-
1
-
-
0026447203
-
Emphysema: The first two centuries - and beyond: a historical overview, with suggestions for future research
-
Snider GL. Emphysema: the first two centuries - and beyond: a historical overview, with suggestions for future research. Am Rev Respir Dis 1992; 146:1354-44, 1615-22
-
(1992)
Am Rev Respir Dis
, vol.146
, pp. 1354-1444
-
-
Snider, G.L.1
-
3
-
-
0023899080
-
Alpha-1-antitrypsin augmentation therapy for alpha-1-antitrypsin deficiency
-
Hubbard RC, Crystal RG. Alpha-1-antitrypsin augmentation therapy for alpha-1-antitrypsin deficiency. Am J Med 1988; 84(suppl 6A):52-62
-
(1988)
Am J Med
, vol.84
, Issue.SUPPL. 6A
, pp. 52-62
-
-
Hubbard, R.C.1
Crystal, R.G.2
-
4
-
-
0023899706
-
Inactivation of viruses in therapeutic products derived from human plasma
-
Mitra G, Dobkin MB, Louie RE, et al. Inactivation of viruses in therapeutic products derived from human plasma. Am J Med 1988; 84(suppl 6A):87-90
-
(1988)
Am J Med
, vol.84
, Issue.SUPPL. 6A
, pp. 87-90
-
-
Mitra, G.1
Dobkin, M.B.2
Louie, R.E.3
-
5
-
-
0018800894
-
The oxidative inactivation of human α1-proteinase inhibitor
-
Johnson D, Travis J. The oxidative inactivation of human α1-proteinase inhibitor. J Biol Chem 1979; 254:4022-26
-
(1979)
J Biol Chem
, vol.254
, pp. 4022-4026
-
-
Johnson, D.1
Travis, J.2
-
6
-
-
0021919760
-
Elastases and emphysema: Current assessment of the protease-antiprotease hypothesis
-
Janoff A. Elastases and emphysema: current assessment of the protease-antiprotease hypothesis. Am Rev Respir Dis 1985; 132:417-34
-
(1985)
Am Rev Respir Dis
, vol.132
, pp. 417-434
-
-
Janoff, A.1
-
7
-
-
0018611004
-
Cigarette smoking induces functional antiprotease deficiency in the lower respiratory tract of humans
-
Gadek JE, Fells GA, Crystal RG. Cigarette smoking induces functional antiprotease deficiency in the lower respiratory tract of humans. Science 1979; 206:1315-16
-
(1979)
Science
, vol.206
, pp. 1315-1316
-
-
Gadek, J.E.1
Fells, G.A.2
Crystal, R.G.3
-
8
-
-
0025897211
-
Risk factors for emphysema: Cigarette smoking is associated with reduction in the association rate constant of lung α1-antitrypsin for neutrophil elastase
-
Ogushi F, Hubbard RC, Vogelmeier C, et al. Risk factors for emphysema: cigarette smoking is associated with reduction in the association rate constant of lung α1-antitrypsin for neutrophil elastase. J Clin Invest 1991; 87:1060-65
-
(1991)
J Clin Invest
, vol.87
, pp. 1060-1065
-
-
Ogushi, F.1
Hubbard, R.C.2
Vogelmeier, C.3
-
9
-
-
0021769165
-
Expression of human α1-antitrypsin in Escherichia coli
-
Bollen A, Loriau R, Herzog A, et al. Expression of human α1-antitrypsin in Escherichia coli. FEBS Lett 1984; 166:67-70
-
(1984)
FEBS Lett
, vol.166
, pp. 67-70
-
-
Bollen, A.1
Loriau, R.2
Herzog, A.3
-
10
-
-
0010730762
-
High-level production of biologically active human α1-antitrypsin in Escherichia coli
-
Courtney M, Buchwalder A, Tessier LH, et al. High-level production of biologically active human α1-antitrypsin in Escherichia coli. Proc Natl Acad Sci USA 1984; 81:669-73
-
(1984)
Proc Natl Acad Sci USA
, vol.81
, pp. 669-673
-
-
Courtney, M.1
Buchwalder, A.2
Tessier, L.H.3
-
11
-
-
0022187010
-
Evaluation of recombinant DNA-directed E coli-produced α1-antitrypsin as an anti-neutrophil elastase for potential use as replacement therapy of α1-antitrypsin deficiency
-
Straus SD, Fells GA, Wewers MD, et al. Evaluation of recombinant DNA-directed E coli-produced α1-antitrypsin as an anti-neutrophil elastase for potential use as replacement therapy of α1-antitrypsin deficiency. Biochem Biophys Res Commun 1985; 130:117-84
-
(1985)
Biochem Biophys Res Commun
, vol.130
, pp. 117-184
-
-
Straus, S.D.1
Fells, G.A.2
Wewers, M.D.3
-
12
-
-
0021188622
-
Synthesis in yeast of a functional oxidant-resistant mutant of human α1-antitrypsin
-
Rosemberg S, Barr PJ, Najarian RC, et al. Synthesis in yeast of a functional oxidant-resistant mutant of human α1-antitrypsin. Nature 1984; 312:77-80
-
(1984)
Nature
, vol.312
, pp. 77-80
-
-
Rosemberg, S.1
Barr, P.J.2
Najarian, R.C.3
-
13
-
-
0021956126
-
Isolation and properties of recombinant DNA-produced variants of human oil-proteinase inhibitor
-
Travis J, Owen M, George P, et al. Isolation and properties of recombinant DNA-produced variants of human oil-proteinase inhibitor. J Biol Chem 1985; 260:4384-89
-
(1985)
J Biol Chem
, vol.260
, pp. 4384-4389
-
-
Travis, J.1
Owen, M.2
George, P.3
-
14
-
-
0022944785
-
Altered specifities of genetically engineered α1-antitrypsin variants
-
Jallat S, Carvallo D, Tessier LH, et al. Altered specifities of genetically engineered α1-antitrypsin variants. Protein Eng 1986; 1:29-35
-
(1986)
Protein Eng
, vol.1
, pp. 29-35
-
-
Jallat, S.1
Carvallo, D.2
Tessier, L.H.3
-
15
-
-
0023546615
-
Z-type α1-antitrypsin is less competent than M1-type α1-antitrypsin as an inhibitor of neutrophil elastase
-
Ogushi F, Fells GA, Hubbard RC, et al. Z-type α1-antitrypsin is less competent than M1-type α1-antitrypsin as an inhibitor of neutrophil elastase. J Clin Invest 1987; 80:1366-74
-
(1987)
J Clin Invest
, vol.80
, pp. 1366-1374
-
-
Ogushi, F.1
Fells, G.A.2
Hubbard, R.C.3
-
16
-
-
8944238349
-
Discussion
-
Courtney M, Jallat S, Tessier LH, et al, eds. The construction of novel protease inhibitors by modification of the active centre of α1-antitrypsin.
-
Carrell RW. Discussion. In: Courtney M, Jallat S, Tessier LH, et al, eds. The construction of novel protease inhibitors by modification of the active centre of α1-antitrypsin. Phil Trans R Soc Lond A 1986; 317:381-90
-
(1986)
Phil Trans R Soc Lond A
, vol.317
, pp. 381-390
-
-
Carrell, R.W.1
-
17
-
-
0023588232
-
Augmentation of lung antineutrophil elastase capacity with recombinant human α-1-antitrypsin
-
Casolaro MA, Fells G, Wewers M, et al. Augmentation of lung antineutrophil elastase capacity with recombinant human α-1-antitrypsin. J Appl Physiol 1987; 63:2015-23
-
(1987)
J Appl Physiol
, vol.63
, pp. 2015-2023
-
-
Casolaro, M.A.1
Fells, G.2
Wewers, M.3
-
18
-
-
0025181026
-
1-proteinase inhibitor: Synthesis of polyethylene glycol conjugates with improved therapeutic potential
-
1-proteinase inhibitor: synthesis of polyethylene glycol conjugates with improved therapeutic potential. J Lab Clin Invest 1990; 116:58-65
-
(1990)
J Lab Clin Invest
, vol.116
, pp. 58-65
-
-
Mast, A.E.1
Salvesen, G.2
Schnebli, H.P.3
-
19
-
-
0021325847
-
Biological activity of recombinant interleukin-2 produced in e coli
-
Rosemberg SA, Grimm EA, McGrogan M. Biological activity of recombinant interleukin-2 produced in E coli. Science 1984; 223:1412-15
-
(1984)
Science
, vol.223
, pp. 1412-1415
-
-
Rosemberg, S.A.1
Grimm, E.A.2
McGrogan, M.3
-
20
-
-
0024495321
-
Fate of aerosolized recombinant DNA-produced α1-antitrypsin: Use of the epithelial surface of the lower respiratory tract to administer proteins of therapeutic importance
-
Hubbard RC, Casolaro MA, Mitchell M, et al. Fate of aerosolized recombinant DNA-produced α1-antitrypsin: use of the epithelial surface of the lower respiratory tract to administer proteins of therapeutic importance. Proc Natl Acad Sci USA 1989; 86:680-84
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 680-684
-
-
Hubbard, R.C.1
Casolaro, M.A.2
Mitchell, M.3
-
21
-
-
0026378633
-
Recombinant elastase inhibitors for therapy
-
Schnebli HP. Recombinant elastase inhibitors for therapy. Ann NY Acad Sci 1991; 624:212-18
-
(1991)
Ann NY Acad Sci
, vol.624
, pp. 212-218
-
-
Schnebli, H.P.1
-
22
-
-
0024417082
-
Recombinant DNA-produced α1-antitrypsin administered by aerosol augments lower respiratory tract antineutrophil elastase defenses in individuals with α1-antitrypsin deficiency
-
Hubbard RC, McElvaney NG, Sellers SE, et al. Recombinant DNA-produced α1-antitrypsin administered by aerosol augments lower respiratory tract antineutrophil elastase defenses in individuals with α1-antitrypsin deficiency. J Clin Invest 1989; 84:1349-54
-
(1989)
J Clin Invest
, vol.84
, pp. 1349-1354
-
-
Hubbard, R.C.1
McElvaney, N.G.2
Sellers, S.E.3
-
24
-
-
0021969054
-
1-antitrypsin variants of therapeutic potential for emphysema and thrombosis
-
1-antitrypsin variants of therapeutic potential for emphysema and thrombosis. Nature 1985; 313:149-51
-
(1985)
Nature
, vol.313
, pp. 149-151
-
-
Courtney, M.1
Jallat, S.2
Tessier, L.H.3
-
25
-
-
0021739085
-
1-antitrypsin protects connective tissue from neutrophil damage and may be useful in lung disease
-
1-antitrypsin protects connective tissue from neutrophil damage and may be useful in lung disease. Lancet 1984; 2:1426-28
-
(1984)
Lancet
, vol.2
, pp. 1426-1428
-
-
George, P.M.1
Vissers, M.C.M.2
Travis, J.3
-
26
-
-
0022638230
-
A genetically engineered, mutant human alpha-1-proteinase inhibitor is more resistant than the normal inhibitor to oxidative inactivation by chemicals, enzymes, cells, and cigarette smoke
-
Janoff A, George-Nascimento C, Rosemberg S. A genetically engineered, mutant human alpha-1-proteinase inhibitor is more resistant than the normal inhibitor to oxidative inactivation by chemicals, enzymes, cells, and cigarette smoke. Am Rev Respir Dis 1986; 133:353-56
-
(1986)
Am Rev Respir Dis
, vol.133
, pp. 353-356
-
-
Janoff, A.1
George-Nascimento, C.2
Rosemberg, S.3
-
28
-
-
0023571643
-
Oxidants spontaneously released by alveolar macrophages of cigarette smokers can inactivate the active site of α1-antitrypsin, rendering it ineffective as an inhibitor of neutrophil elastase
-
Hubbard RC, Ogushi F, Fells GA, et al. Oxidants spontaneously released by alveolar macrophages of cigarette smokers can inactivate the active site of α1-antitrypsin, rendering it ineffective as an inhibitor of neutrophil elastase. J Clin Invest 1987; 80:1289-95
-
(1987)
J Clin Invest
, vol.80
, pp. 1289-1295
-
-
Hubbard, R.C.1
Ogushi, F.2
Fells, G.A.3
-
30
-
-
0022551937
-
358→Arg) is a potent inhibitor of plasma kallikrein and activated factor XII fragment
-
358→Arg) is a potent inhibitor of plasma kallikrein and activated factor XII fragment. J Clin Invest 1985; 76:635-37
-
(1985)
J Clin Invest
, vol.76
, pp. 635-637
-
-
Schapira, M.1
Ramus, M.A.2
Jallat, S.3
-
31
-
-
0025671931
-
Alpha-1-antitrypsin variants produced by recombinant DNA: Differences in elastase inhibitory activity and resistance to oxidant agents
-
Luisetti M, Pozzi E, Diomede L, et al. Alpha-1-antitrypsin variants produced by recombinant DNA: differences in elastase inhibitory activity and resistance to oxidant agents. Int J Tissue React 1990; 12:363-68
-
(1990)
Int J Tissue React
, vol.12
, pp. 363-368
-
-
Luisetti, M.1
Pozzi, E.2
Diomede, L.3
-
32
-
-
0024247866
-
The functional role of acute phase plasma proteinase inhibitors
-
Travis J, Shieh BH, Potempa J. The functional role of acute phase plasma proteinase inhibitors. Tokai J Exp Clin Med 1988; 13:313-20
-
(1988)
Tokai J Exp Clin Med
, vol.13
, pp. 313-320
-
-
Travis, J.1
Shieh, B.H.2
Potempa, J.3
-
33
-
-
0027163296
-
The immunoevasive activities of Pseudomonas aeruginosa: Relevance for cystic fibrosis
-
Buret A, Cripps AW. The immunoevasive activities of Pseudomonas aeruginosa: relevance for cystic fibrosis. Am Rev Respir Dis 1993; 148:793-803
-
(1993)
Am Rev Respir Dis
, vol.148
, pp. 793-803
-
-
Buret, A.1
Cripps, A.W.2
-
34
-
-
0021254778
-
Purification of human plasma alpha-1-proteinase inhibitor and its inactivation by Pseudomonas aeruginosa elastase
-
Morihara K, Tsuzuki H, Harada M, et al. Purification of human plasma alpha-1-proteinase inhibitor and its inactivation by Pseudomonas aeruginosa elastase. J Biochem 1984; 95:795-805
-
(1984)
J Biochem
, vol.95
, pp. 795-805
-
-
Morihara, K.1
Tsuzuki, H.2
Harada, M.3
-
35
-
-
0027921714
-
358→Leu mutated α1-proteinase inhibitor as substrates of Pseudomonas aeruginosa elastase
-
358→Leu mutated α1-proteinase inhibitor as substrates of Pseudomonas aeruginosa elastase. Biochim Biophys Acta 1993; 1163:61-6
-
(1993)
Biochim Biophys Acta
, vol.1163
, pp. 61-66
-
-
Padrines, M.1
Bieth, J.G.2
-
36
-
-
0024790159
-
Variability of pulmonary function in alpha-1-antitrypsin deficiency: Clinical correlates
-
Silverman EK, Pierce JA, Province MA, et al. Variability of pulmonary function in alpha-1-antitrypsin deficiency: clinical correlates. Ann Intern Med 1989; 111:982-91
-
(1989)
Ann Intern Med
, vol.111
, pp. 982-991
-
-
Silverman, E.K.1
Pierce, J.A.2
Province, M.A.3
-
37
-
-
0024467067
-
Guidelines for the approach to the patient with severe hereditary alpha-1-antitrypsin deficiency
-
American Thoracic Society. Guidelines for the approach to the patient with severe hereditary alpha-1-antitrypsin deficiency. Am Rev Respir Dis 1989; 140:1494-97
-
(1989)
Am Rev Respir Dis
, vol.140
, pp. 1494-1497
-
-
-
39
-
-
0026408667
-
Neutrophil proteinases: Caution signs in designing inhibitors against enzymes with possible multiple functions
-
Travis J, Dubin A, Potempa J, et al. Neutrophil proteinases: caution signs in designing inhibitors against enzymes with possible multiple functions. Ann NY Acad Sci 1991; 624:81-6
-
(1991)
Ann NY Acad Sci
, vol.624
, pp. 81-86
-
-
Travis, J.1
Dubin, A.2
Potempa, J.3
-
40
-
-
0025782538
-
Potential problems in designing elastase inhibitors for therapy
-
Travis J, Fritz H. Potential problems in designing elastase inhibitors for therapy. Am Rev Respir Dis 1991; 143:1412-15
-
(1991)
Am Rev Respir Dis
, vol.143
, pp. 1412-1415
-
-
Travis, J.1
Fritz, H.2
-
41
-
-
0024602827
-
Tissue destruction by neutrophils
-
Weiss SJ. Tissue destruction by neutrophils. N Engl J Med 1989; 320:365-76
-
(1989)
N Engl J Med
, vol.320
, pp. 365-376
-
-
Weiss, S.J.1
|