Pathogenesis and pathology of liver disease associated with α1- antitrypsin deficiency

Chest

Volumn 110, Issue 6 SUPPL., 1996, Pages 251S-255S

  Massi, Guido ^a  

^a CATHOLIC UNIVERSITY   (Italy)

Author keywords

cholestasis; liver disease; lung disease; 1 antitrypsin deficiency

Indexed keywords

ALPHA 1 ANTITRYPSIN DEFICIENCY; CHRONIC OBSTRUCTIVE LUNG DISEASE; DISEASE ASSOCIATION; HUMAN; INFANT DISEASE; LIVER DISEASE; MOLECULAR BIOLOGY; PATHOGENESIS; PRIORITY JOURNAL; REVIEW;

EID: 0030478167     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.110.6_Supplement.251S     Document Type: Article

References (51)

1. Sharp HL, Bridges RA, Krivit W, et al. Cirrhosis associated with alpha-1-antitrypsin deficiency, a previously unrecognized disorder. J Lab Clin Med 1968; 73:934-39
2. Lomas DA, Finch JT, Seyama K, et al. Alpha-1-antitrypsin Siiyama (Ser 53→Phe). J Biol Chem 1993; 93:15333-35
3. Cox DW, Smith SH. Risk for liver disease in adults with alpha-1-antitrypsin deficiency. Am J Med 1983; 74:221-27
4. Crowley JJ, Sharp HL, Freier E, et al. Fatal liver disease associated with alpha-1-antitrypsin deficiency PiM1 PiMduarte. Gastroenterology 1987; 93:342-44
5. Curiel DT, Holmes MD, Okayama H, et al. Molecular basis of the liver and lung disease associated with the alpha-1-antitrypsin deficiency allele Mmalton. J Biol Chem 1989; 264:13938-45
6. Lomas DA, Evans DLI, Finch JT, et al. The mechanism of Z alpha-1-antitrypsin accumulation in the liver. Nature 1992; 357:605-07
7. Lomas DA, Carrell RW. A protein structural approach to the solution of biological problems: alpha 1-antitrypsin as a recent example. Am Physiol 1993; 265:L211-19
8. Brantly M, Toshihoro N, Crystal RG. Molecular basis of alpha-1-antitrypsin deficiency. Am J Med 1988; 84:13-31
9. Sifers RN, Finegold MJ, Woo SLC. Molecular biology and genetics of alpha-1-antitrypsin deficiency. Semin Liver Dis 1992; 12:301-10
10. Birrer P, Mc Elvaney NG, Chang-Stroman LM, et al. Alpha-1-antitrypsin deficiency and liver disease. J Inherited Metab Dis 1991; 14:512-25
11. Eriksson SG. Liver disease in alpha-1-antitrypsin deficiency. Scand J Gastroenterol 1985; 20:907-11
12. Feldman G. Foie er deficit hereditaire en alpha-1-antitrypsine. Gastroenterol Clin Biol 1993; 17:83-93
13. Mowat AP. Liver disorders in childhood. London: Butterworths, 1987; 37-53
14. Mowat AP. Alpha-1-antitrypsin deficiency (PiZZ): features of liver involvement in childhood. Acta Paediatr 1994; 393(suppl):13-7
15. Nemeth A. Pathogenesis of liver disease in alpha-1-antitrypsin deficiency. Acta Paediatr 1994; 393(suppl):5-7
16. Vogel W, Propst T, Propst A, et al. Causes of liver disease in an adult population with heterozygous and homozygous alpha-1-antitrypsin deficiency. Acta Paediatr 1994; 393(suppl):24-6
17. Mondelli M, Mieli-Vergani G, Eddleston ALWF, et al. Lymphocyte cytotoxicity to autologous hepatocytes in alpha-1-antitrypsin deficiency. Gut 1984; 25:1044-49
18. Revillard JP, Cordier G, Bata J, et al. Modulation of human lymphocyte responses by alpha-1-antitrypsin and alpha-2-macroglobulin. In: Amaud P, Bienvenu J, Lauren P, eds. Marker proteins in inflammation (vol 2). Berlin: Walter de Gruyter, 1984; 207-17
19. Littleton ET, Bevis L, Hansen LJ, et al. Alpha-1-antitrypsin deficiency, complement activation, and chronic liver disease. J Clin Pathol 1991; 44:855-58
20. Ruoslahti E, Pierschbacher MD. Molecular basis of cell-extracellular matrix interactions In: Arias IM, Jakoby WP, Popper H, eds. The liver biology and pathobiology. 2nd ed. New York: Raven Press, 1987; 739-45
21. Mavier P, Preaux A-M, Guigul B, et al. In vitro toxicity of polymorphonuclear neutrophils to hepatocytes: evidence for a proteinase-mediated mechanism. Hepatology 1988; 8:254-56
22. Weiss SJ. Tissue destruction by neutrophils. N Engl J Med 1989; 320:365-76
23. Pittschieler K. Heterozygotes and liver involvement. Acta Paediatr 1994; 393(suppl):21-3
24. Pittschieler K, Massi G. Liver involvement in infants with PiSZ phenotype of alpha 1-antitrypsin deficiency. J Pediatr Gastroenterol Nutr 1992; 15:315-18
25. Nemeth A, Strandvik B. Natural history of children with alpha-1-antitrypsin deficiency and neonatal cholestasis. Acta Paediatr Scand 1982; 71:993-99
26. Perlmutter DH, Schlesinger MJ, Pierce JA, et al. Synthesis of stress proteins is increased in individuals with PiZZ alpha-1-antitrypsin deficiency and liver disease. J Clin Invest 1989; 85:1551-61
27. Schwarzenber SJ, Sharp HL. Pathogenesis of alpha-1-antitrypsin deficiency-associated liver disease, 1990. J Pediatr Gastroenterol Nutr 1990; 10:5-12
28. De Medina M, Li X, Schiff ER. The liver disease in children associated with alpha-1-antitrypsin deficiency is not related to hepatitis C virus. Hepatology 1992; 16:230A
29. Ghishan FK, Gray GF, Green HL, Alpha 1-antitrypsin deficiency presenting with ascites and cirrhosis in the neonatal period. Gastroenterology 1983; 85:435-39
30. Malone M, Mieli-Vergani G, Mowat AP, et al. The fetal liver in PiZZ alpha-1-antitrypsin deficiency: a report of five cases. Pediatr Pathol 1989; 9:623-31
31. Sveger T. Screening for alpha-1-antitrypsin deficiency. Acta Paediatr 1994; 393(suppl):18-20
32. Sveger T. The natural history of liver disease in alpha-1-antitrypsin deficient children. Acta Paediatr Scand 1988; 77: 847-51
33. Burdelski M. Diagnostic, preventive, medical and surgical management of alpha-1-antitrypsin deficiency in childhood. Acta Paediatr 1994; 393(suppl):33-6
34. Sharp HL, Mathis R, Krivit W, et al. The liver in non-cirrhotic alpha-1-antitrypsin deficiency. J Lab Clin Med 1971; 78:1012-13
35. Steenberg W. Alpha-1-antitrypsin deficiency: an overview. Acta Clin Belg 1993; 48:171-83
36. Hussain M, Mieli-Vergani G, Mowat AP. Alpha-1-antitrypsin deficiency and liver disease: clinical presentation, diagnosis and treatment. J Inherit Metab Dis 1991; 14:497-511
37. Hadchouel M, Gautier M. Histopathologic study of the liver in the early cholestatic phase of alpha 1 antitrypsin deficiency. J Pediatr 1976; 89:211-16
38. Odievre M, Martin JP, Hadchouel M, et al. Alpha 1 antitrypsin liver disease in children: phenotypes, manifestations and prognosis. Pediatrics 1976; 57:226-31
39. Deutsch J, Becker H, Aubock L. Histopathological features of liver disease in alpha-1-antitrypsin deficiency. Acta Paediatr 1994; 393(suppl):8-12
40. Brantly ML, Paul LD, Miller BH, et al. Clinical features and history of the destructive lung disease associated with alpha-1-antitrypsin deficiency of adults with pulmonary symptoms. Am Rev Respir Dis 1988; 138:327-36
41. Cox DW. Alpha-1-antitrypsin deficiency. In: Scriver CR, Beaudet AL, Sly WS, eds. The metabolic basis of inherited disease. New York: McGraw-Hill, 1989; 2409-37
42. Crystal RG. Alpha 1 antitrypsin deficiency, emphysema and liver disease: genetic basis and strategy for therapy. J Clin Invest 1990; 85:1343-52
43. Eriksson S, Carlson S, Velez R. Risk of cirrhosis and primary liver cancer in alpha-1-antitrypsin deficiency. N Engl J Med 1986; 314:735-39
44. Eriksson S, Hagerstrand I. Cirrhosis and malignant hepatoma in alpha-1-antitrypsin deficiency. Acta Med Scand 1974; 195:451-58
45. Triger DR, Millward-Sadler GH, Czaykowski AA, et al. Alpha-1-antitrypsin deficiency and liver disease in adults. Q J Med 1976; 45:351-72
46. Carlson J Eriksson S. Chronic cryptogenic liver disease and malignant hepatoma in intermediate alpha-1-antitrypsin deficiency identified by a Pi-Z specific monoclonal antibody. Scand J Gastroenterol 1985; 20:835-42
47. Eriksson S, Moestrup T, Hagerstrand I. Liver, lung and malignant disease in heterozygous Pi MZ alpha-1-antitrypsin deficiency. Acta Med Scand 1975; 198:243-47
48. Poley JR. Malignant liver disease in alpha-1-antitrypsin deficiency. Acta Paediatr 1994; 393(suppl):27-32
49. Parham DM, Peterson JR, Gunn A, et al. Cholangiocarcinoma in two siblings with emphysema and alpha-1-antitrypsin deficiency. Q J Med 1989; 71:359-67
50. Quizilbash A, Young-Pong O. Alpha-1-antitrypsin liver disease: differential diagnosis of PAS-positive, diastase-resistant globules in liver cells. Am J Clin Pathol 1983; 79:697-702
51. Starzl TE, Porter KA, Francavilla A, et al. Reversal of hepatic alpha-1-antitrypsin deposition after portocavol shunt. Lancet 1983; 2:424-26