Simultaneous determination of dextromethorphan and dextrorphan in human plasma, urine and cerebrospinal fluid by HPLC with fluorescence detection

Journal of Liquid Chromatography and Related Technologies

Volumn 19, Issue 8, 1996, Pages 1267-1275

  Kimiskidis, V K ^a   Kazis, A D ^a   Niopas, I ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITUSSIVE AGENT; DEXTROMETHORPHAN; DEXTRORPHAN; DRUG METABOLITE; LEVALLORPHAN;

ACCURACY; ARTICLE; CALIBRATION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CEREBROSPINAL FLUID LEVEL; DRUG DETERMINATION; DRUG MIXTURE; DRUG URINE LEVEL; EPILEPSY; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; LIQUID LIQUID EXTRACTION; ORAL DRUG ADMINISTRATION; TECHNIQUE;

EID: 0030476907     PISSN: 10826076     EISSN: None     Source Type: Journal    
DOI: 10.1080/10826079608006317     Document Type: Article

References (18)

1. J. R. Woodworth, S. R. K. Dennis, O. N. Hinsvark, L. P. Amsel, K. S. Rotenberg, J. Clin. Pharmacol., 27, 133-138 (1987).
2. H. Char, S. Kumar, S. Patel, D. Piemontese, K. Iqbal, A. Waseem, R. A. Salvador, C. R. Behl, J. Pharm. Sci., 81, 750-753 (1992).
3. D. W. Choi, Brain Res., 403, 333-336 (1988).
4. F. C. Tortella, M. Pellicano, N. G. Bowery, Trends Pharmacol. Sci., 10, 501-507 (1989).
5. B. Schmid, R. Bircher, A. Kupfer, Clin. Pharmacol. Ther., 38, 618-624 (1985).
6. A. Kupfer, B. Schmid, R. Preisig, G. Pfaff, Lancet, 2, 517-518 (1984).
7. K. Broseru Clin. Pharmacokinet., 18, 220-239 (1990).
8. U. A. Meyer, Clin. Pharmacol., 4, 595-615 (1990).
9. E. Jacqz, H. Dulac, H. Mathieu, Eur. J. Clin. Pharmacol., 35, 167-171 (1986).
10. R. J. Guttendorf, M. Britto, R. A. Blouin, T. S. Foster, W. John, K. A. Pittman, P. J. Wedlund, Br. J. Clin. Pharmacol., 29, 373-380 (1990).
11. Y. H. Par, M. P. Kullberg, O.N. Hinsvark, J. Pharm. Sci., 73, 24-29 (1984).
12. T. East, D. Dye, J. Chromatogr., 338, 99-112 (1985).
13. O. Mortimer, B. Lindstrom, H. Laurell, A. Rane, U. Bergman, Br. J. Clin. Pharmacol., 27, 223-227 (1989).
14. Z. R. Chen, A. A. Somogyi, F. Bochner, Ther. Drug Monit., 12, 97-104 (1990).
15. S. Jaruratanasirikul, A. D. Cooper and T. F. Blaschke, Drug Metab. Disp., 20, 379-382 (1992).
16. P. S. Marshall, R. J. Straka, K. Johnson K, Ther. Drug Monit., 14, 402-407 (1992).
17. Y. W. F. Lam, S. Y. Rodriguez, Ther. Drug Monit., 15, 300-304 (1993).
18. A. D. Kazis, V. K. Kimiskidis, I. Niopas, Acta Neurol. Scand., in press (1996).