Anxiolytic-like effects of metabotropic glutamate antagonist (RS)-α-methylserine-O-phosphate in rats

Polish Journal of Pharmacology

Volumn 48, Issue 5, 1996, Pages 507-509

  Chojnacka Wójcik, Ewa ^a   Tatarczyńska, Ewa ^a   Pilc, Andrzej ^a  

^a INSTITUTE OF PHARMACOLOGY   (Poland)

Author keywords

drinking conflict test; intrahippocampal injections; metabotropic glutamate receptors

Indexed keywords

ALPHA METHYLSERINE O PHOSPHATE; ALPHA METHYLSERINE O PHOSPHATE MONOPHENYL ESTER; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR ANTAGONIST; METABOTROPIC RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR; CONFLICT; CONTROLLED STUDY; HIPPOCAMPUS; INTRACEREBRAL DRUG ADMINISTRATION; MALE; MICROINJECTION; NONHUMAN; RAT; TRANQUILIZING ACTIVITY;

ANIMALS; ANTI-ANXIETY AGENTS; CONFLICT (PSYCHOLOGY); DRINKING BEHAVIOR; HIPPOCAMPUS; MALE; MICROINJECTIONS; ORGANOPHOSPHORUS COMPOUNDS; RATS; RATS, WISTAR; RECEPTORS, METABOTROPIC GLUTAMATE; SERINE;

EID: 0030476801     PISSN: 12306002     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Danysz W., Parsons C. G., Bresnik I., Quack G.: Glutamate in CNS Disorders. Drug News & Perspectives, 1996, 8, 261-277.
2. Jessa M., Nazar M., Bidziński A., Plaźnik A.: The effects of repeated administration of diazepam, MK-801 and CGP 37849 on rat behavior in two models of anxiety. Eur. Neuropsychopharmacol., 1996, 6, 55-61.
3. 2+-independent PKC subspecies modulates NMDAR1 current 1996. Neuroreport, 1996, 7, 477-480.
4. Pilc A., Legutko B.: The influence of prolonged anti-depressant treatment on the changes in cyclic AMP accumulation induced by excitatory amino acids in rat cerebral cortical slices. Neuroreport, 1995, 7, 85-88.
5. Pin J. P., Duvoisin R.: The metabotropic glutamate receptors: structure and functions. Neuropharmacology, 1995, 34, 1-26.
6. Przegaliński E., Tatarczyńska E., Dereń-Wesolek A., Chojnacka-Wójcik E.: Anticonflict effects of a competitive NMDA receptor antagonists and partial agonist at strychnine insensitive glycine receptors. Pharmacol. Biochem. Behav. 1996, 54, 73-79.
7. Thomas N. K., Jane D. E., Tse H-W., Watkins J. C.: Serine-O-phosphate derivatives as novel, potent and selective metabotropic glutamate receptor (mGluR) antagonists. Society for Neuroscience, 25-th Ann. Meet., Abstr., 1995, 251.12
8. Vogel J. R., Beer B., Clody D. E.: A simple and reliable conflict procedure for testing anti-anxiety agents, Psychophannacologia (Berlin), 1971, 21, 1-7.