in human adipocytes: demonstration of specific IGF-1 receptors not involved with glucose transport. Diabetes 1989; 38: 1217-25
    • (1989) Diabetes , vol.38 , pp. 1217-1225
    • Sinha, M.K.1    Buchanan, C.2    Leggett, N.3
  • 29
    • 0025894102 scopus 로고
    • Binding and biological effects of insulin, insulin analogues and insulin-like growth factors in rat aortic smooth muscle cells: Comparison of maximal growth promoting activities
    • Bornfeldt KE, Gidlof RA, Wasteson A, et al. Binding and biological effects of insulin, insulin analogues and insulin-like growth factors in rat aortic smooth muscle cells: comparison of maximal growth promoting activities. Diabelologia 1991; 34: 307-13
    • (1991) Diabelologia , vol.34 , pp. 307-313
    • Bornfeldt, K.E.1    Gidlof, R.A.2    Wasteson, A.3
  • 30
    • 0026343661 scopus 로고
    • Association of elevated IGF-1 levels with increased retinopathy in late-onset diabetes
    • Dills DG, Moss SE, Klein R, et al. Association of elevated IGF-1 levels with increased retinopathy in late-onset diabetes. Diabetes 1991; 40: 1725-30
    • (1991) Diabetes , vol.40 , pp. 1725-1730
    • Dills, D.G.1    Moss, S.E.2    Klein, R.3
  • 31
    • 0027097641 scopus 로고
    • The bioactivity of insulin analogues from in vitro receptor bindine to in vivo glucose uptake
    • Drejer K. The bioactivity of insulin analogues from in vitro receptor bindine to in vivo glucose uptake. Diabetes Metab Rev 1992; 8: 259-86
    • (1992) Diabetes Metab Rev , vol.8 , pp. 259-286
    • Drejer, K.1
  • 32
    • 2642629923 scopus 로고
    • Treatment of 722 patients with type II diabetes with insulin lispro in a 6 month crossover study
    • Vignati L, Brunelle RL. Treatment of 722 patients with type II diabetes with insulin lispro in a 6 month crossover study [abstract]. Diabetes 1995; 44 Suppl. 840: 229A
    • (1995) Diabetes , vol.44 , Issue.840 SUPPL.
    • Vignati, L.1    Brunelle, R.L.2
  • 33
    • 0000225411 scopus 로고
    • Lower within patient variability in postprandial glucose excursion with lispro insulin analog compared with regular insulin
    • Antsiferov M, Woodworth JR, Mayorov A, et al. Lower within patient variability in postprandial glucose excursion with lispro insulin analog compared with regular insulin [abstract]. Diabetes 1995; 44 Suppl. 777: 214A
    • (1995) Diabetes , vol.44 , Issue.777 SUPPL.
    • Antsiferov, M.1    Woodworth, J.R.2    Mayorov, A.3
  • 34
    • 9544243821 scopus 로고    scopus 로고
    • Effects of the short-acting insulin analog [Lys(B28). Pro(B29)] on postprandial blood glucose control in IDDM
    • Torlone E, Pampanelli S, Lalli C, et al. Effects of the short-acting insulin analog [Lys(B28). Pro(B29)] on postprandial blood glucose control in IDDM. Diabetes Care 1996; 19: 945-52
    • (1996) Diabetes Care , vol.19 , pp. 945-952
    • Torlone, E.1    Pampanelli, S.2    Lalli, C.3
  • 35
    • 0028864006 scopus 로고
    • Improved postprandial metabolic control after subcutaneous injection of a short-acting insulin analog in IDDM of short duration with residual pancreatic beta-cell function
    • Pampanelli S, Torlone E, Lalli C, et al. Improved postprandial metabolic control after subcutaneous injection of a short-acting insulin analog in IDDM of short duration with residual pancreatic beta-cell function. Diabetes Care 1995; 18: 1452-9
    • (1995) Diabetes Care , vol.18 , pp. 1452-1459
    • Pampanelli, S.1    Torlone, E.2    Lalli, C.3
  • 36
    • 0030042492 scopus 로고    scopus 로고
    • Pre-meal insulin analog insulin lispro vs. Humulin R insulin treatment in young subjects with type I diabetes
    • Garg SK, Carmain JA, Braddy KC, et al. Pre-meal insulin analog insulin lispro vs. Humulin R insulin treatment in young subjects with type I diabetes. Diabetic Med 1996; 13: 47-52
    • (1996) Diabetic Med , vol.13 , pp. 47-52
    • Garg, S.K.1    Carmain, J.A.2    Braddy, K.C.3
  • 37
    • 0030055378 scopus 로고    scopus 로고
    • Prandial glycemia after a carbohydrate-rich meal in type-I diabetic patients using the rapid acting insulin analog (Lyst B28), Pro(B29) human insulin
    • Heinemann L, Heise T, Wahl LC, et al. Prandial glycemia after a carbohydrate-rich meal in type-I diabetic patients using the rapid acting insulin analog (Lyst B28), Pro(B29) human insulin. Diabetic Med 1996; 13: 625-9
    • (1996) Diabetic Med , vol.13 , pp. 625-629
    • Heinemann, L.1    Heise, T.2    Wahl, L.C.3
  • 38
    • 0000000278 scopus 로고
    • Pharmacokinetics of a 'long-acting' human insulin analogue (HOE-901) in healthy subjects
    • Coates PA, Mukherjee S, Luzio S, et al. Pharmacokinetics of a 'long-acting' human insulin analogue (HOE-901) in healthy subjects [abstract]. Diabetes 1995; 44 Suppl. 478: 130A
    • (1995) Diabetes , vol.44 , Issue.478 SUPPL.
    • Coates, P.A.1    Mukherjee, S.2    Luzio, S.3
  • 39
    • 0024341392 scopus 로고
    • Impaired glucose tolerance in the U.S. population
    • Harris MI. Impaired glucose tolerance in the U.S. population. Diabetes Care 1989; 12: 464-74
    • (1989) Diabetes Care , vol.12 , pp. 464-474
    • Harris, M.I.1
  • 40
    • 0028261893 scopus 로고
    • Mechanisms of pancreatic B-cell dysfunction and glucose toxicity in non-insulin-dependent diabetes
    • Flatt PR, Barnett CR, Swanston-Flatt SK. Mechanisms of pancreatic B-cell dysfunction and glucose toxicity in non-insulin-dependent diabetes. Biochem Soc Trans 1994; 22 (1): 18-23
    • (1994) Biochem Soc Trans , vol.22 , Issue.1 , pp. 18-23
    • Flatt, P.R.1    Barnett, C.R.2    Swanston-Flatt, S.K.3
  • 42
    • 0040508837 scopus 로고
    • Hyattsville (MD): National Center for Health Statistics, (Stock #017-022-010-658)
    • National Center for Health Statistics. The national nursing home survey, 1985. Hyattsville (MD): National Center for Health Statistics, 1985: (Stock #017-022-010-658)
    • (1985) The National Nursing Home Survey, 1985
  • 43
    • 0026787025 scopus 로고
    • Use of premixed insulin among the elderly
    • Coscelli C, Calabrese G, Fedele D, et al. Use of premixed insulin among the elderly. Diabetes Care 1992; 15: 1628-30
    • (1992) Diabetes Care , vol.15 , pp. 1628-1630
    • Coscelli, C.1    Calabrese, G.2    Fedele, D.3
  • 44
    • 0028208703 scopus 로고
    • Intensive diabetes treatment: A new deal for older people
    • Kerr D, Haigh R. Intensive diabetes treatment: a new deal for older people [commentary]. Age Ageing 1994; 23: 89-90
    • (1994) Age Ageing , vol.23 , pp. 89-90
    • Kerr, D.1    Haigh, R.2
  • 45
    • 0025630035 scopus 로고
    • Insulin use in NIDDM
    • Genuth S. Insulin use in NIDDM. Diabetes Care 1990; 13: 1240-64
    • (1990) Diabetes Care , vol.13 , pp. 1240-1264
    • Genuth, S.1
  • 46
    • 0023916849 scopus 로고
    • Management of noninsulin dependent DM in Europe
    • Alberti KGMM, Gries FA. Management of noninsulin dependent DM in Europe. Diabet Med 1988; 5: 275-81
    • (1988) Diabet Med , vol.5 , pp. 275-281
    • Alberti, K.G.M.M.1    Gries, F.A.2
  • 47
    • 0028242619 scopus 로고
    • Insulin regimens for the non-insulin dependent: Impact on diurnal metabolic state and quality of life
    • Taylor R, Foster B, Kyne-Grzebalski D, et al. Insulin regimens for the non-insulin dependent: impact on diurnal metabolic state and quality of life. Diabet Med 1994; 11: 551-7
    • (1994) Diabet Med , vol.11 , pp. 551-557
    • Taylor, R.1    Foster, B.2    Kyne-Grzebalski, D.3
  • 48
    • 0025600988 scopus 로고
    • Treatment of NIDDM with insulin agonists or substitutes
    • Galloway JA. Treatment of NIDDM with insulin agonists or substitutes. Diabetes Care 1990; 13: 1209-39
    • (1990) Diabetes Care , vol.13 , pp. 1209-1239
    • Galloway, J.A.1
  • 49
    • 0021941892 scopus 로고
    • A practical guide to basal and prandial insulin therapy
    • Holman RR, Turner RC. A practical guide to basal and prandial insulin therapy. Diabet Med 1985; 2: 45-53
    • (1985) Diabet Med , vol.2 , pp. 45-53
    • Holman, R.R.1    Turner, R.C.2
  • 50
    • 0022549045 scopus 로고
    • The dawn phenomenon does not occur in normal elderly subjects
    • Meneilly GS, Elahi D, Minaker KL, et al. The dawn phenomenon does not occur in normal elderly subjects. J Clin Endocrinol Metab 1986; 63: 292-6
    • (1986) J Clin Endocrinol Metab , vol.63 , pp. 292-296
    • Meneilly, G.S.1    Elahi, D.2    Minaker, K.L.3
  • 51
    • 0027099874 scopus 로고
    • Morning or bed-time insulin with or without glibenclamide in elderly type 2 diabetic patients unresponsive to oral antidiabetic agents
    • Niskanen L, Lahti J, Uusitupa M. Morning or bed-time insulin with or without glibenclamide in elderly type 2 diabetic patients unresponsive to oral antidiabetic agents. Diabetes Res Clin Pract 1992; 18: 185-90
    • (1992) Diabetes Res Clin Pract , vol.18 , pp. 185-190
    • Niskanen, L.1    Lahti, J.2    Uusitupa, M.3
  • 52
    • 84941815781 scopus 로고
    • Insulin and a sulfonylurea agent in non-insulin dependent DM
    • Longnecker MP, Elsenhans VS, Leiman SM, et al. Insulin and a sulfonylurea agent in non-insulin dependent DM. Arch Intern Med 1986; 146: 673-6
    • (1986) Arch Intern Med , vol.146 , pp. 673-676
    • Longnecker, M.P.1    Elsenhans, V.S.2    Leiman, S.M.3
  • 53
    • 0022348508 scopus 로고
    • Treatment of poorly regulated non-insulin-dependent DM with combination insulin-sulfonylurea
    • Allen BT, Feinglos MN, Lebovitz HE. Treatment of poorly regulated non-insulin-dependent DM with combination insulin-sulfonylurea. Arch Intern Med 1985; 145: 1900-3
    • (1985) Arch Intern Med , vol.145 , pp. 1900-1903
    • Allen, B.T.1    Feinglos, M.N.2    Lebovitz, H.E.3
  • 54
    • 0027191312 scopus 로고
    • The combination of insulin and oral by poglycaemic drugs: A continuous challenge
    • Quatraro A, Giugliano D. The combination of insulin and oral by poglycaemic drugs: a continuous challenge. Diabete Metab 1993; 19: 219-24
    • (1993) Diabete Metab , vol.19 , pp. 219-224
    • Quatraro, A.1    Giugliano, D.2
  • 55
    • 0026049101 scopus 로고
    • The combined insulin and sulfonylurea therapy in diabetes of elderly people
    • Quatraro A, Consoli G, Minei A, et al. The combined insulin and sulfonylurea therapy in diabetes of elderly people. Arch Gerontol Geriatr 1991; 13: 245-54
    • (1991) Arch Gerontol Geriatr , vol.13 , pp. 245-254
    • Quatraro, A.1    Consoli, G.2    Minei, A.3
  • 56
    • 0021887834 scopus 로고
    • Combination of insulin and glibenclamide in the treatment of elderly non-insulin dependent (type II) diabetic patients
    • Kyllastynen M, Groop L. Combination of insulin and glibenclamide in the treatment of elderly non-insulin dependent (type II) diabetic patients. Ann Clin Res 1985; 17: 100-4
    • (1985) Ann Clin Res , vol.17 , pp. 100-104
    • Kyllastynen, M.1    Groop, L.2
  • 57
    • 0027746332 scopus 로고
    • Determinants of injecting insulin in elderly patients with type II DM
    • Wolffenbuttel BH, Drossaert CH, Visser AP. Determinants of injecting insulin in elderly patients with type II DM. Patient Educ Couns 1993; 22: 117-25
    • (1993) Patient Educ Couns , vol.22 , pp. 117-125
    • Wolffenbuttel, B.H.1    Drossaert, C.H.2    Visser, A.P.3
  • 58
    • 0025833955 scopus 로고
    • UKPDS VIII. Study design, progress and performance
    • UK Prospective Diabetes Study Group (UKPDS). UKPDS VIII. Study design, progress and performance. Diabetologia 1991; 34: 877-90
    • (1991) Diabetologia , vol.34 , pp. 877-890
  • 59
    • 0028963260 scopus 로고
    • UKPDS (UKPDS) 13: Relative efficacy of randomly allocated diet, sulphonylurea, insulin or metformin in patients with newly diagnosed non-insulin dependent diabetes followed tor 3 years
    • UK Prospective Diabetes Study Group. UKPDS (UKPDS) 13: relative efficacy of randomly allocated diet, sulphonylurea, insulin or metformin in patients with newly diagnosed non-insulin dependent diabetes followed tor 3 years. BMJ 1995; 31: 83-8
    • (1995) BMJ , vol.31 , pp. 83-88
  • 60
    • 0028817815 scopus 로고
    • UK prospective diabetes study 16: Overview of 6 years of therapy of type II diabetes: A progressive disease
    • UK Prospective Diabetes Study Group. UK prospective diabetes study 16: overview of 6 years of therapy of type II diabetes: a progressive disease. Diabetes 1995; 44: 1249-58
    • (1995) Diabetes , vol.44 , pp. 1249-1258
  • 61
    • 0026787025 scopus 로고
    • Use of premixed insulin among the elderly: Reduction of errors in patient preparation of mixtures
    • Zappella A. Use of premixed insulin among the elderly: reduction of errors in patient preparation of mixtures. Diabetes Care 1992; 15: 1628-30
    • (1992) Diabetes Care , vol.15 , pp. 1628-1630
    • Zappella, A.1
  • 62
    • 0028360676 scopus 로고
    • Use of premixed insulin regimen (Novolin 70/30) to replace self-mixed insulin regimens
    • Aronoff S, Golderber R, Kumar D, et al. Use of premixed insulin regimen (Novolin 70/30) to replace self-mixed insulin regimens. Clin Ther 1994; 16: 41-9
    • (1994) Clin Ther , vol.16 , pp. 41-49
    • Aronoff, S.1    Golderber, R.2    Kumar, D.3
  • 63
    • 0025954852 scopus 로고
    • Type II diabetic subjects with secondary failure: Treatment with prebreakfast mixed ultralente and regular insulin with a sulfonylurea
    • Kabadi UM, Kabadi M. Type II diabetic subjects with secondary failure: treatment with prebreakfast mixed ultralente and regular insulin with a sulfonylurea. J Fam Pract 1991; 33: 349-53
    • (1991) J Fam Pract , vol.33 , pp. 349-353
    • Kabadi, U.M.1    Kabadi, M.2
  • 64
    • 0025796848 scopus 로고
    • Premixed insulin at ratio 3/7 and regular + isophane insulins at mixing ratios from 2/8 to 4/6 achieve the same metabolic control
    • Cucinotta D, Mannino D, Lasco A, et al. Premixed insulin at ratio 3/7 and regular + isophane insulins at mixing ratios from 2/8 to 4/6 achieve the same metabolic control. Diabete Metab 1991; 17: 49-54
    • (1991) Diabete Metab , vol.17 , pp. 49-54
    • Cucinotta, D.1    Mannino, D.2    Lasco, A.3
  • 65
    • 0019428637 scopus 로고
    • Treatment of a type II diabetic by a totally implantable insulin infusion device
    • Buchwald H, Barbosa J, Varco RL, et al. Treatment of a type II diabetic by a totally implantable insulin infusion device. Lancet 1981; 1: 1233-4
    • (1981) Lancet , vol.1 , pp. 1233-1234
    • Buchwald, H.1    Barbosa, J.2    Varco, R.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.