Unexpected HLA haplotype sharing in dizygotic twin pairs discordant for rheumatoid arthritis

Journal of Medical Genetics

Volumn 33, Issue 12, 1996, Pages 1015-1018

  Jawaheer, Damini ^a,b   MacGregor, Alexander J ^a   Gregersen, Peter K ^b   Silman, Alan J ^a   Ollier, William E R ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b NORTH SHORE UNIVERSITY HOSPITAL   (United States)

Author keywords

Dizygotic twins; HLA; Twin studies

Indexed keywords

HLA A ANTIGEN; HLA B ANTIGEN; HLA C ANTIGEN; HLA DR ANTIGEN;

ARTICLE; CONTROLLED STUDY; DIZYGOTIC TWINS; FEMALE; HAPLOTYPE; HLA SYSTEM; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SIBLING; TWIN DISCORDANCE;

EID: 0030477540     PISSN: 00222593     EISSN: None     Source Type: Journal    
DOI: 10.1136/jmg.33.12.1015     Document Type: Article

References (12)

1. Gregersen PK. Discordance for autoimmunity in monozygotic twins. Are identical twins really identical? Arthritis Rheum 1993;36:1185-92.
2. Hay EM, Ollier WER, Silman AJ. The Arthritis and Rheumatism Council's National Family Material Repository. Br J Rheumatol 1993;32:443-4.
3. MacGregor AJ, Bamber S, Silman AJ. A comparison of the performance of different methods of disease classification for rheumatoid arthritis. Results from the analysis from a nationwide twin study. J Rheumatol 1994;21:1420-6.
4. Silman AJ, MacGregor AJ, Thomson W, et al. Twin concordance rates for rheumatoid arthritis: results from a nationwide study. Br J Rheumatol 1993;32:903-7.
5. Thomson W, Ollier WER. Non-radioactive ASO typing for class II: the way forward. Eur J Immunogenet 1992;19:169-75.
6. Staub Nielsen L, Eiberg H, Fenger K, Mohr J. An MHC (HLA-A, -B, C2, BF, HLA-DR, GLO1) haplotype study of 497 Danish normal families with 1970 children including 97 twin pairs. Tissue Antigens 1990;36:141-8.
7. H2 phenomenon? Immunol Today 1993;14:353-6.
8. Laitinen T, Koskimies S, Westman P. Foeto-maternal compatibility in HLA-DR, -DQ and -DP loci in Finnish couples suffering from recurrent spontaneous abortions. Eur J Immunogenet 1993;20:249-58.
9. Ober C, Elias S, Kostyu DD, Hauck WW. Decreased fecundability in Hutterite couples sharing HLA-DR. Am J Hum Genet 1992;50:6-14.
10. Nelson JL, Hughes KA, Smith AG, Nisperos BE, Branchaud AM, Hansen JA. Maternal-fetal disparity in HLA class II alloantigens and the pregnancy-induced amelioration of rheumatoid arthritis. N Engl J Med 1993;329:500-1.
11. Landy HJ, Keith L, Keith D. The vanishing twin. Acta Genet Med Gemellol (Roma) 1982;31:179-94.
12. Radvany RM, Vaisrub N, Ober C, Patel KM, Hecht F. The human sex ratio: increase in first-born males to parents with shared HLA-DR antigens. Tissue Antigens 1987;29:34-12.