Single shot with tetanus toxoid in biodegradable microspheres protects mice despite acid-induced denaturation of the antigen

Vaccine

Volumn 14, Issue 17-18, 1996, Pages 1627-1632

  Kersten, Gideon F A ^a   Donders, Dian ^a   Akkermans, Arnoud ^a   Beuvery, E Coen ^a  

^a NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

Author keywords

microsphere; poly(lactide co glycolide); tetanus toxoid

Indexed keywords

BACTERIAL ANTIGEN; MICROSPHERE; TETANUS TOXOID;

ANIMAL EXPERIMENT; ARTICLE; BIODEGRADATION; CLOSTRIDIUM TETANI; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; ENCAPSULATION; IMMUNIZATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TETANUS;

ACIDS; ANIMALS; ANTIGENS, BACTERIAL; BIODEGRADATION, ENVIRONMENTAL; IMMUNIZATION SCHEDULE; LETHAL DOSE 50; MICE; MICROSPHERES; TETANUS TOXOID;

EID: 0030475711     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(96)00145-4     Document Type: Article

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