The effects of in vivo and in vitro non-enzymatic glycosylation and glycoxidation on physico-chemical properties of haemoglobin in control and diabetic patients

International Journal of Biochemistry and Cell Biology

Volumn 28, Issue 12, 1996, Pages 1393-1403

  Watala, Cezary ^a   Golański, Jacek ^a   Witas, Henryk ^a   Gurbiel, Ryszard ^b   Gwoździński, Krzysztof ^c   Trojanowski, Zygmunt ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

^b JAGIELLONIAN UNIVERSITY   (Poland)

^c UNIVERSITY OF LODZ   (Poland)

Author keywords

Diabetes mellitus; Erythrocyte deformability; Erythrocyte internal viscosity; ESR; Glycated haemoglobin; Glycoxidation; Non enzymatic glycosylation

Indexed keywords

ANTIDIABETIC AGENT; HEMOGLOBIN; HEMOGLOBIN A1C; INSULIN;

ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; ELECTRON SPIN RESONANCE; ERYTHROCYTE; ERYTHROCYTE DEFORMABILITY; FEMALE; GLYCOSYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OXIDATION; PROTEIN MODIFICATION; SPIN LABELING; VISCOSITY;

ADULT; AGED; CASE-CONTROL STUDIES; CHEMISTRY, PHYSICAL; DIABETES MELLITUS, TYPE 2; ELECTRON SPIN RESONANCE SPECTROSCOPY; ERYTHROCYTE DEFORMABILITY; FEMALE; GLYCOSYLATION; HEMOGLOBIN A, GLYCOSYLATED; HEMOGLOBINS; HUMANS; MALE; MIDDLE AGED; MOLECULAR STRUCTURE;

EID: 0030476805     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1357-2725(96)00087-8     Document Type: Article

References (40)

1. Abraham E. C. and Elseweidy M. M. (1986) Nonenzymatic glycosylation influences Hb S polymerization. Hemoglobin 10, 173-183.
2. Aster R. H. and Jandl J. H. (1964) Platelet sequestration in man. I. Methods. J. Clin. Invest. 43, 843-855.
3. Brownlee M., Vlassara H. and Cerami A. (1984) Nonenzymatic glycosylation and the pathogenesis of diabetic complications. Ann. Int. Med. 101, 527-537.
4. Brownlee M. and Cerami A. (1981) The biochemistry of the complications of diabetes mellitus. Annu. Rev. Biochem. 50, 385-432.
5. Bryszewska M. (1988) Interaction of normal and glycated haemoglobin with erythrocyte membranes from normal and diabetic individuals. J. Clin. Chem. Clin. Biochem. 26, 809-813.
6. Cecchin E., De Marchi S., Panarello G. and De Angelis V. (1987) Rheological abnormalities of erythrocyte deformability and increased glycosylation of hemoglobin in the nephrotic syndrome. Am. J. Nephrol. 7, 18-21.
7. Chasis J. A. and Shohet S. B. (1987) Red blood cell biochemical anatomy and membrane properties. Annu. Rev. Physiol. 49, 237-248.
8. Chien S., Kaperonis A. A., King R, G.. Lipkowsky H. H., Schmalzer E. A., Sung L. A. and Usami S. (1987) Rheology of sickle cells and its role in microcirculatory dynamics. Prog. Clin. Biol. Res. 240, 151-165.
9. Clark M. R. (1989) Mean corpuscular hemoglobin concentration and cell deformability. Ann. N.Y. Acad. Sci. 565, 284-294.
10. Drabkin D. L. (1946) Spectrophotometric studies. XIV. The crystallographic and optical properties of the hemoglobin of man in comparison with those of other species. J. biol. Chem. 164, 703-723.
11. Hebbel R. P. (1991) Beyond hemoglobin polymerization: the red blood cell membrane and sickle disease pathophysiology. Blood 77, 214-237.
12. Herrmann A. and Muller P. (1986) Correlation of the internal viscosity of human erythrocytes to the cell volume and the viscosity of haemoglobin solutions. Biochim. Biophys. Acta 885, 80-87.
13. Hochmuth R. M. and Waugh R. E. (1987) Erythrocyte membrane elasticity and viscosity. Annu. Rev. Physiol. 49, 209-219.
14. Judkiewicz L., Ciszewski R. and Bartosz G. (1987) Susceptibility of erythrocytes to centrifugal packing. I. Survey of healthy population and of diabetic patients. Clin. Hemorrheol. 7, 321-329.
15. Keith A., Bulfield G. and Snipes W. (1970) Spin labeled Neurospora mitochondria. Biophys. J. 10, 618-629.
16. Kennedy L. and Baynes J. W. (1984) Non-enzymatic glycosylation and the chronic complications of diabetes: an overview. Diabetologia 26, 93-98.
17. Kennedy L. and Lyons T. J. (1989) Non-enzymatic glycosylation. Br. Med. Bull. 45, 174-190.
18. Lapolla A., Calabro A., Gerhardinger C., Dalfra M. G., Franchin A., Fedele D. and Crepaldi G. (1991) Glycated erythrocyte membrane proteins and haemorheological parameters in insulin dependent diabetic subjects. Clin. Hemorheol. 11, 405-415.
19. Leslie J., Williams D. L. and Gorin G. (1962) Determination of mercapto groups in proteins with N-ethylmaleimide. Anal. Biochem. 3, 257-263.
20. Macrury S. M., Lockhart J. C., Small M., Weir A, I., MacCuish A. C. and Lowe G. D. (1991) Do rheological variables play a role in diabetic peripheral neuropathy? Diabetic Med. 8, 232-236.
21. Maeda T., Akiyama M., Ashikaga M., Yokose T. and Isogal Y. (1982) Red cell filterability and internal viscosity in diabetic microangiopathy. Microvasc. Res. 24, 216.
22. McMillan D. E. (1976) Plasma protein changes, blood viscosity and diabetic microangiopathy. Diabetes 25, 858-864.
23. McMillan D. E., Utterback N. G. and La Puma J. (1978) Reduced erythrocyte deformability in diabetes. Diabetes 27, 895-901.
24. McMillan D. E. (1983) The effect of diabetes on blood flow properties. Diabetes 32, 56-63.
25. McMillan D. E. (1990) The role of blood flow in diabetic vascular disease. In Diabetes Mellitus: Theory and Practice (Eds Rifkin H. and Porte D., Jr). pp. 234-248. Elsevier. New York.
26. McMillan D. E. (1993) Hemorheological studies in the diabetes control and complications trial. Clin. Hemorheol. 13, 147-154.
27. Morse P. D. (1986) Determining intracellular viscosity from the rotational motion of spin labels. Meth. Enzymol. 127, 239-249.
28. Morse P. D. and Warth J. A. (1990) Direct measurement of the internal viscosity of sickle erythrocytes as a function of cell density. Biochim. Biophys. Acta 1053, 49-55.
29. Norton J. M., Barker N. D. and Rand P. W. (1981) Effect of cell geometry, internal viscosity and pH on erythrocyte filterability. Proc. Soc. Exp. Biol. Med. 166, 449-456.
30. Samaja M., Melotti D., Carenini A. and Pozza G. (1982) Glycosylated haemoglobins and the oxygen affinity of whole blood. Diabetologia 23, 399-402.
31. Siegel S. and Castellan N. J., Jr (1988) Nonparametric Statistics for the Behavioral Sciences. McGraw-Hill, New York.
32. Tentori L., Vivaldi G., Carts S., Salvati A. M., Sorcini M. and Valami S. (1965) The hemoglobin of Amphibia. II. Characterization of the hemoglobin of Rana esculenta: physicochemical properties and amino acid composition. Arch. Biochem. Biophys. 109, 404-414.
33. Vanboekel M. A. (1991) The role of glycation in aging and diabetes mellitus. Mol. Biol. Rep. 15, 57-64.
34. Vlassara H., Brownlee M. and Cerami A. (1986) Nonenzymatic glycosylation: role in the pathogenesis of diabetic complications. Clin. Chem. 32, 1337-1341.
35. Watala C. (1992) Hyperglycaemia alters the physico-chemical properties of proteins in erythrocyte membranes of diabetic patients. Int. J. Biochem. 24, 1755-1761.
36. Watala C., Gwoździński K. and Malek M. (1992a) Direct evidence for the alterations in protein structure and conformation upon in vitro nonenzymatic glycosylation. Int. J. Biochem. 24, 1295-1302.
37. Watala C., Witas H., Olszowska L. and Piasecki W. (1992b) The association between erythrocyte internal viscosity, protein non-enzymatic glycosylation and erythrocyte membrane dynamic properties in juvenile diabetes-mellitus. Int. J. Exp. Pathol. 73, 655-663.
38. Watala C., Pietrucha T., Gwoździński K. and Cierniewski C. S. (1993) Do the spectra of maleimide spin labelled whole blood platelets reflect the structure and conformation of membrane proteins? - The distribution of maleimide spin label in blood platelet proteins. J. Biochem. Biophys. Meth. 27, 157-165.
39. Wieland O. H. (1983) Protein modification by non-enzymatic glycosylation: possible role in the development of diabetic complications. Mol. Cell. Endocrinol. 29, 125-131.
40. Zar J. (1984) Biostatistical Analysis. Prentice-Hall, Englewood Cliffs, NJ.