Efficacy and side effects of beta2-agonists by inhaled route in acute asthma in children: Comparison of salbutamol, terbutaline, and fenoterol

Journal of Asthma

Volumn 33, Issue 6, 1996, Pages 407-415

  Scalabrin, Deolinda M F ^a,b   Solé, Dirceu ^a   Naspitz, Charles K ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b NONE   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; FENOTEROL; SALBUTAMOL; TERBUTALINE;

ADOLESCENT; ARTICLE; ASTHMA; BLOOD PRESSURE; BREATHING RATE; BRONCHODILATATION; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; FORCED EXPIRATORY VOLUME; HEART RATE; HUMAN; INHALATIONAL DRUG ADMINISTRATION; LUNG FUNCTION; MALE; NEBULIZATION; RANDOMIZED CONTROLLED TRIAL; SCHOOL CHILD; SINGLE BLIND PROCEDURE; SPIROMETRY; TACHYCARDIA; TREMOR;

EID: 0030475813     PISSN: 02770903     EISSN: None     Source Type: Journal    
DOI: 10.3109/02770909609068185     Document Type: Article

References (21)

1. Sly RM: Changing asthma mortality and sales of inhaled bronchodilators and anti-asthmatic drugs. Ann Allergy 73: 439-443 (1994).
2. Pearce N, Beasley R, Crane J, Burgess C, Jackson R: End of the New Zealand asthma mortality epidemic. Lancet 345:41-44 (1995).
3. Spitzer WO, Suisse S, Ernst P, Horwitz RI, Habbick B, Cockroft D, Boivin JF, McNutt M, Buist AS, Rebuck AS: The use of beta-agonists and the risk of death and near death from asthma. N Engl J Med 326:501-506 (1992).
4. 2-agonists and death from asthma. J Allergy Clin Immunol 93:677 (1994).
5. National Institutes of Health: Global Strategy for Asthma Management and Prevention: NHLBI/WHO Workshop Report, Publication no. 95-3659, January 1995.
6. Flatt A, Crane J, Purdie G, Kwong T, Beasley R, Burgess C: The cardiovascular effects of beta adrenergic agonist drugs administered by nebulisation. Postgrad Med J 66:98-101 (1990).
7. Wong CS, Pavord ID, Williams J, Britton JR, Tatters-field AE: Bronchodilator, cardiovascular, and hypokalaemic effects of fenoterol, salbutamol, and terbutaline in asthma. Lancet 336:1396-1399 (1990).
8. Ben-Zvi Z; Lam C, Hoffman J, Teets-Grimm KC, Kattan M: An evaluation of the initial treatment of acute asthma. Pediatrics 70:348-353 (1982)
9. Scalabrin DMF, Naspitz CK: Efficacy and side effects of salbutamol in acute asthma in children: Comparison of oral route and two different nebulizer systems. J Asthma 30:51-59 (1993).
10. Inoue H, Inoue C, Okayama M, Sekizawa K, Hida W, Takishima T: Breathing 30 per cent oxygen attenuates bronchial responsiveness to inhaled methacholine in asthmatic patients. Eur Respir J 2:506-512 (1989).
11. Schuh S, Reider MJ, Canny G, Pender E, Forbes T, Tan YK, Bailey D, Levison H: Nebulized albuterol in acute childhood asthma: Comparison of two doses. Pediatrics 86:509-513 (1990).
12. Salmeron S, Brochard L, Mal H, Tenaillon A, Henry-Amar M, Renon D, Duroux P, Simonneau G: Nebulized versus intravenous albuterol in hypercapnic acute asthma: A multicenter, double-blind, randomized study. Am J Respir Crit Care Med 149:1466-1470 (1994).
13. Gray BJ, Frame MH, Costello JF: A comparative double-blind study of the bronchodilator effects and side effects of inhaled fenoterol and terbutaline administered in equipotent doses. Br J Dis Chest 76:341-350 (1982).
14. Bellamy D, Penketh A: A cumulative dose comparison between salbutamol and fenoterol metered dose aerosols in asthmatic patients. Postgrad Med J 63:459-461 (1987).
15. König P, Hordvik NL, Sunderrajan EV: A comparison of inhaled fenoterol and albuterol in asthma. Ann Allergy 55 691-693 (1985).
16. Lipworth BJ, Clark RA, Dhillon DP, Moreland TA, Struthers AD, Clark GA, McDevitt DG: Pharmacokinetics, efficacy and adverse effects of sublingual salbutamol in patients with asthma. Eur J Clin Pharmacol 37:567-571 (1989).
17. Hörnblad Y, Ripe E, Magnusson PO, Tegnér K: The metabolism and clinical activity of terbutaline and its prodrug ibuterol. Eur J Clin Pharmacol 10:9-18 (1976).
18. Collier JG. Dobbs RJ, Williams I: Salbutamol aerosol causes a tachycardia due to the inhaled rather than the swallowed fraction. Br J Clin Pharmacol 9:273-274 (1980).
19. Küng M, Croley SW, Phillips BA: Systemic cardiovascular and metabolic effects associated with the inhalation of an increased dose of albuterol: Influence of mouth rinsing and gargling. Chest 91:382-387 (1987).
20. Enna SJ, Schanker LS: Absorption of drugs from the rat lung. Am J Physiol 223:1227-1231 (1972). 21.
21. Davies DS: The fate of inhaled terbutaline Eur J Respir Dis 65:141-147 (1984)