Alanine scan and TV-methyl amide derivatives of Ac-bombesin[7-14] Development of a proposed binding conformation at the neuromedin B (NMB) and gastrin releasing peptide (GRP) receptors

International Journal of Peptide and Protein Research

Volumn 48, Issue 6, 1996, Pages 522-531

  Horwell, David C ^a   Howson, William ^a   Naylor, Dorica ^a   Osborne, Simon ^a   Pinnock, Robert D ^a   Ratcliffe, Giles S ^a   Suman Chauhan, Nirmala ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

A' methylation scan; Alanine scan; Bombesin; GRP; Hydrogen bonds; Molecular modelling; NMB; Proposed binding conformation

Indexed keywords

BOMBESIN DERIVATIVE; NEUROPEPTIDE RECEPTOR;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG RECEPTOR BINDING; GENE EXPRESSION; HUMAN; MOLECULAR DYNAMICS; MOLECULAR MODEL; NONHUMAN; PEPTIDE SYNTHESIS; PROTEIN STRUCTURE; QUANTUM CHEMISTRY;

AMIDES; AMYLASES; ANIMALS; BOMBESIN; CHO CELLS; CRICETINAE; HUMANS; HYDROGEN BONDING; METHYLATION; MODELS, MOLECULAR; PEPTIDE FRAGMENTS; PEPTIDES, CYCLIC; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, BOMBESIN; SOFTWARE;

ANIMALIA;

EID: 0030477855     PISSN: 03678377     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-3011.1996.tb00871.x     Document Type: Article

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