Lessons from combination therapy in veterans affairs studies

American Journal of Hypertension

Volumn 9, Issue 12 SUPPL. 1, 1996, Pages S187-S191

  Materson, Barry J ^a   Reda, Domenic J ^b   Williams, David ^b  

^a UNIVERSITY OF MIAMI   (United States)

^b NONE

Author keywords

Antihypertensive therapy; Atenolol; Captopril; Clonidine; Combination therapy; Diltiazem; Hydrochlorothiazide; Hypertension; Prazosin

Indexed keywords

ATENOLOL; CAPTOPRIL; CLONIDINE; DILTIAZEM; HYDROCHLOROTHIAZIDE; PRAZOSIN;

AGE; ARTICLE; DIASTOLIC BLOOD PRESSURE; DRUG EFFICACY; DRUG RESPONSE; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RACE;

ANTIHYPERTENSIVE AGENTS; DRUG THERAPY, COMBINATION; HUMANS; HYPERTENSION; MIDDLE AGED; TREATMENT OUTCOME; VETERANS;

EID: 0030477921     PISSN: 08957061     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0895-7061(96)00389-5     Document Type: Article

References (8)

1. Veterans Administration Cooperative Study on Anti-hypertensive Agents: Effects of treatment on morbidity in hypertension. Results in patients with diastolic blood pressures averaging 115 through 129 mm Hg. JAMA 1967;202:1028-1034.
2. Veterans Administration Cooperative Study on Anti-hypertensive Agents: Efficacy of nadolol alone and combined with bendroflumethiazide and hydralazine for hypertension. Am J Cardiol 1983;52:1230-1237.
3. Veterans Administration Cooperative Study on Anti-hypertensive Agents: Low-dose captopril for the treatment of mild to moderate hypertension. I. Results of a 14-week trial. Arch Intern Med 1984;144:1947-1953.
4. Participating Veterans Administration Medical Centers: Low doses vs. standard dose of reserpine. A randomized, double-blind, multiclinic trial in patients taking chlorthalidone. JAMA 1982;248:2471-2477.
5. Veterans Administration Cooperative Study on Anti-hypertensive Agents: Propranolol in the treatment of essential hypertension. JAMA 1977;237:2303-2310.
6. Materson BJ, Reda DJ, Cushman WC, et al: Single-drug therapy for hypertension in men; a comparison of six antihypertensive agents with placebo. N Engl J Med 1993;328:914-921.
7. Materson BJ, Reda DJ, Cushman WC, Henderson WG, for the Department of Veterans Affairs Cooperative Study Group on Anti-hypertensive Agents: Results of combination of anti-hypertensive therapy after failure of each of the components. J Human Hypertens 1995; 9:791-796.
8. Materson BJ, Reda DJ, Preston RA, et al: Response to a second single antihypertensive agent used as monotherapy for hypertension after failure of the initial drug. Arch Intern Med 1995;155:1757-1762.