Does ibuprofen affect bilirubin-albumin binding in newborn infant serum?

Pharmacology and Toxicology

Volumn 79, Issue 6, 1996, Pages 297-299

  Cooper Peel, Celeste ^b   Brodersen, Rolf ^b   Robertson, Alex ^a  

^a EAST CAROLINA UNIVERSITY   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; BILIRUBIN; IBUPROFEN;

ADULT; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; KERNICTERUS; NEWBORN; PREMATURITY; PRIORITY JOURNAL; SERUM;

EID: 0030477228     PISSN: 09019928     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0773.1996.tb00012.x     Document Type: Article

References (10)

1. Aranda, J. V., N. Varvarigou, K. Beharry, H. Modanlou, I. Bottolli, C. Bardin & A. Papageorgiou: Pharmacokinetics of intravenous [IV] ibuprofen in premature newborns. Pediatric Res. 1994, 35, 81A.
2. Brodersen, R. & A. Rohertson: Chemistry of bilirubin and its interaction with albumin. In: Eds.: R. L. Levine, M. J. Maisels, Hyperbilirubinemia in the newborn. Report of the Eighty-Fifth Ross Conference on Pediatric Research, Ross Laboratories, Columbus, Ohio, 1983, pp. 91-101.
3. Brodersen, R., C. Jacobsen, H. Iversen & F. Lundquist: The chemical nature of fetal albumin. In: Neonatal jaundice. New trends in phototherapy. Eds.: F. F. Rubaltelli and G. Jori. Plenum Press, New York, 1984, pp. 51-54.
4. Brodersen, R., H. Vorum & A. Robertson: Displacement of one ligand by another calculated from the reverse displacement of the second ligand by the first. J. Pharm. Sci. 1995, 84, 148-151.
5. Harris, R.C., J.F. Lucey & J.R. MacLean: Kernicterus in premature infants associated with low concentrations of bilirubin in the plasma. Pediatrics 1958, 21, 875-883.
6. Honoré, B. & R. Brodersen: Albumin binding of anti-inflammatory drugs: utility of a site-oriented vs. a stoichiometric analysis. Mol. Pharmacol. 1984, 25, 137-150.
7. Ivarson, P.R. & R. Brodersen: Displacement of bilirubin by a drug and fatty acid on binding to adult and newborn serum albumin. Develop. Pharmacol. Therap. 1989, 12, 19-29.
8. Robertson, A. & R. Brodersen: The effect of lactate, pyruvate, acetone, acetoacetate and β-hydroxybutyrate on albumin binding of bilirubin. J. Pediatr. 1983, 102, 433-438.
9. Robertson, A., W. Karp & R. Brodersen: Bilirubin displacing effect of drugs used in neonatology. Acta Pediatr. Scand. 1991, 80, 1119-1127.
10. Varvarigou, A., C. L. Bardin, K. Beharry, S. Chemtob, A. Papageorgiou & J. V. Aranda: Early ibuprofen administration to prevent patent ductus arteriosus in premature newborn infants. JAMA 1996, 275, 539-544.