Cellular immediate-early genes and cell death in the nervous system

Neuropathology and Applied Neurobiology

Volumn 22, Issue 6, 1996, Pages 484-488

  Herzog, K H ^a   Morgan, J I ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

AP 1; c fos; c jun; Growth factors; Knockout mice; Programmed cell death

Indexed keywords

APOPTOSIS; CELL DEATH; CONFERENCE PAPER; IMMEDIATE EARLY GENE; NERVE CELL NECROSIS; ONCOGENE C FOS; ONCOGENE C JUN; PRIORITY JOURNAL;

EID: 0030477535     PISSN: 03051846     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2990.1996.tb01120.x     Document Type: Conference Paper

References (26)

1. Anderson AJ, Pike CJ, Colman CW. Differential induction of immediate early gene proteins in cultured neurons by β-amyloid (Aβ): association of c-Jun with Aβ-induced apoptosis. J Neurochem 1995; 65: 1487-98
2. Barbacid M. The Trk family of neurotrophin receptors. J Neurobiol 1994; 25: 1386-403
3. Beato M, Herrlich P, Schütz G. Steroid hormone receptors: many actors in search of a plot. Cell 1995; 83: 851-7
4. Bossy-Wetzel E, Bravo R, Hanahan D. Transcription factors JunB and c-Jun are selectively up-regulated and functionally implicated in fibrosarcoma development. Genes Dev 1992; 6: 2340-51
5. Buttyan R, Zakeri Z, Lockshin R, Wolgemuth D. Cascade induction of c-fos, c-myc, and heat shock 70K transcripts during regression of the rat ventral prostate gland. Mol Endocrinol 1988; 2: 650-7
6. Colotta F, Polentarutti N, Sironi M, Mantovani A. Expression and involvement of c-fos and C-jun protooncogenes in programmed cell death induced by growth factor deprivation in lymphoid cell lines. J Biol Chem 1992; 267: 18278-83
7. Davis RJ. MAPKs: new JNK expands the group. Trends Biochem Sci 1994; 19: 470-3
8. Estus S, Zaks WJ, Freeman RS, Gruda M, Bravo R, Johnson EM Jr. Altered gene expression in neurons during programmed cell death: Identification of c-jun as necessary for neuronal apoptosis. J Cell Biol 1994; 127: 1717-27
9. Ferrer I, Olivé M, Blanco R, Cinós C, Planas AM. Selective c-Jun overexpression is asscociated with ionizing radiation-induced apoptosis in the developing cerebellum of the rat. Mol Brain Res 1996; 38: 91-100
10. Gupta S, Campbell P, Dérijard B, Pavis RJ. Transcription factor ATF2 regulation by the JNK signal transduction pathway. Sience 1995; 267: 389-93
11. Haas CA, Deller T, Naumann T, Frotscher M. Selective expression of the immediate early gene c-jun in axotomized rat medial septal neurons is not related to neuronal degeneration. J Neurosci 1996; 16: 1894-903
12. Ham J, Babij C, Whitfield J, Pfarr CM, Lallemand D, Yaniv M, Rubin LL. A c-jun dominant negative mutant protects sympathetic neurons against programmed cell death. Neuron 1995; 14: 927-39
13. Jenkins R, Hunt SP. Long-term increase in the levels of c-jun mRNA and jun protein-like immunoreactivity in motor and sensory neurons following axon damage. Neurosci Lett 1991; 129: 107-10
14. Kasof GM, Mandelzys A, Maika SD, Hammer RF, Curran T, Morgan JI. Kainic acid-induced neuronal death is associated with DNA damage and a unique immediate-early gene response in c-fos-lacZ transgenic rats. J. Neurosci 1995; 15: 4238-49
15. Martin DP, Schmidt RE, DiStefano PS, Lowry OH, Carter JG, Johnson EM Jr. Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation. J Cell Biol 1988; 106: 829-44
16. Morgan JI, Curran T. Stimulus-transcription coupling in the nervous system: involvement of the inducible protooncogenes fos and jun. Annu Rev Neurosci 1991; 14: 421-51
17. Morgan JI, Curran T. The immediate-early gene response and neuronal death and regeneration. The Neuroscientist 1995; 1: 68-75
18. Oltvai ZN, Millman CL, Korsmeyer SJ. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 1993; 74: 609-19
19. Purves D. Body and Brain. A Trophic Theory of Neurol Connections. Cambridge. MA: Harvard University Press, 1988
20. Raghupathi R, McIntosh TK. Regionally and temporally distinct patterns of induction of c-fos, c-jun and junB mRNAs following experimental brain injury in the rat. Mol Brain Res. 1996; 37: 134-44
21. Reimold AM, Grusby MJ, Kosaras B et al. Chondrodysplasia and neurological abnormalities in ATF-2-deficient mice. Nature 1996; 379: 262-5
22. Roffler-Tarlov S, Brown JJG. Tarlov E et al. Programmed cell death in the absence of c-Fos and c-Jun. Development 1996; 122: 1-9
23. Soares HD, Chen S-C, Curran T, Morgan JI. The induction of C-jun and c-fos following sciatic nerve transection. Soc Neurosci Abs 1994; 20
24. Smeyne RJ, Vendrell M, Hayward M et al. Continuous c-fos expression precedes programmed cell death in vivo. Nature 1993; 363: 166-9
25. Wisdom R, Verma IM. Proto-oncogene FosB: the amino terminus encodes a regulatory function required for transformation. Mol Cell Biol 1993; 13: 2635-43
26. Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 1995; 270: 1326-31