Synergistic effects of erythropoietin and interleukin-6 on the in vitro proplatelet process formation of rat megakaryocytes

Pathology International

Volumn 46, Issue 12, 1996, Pages 968-976

  Tange, Tsuyoshi ^a   Miyazaki, Hiroshi ^b  

^a UNIVERSITY OF TOKYO   (Japan)

^b KIRIN BREWERY CO LTD   (Japan)

Author keywords

erythropoietin; interleukin 6; megakaryocyte; proplatelet process formation; thrombopoietin

Indexed keywords

ACTIVIN A; LEUKEMIA INHIBITORY FACTOR; POLYCLONAL ANTIBODY; RECOMBINANT ERYTHROPOIETIN; RECOMBINANT INTERLEUKIN 11; RECOMBINANT INTERLEUKIN 6;

ANIMAL CELL; ARTICLE; BONE MARROW; CELL DIFFERENTIATION; CELL MATURATION; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; HEMATOPOIESIS; MEGAKARYOCYTE; NONHUMAN; PRIORITY JOURNAL; RAT; THROMBOCYTOPOIESIS;

EID: 0030475669     PISSN: 13205463     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1827.1996.tb03576.x     Document Type: Article

References (50)

1. Evatt BL, Levin J, Algazy KM. Partial purification of thrombopoietin from the plasma of thrombocytopenic rabbits. Blood 1979; 54: 377-388.
2. Straneva JE, Yang HH, Hui SL, Bruno E, Hoffman R. Effects of megakaryocyte colony-stimulating factor on terminal cytoplasmic maturation of human megakaryocytes. Exp. Hematol. 1987; 15: 657-663.
3. Williams N, Oon SH, Jackson H, Lim R. Studies on megakaryocyte potentiator: Its production and some biochemical characteristics. In: Levine RF, Williams N, Levin J, Evatt BL, eds. Megakaryocyte Development and Function. Alan R Liss, New York, 1986; 91-103.
4. Kaushansky K, Lok S, Holly RD et al. Promotion of megakaryocyte progenitor expansion and differentiation by the C-Mpl ligand thrombopoietin. Nature 1994; 369: 568-571.
5. Wendung F, Maraskovsky E, Debili N et al. C-Mpl ligand is a humoral regulator of megakaryocytopoiesis. Nature 1994; 369: 571-574.
6. Kato T, Ogami K, Shimada Y et al. Purification and characterization of thrombopoietin. J. Biochem. (Tokyo) 1995; 118: 229-236.
7. Lotem J, Shabo Y, Sachs L. Regulation of megakaryocyte development by interleukin-6. Blood 1989; 74: 1545-1551.
8. Hill RJ, Warren MK, Stenberg P et al. Stimulation of megakaryocytopoiesis in mice by human recombinant interleukin-6. Blood 1991; 77: 42-48.
9. Leven RM, Rodrigeuz A. Immunomagnetic bead isolation of megakaryocytes from guinea-pig bone marrow: Effect of recombinant interleukin-6 on size, ploidy and cytoplasmic fragmentation. Br. J. Haematol. 1991; 77: 267-273.
10. Ishibashi T, Kimura H, Shikama Y et al. Interleukin-6 is a potent thrombopoietic factor in vivo in mice. Blood 1989; 74: 1241-1244.
11. Vainchenker W, Bouguet J, Guichard J, Breton-Gorius J. Megakaryocyte colony formation from human bone marrow precursors. Blood 1979; 54: 940-945.
12. Choi SI, Simone JV. Platelet production in experimental iron deficiency anemia. Blood 1973; 42: 219-228.
13. Berridge MV, Fraser JK, Carter JM, Lin FK. Effects of recombinant human erythropoietin on megakaryocytes and on platelet production in the rat. Blood 1988; 72: 970-977.
14. Semenza GL, Traystman MD, Gearhart JD, Antonarakis SE. Polycythemia in transgenic mice expressing the human erythropoietin gene. Proc. Natl Acad. Sci. USA 1989; 86: 2301-2305.
15. McDonald TP, Clift RE, Cottrell MB. Large, chronic doses of erythropoietin cause thrombocytopenia in mice. Blood 1992; 80: 352-358.
16. Leven RM, Yee MK. Megakaryocyte morphogenesis stimulated in vitro by whole and partially fractionated thrombocytopenic plasma: A model system for the study of platelet formation. Blood 1987; 69: 1046-1052.
17. Topp KS, Tablin F, Leven J. Culture of isolated bovine megakaryocytes on reconstituted basement membrane matrix leads to proplatelet process formation. Blood 1990; 76: 912-924.
18. Muto M. A scanning and transmission electron microscopic study on rat bone marrow sinuses and transmural migration of blood cells. Arch. Histol. Jpn. 1976; 39: 51-66.
19. Radley JM, Scurfield G. The mechanism of platelet release. Blood 1980; 56: 996-999.
20. Tanaka H, Ishida Y, Kaneko T, Matsumoto N. Isolation of human megakaryocytes by immunomagnetic beads. Br. J. Haematol. 1989; 73: 18-22.
21. Miyazaki H, Tamura S, Sudo T, Suzuki T. Production and characterization of monoclonal antibodies against rat platelet GpIIb/IIIa. Thromb. Res. 1990; 59: 941-953.
22. Nagasawa T, Nakazawa M, Abe T. Proliferation and maturation of murine megakaryocyte progenitor cells in a liquid culture system. Exp. Hematol. 1985; 13: 51-58.
23. Hirano T, Yasukawa K, Harada H et al. Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin. Nature 1986; 324: 73-76.
24. Taga T, Kawanishi Y, Hardy RR, Hirano T, Kishimoto T. Receptors for B cell stimulatory factor 2: Quantitation, specificity, distribution, and regulation of their expression. J. Exp. Med. 1987; 166: 967-981.
25. Lin F-K, Suggs S, Lin C-H et al. Cloning and expression of the human erythropoietin gene. Proc. Natl Acad. Sci. USA 1985; 82: 7580-7584.
26. Murata M, Eto Y, Shibai H, Sakai M, Muramatsu M. Erythroid differentiation factor is encoded by the same mRNA as that of the inhibin A chain. Proc. Natl Acad. Sci. USA 1988; 85: 2434-2438.
27. Moreau JF, Donaldson DD, Bennett F, Witek-Giannotti J, Clark SC, Wong GG. Leukemia inhibitory factor is identical to the myeloid growth factor human interleukin for DA cells. Nature 1988; 336: 690-692.
28. Paul SR, Bennett F, Calvetti JA et al. Molecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokine. Proc. Natl Acad. Sci. USA 1990; 87: 7512-7516.
29. Hirano T, Matsuda T, Hosoi K, Okano A, Matsui H, Kishimoto T. Absence of antiviral activity in recombinant B cell stimulating factor (BSF-2). Immunol. Lett. 1988; 17: 41-45.
30. Tange T. Serum free coculture condition for proplatelet process formation (PPF) by megakaryocytes. Med. Biol. 1994; 129: 157-161.
31. Tange T, Hasegawa Y, Oka T et al. Establishment and characterization of a new human mesothelioma cell line (T-85) from malignant peritoneal mesothelioma with remarkable thrombocytosis. Pathol. Int. 1995; 45: 791-800.
32. Andrews RG, Bartelmez SH, Egrie J, Bernstein ID, Zsebo K. Recombinant human stem cell factor (rhSCF) stimulates in vitro and in vivo hematopoiesis in baboons (Abstract). Blood 1990; 76 (Suppl. 1): 130a, 509.
33. Gancer A, Seipelt G, Lindemann A et al. Effects of recombinant human interleukin-3 in patients with myelodysplastic syndromes. Blood 1990; 76: 455-462.
34. Metcalf D, Nicola NA, Gearing DP. Effects of injected leukemia inhibitory factor in hematopoietic and other tissues in mice. Blood 1990; 76: 50-56.
35. Tewari A, Buhles W Jr. Preliminary report: Effects of interleukin-1 on platelet counts. Lancet 1990; 336: 712-716.
36. Ishibashi T, Kimura H, Uchida T, Kariyone S, Friese P, Burstein SA. Human interleukin-6 is a direct promoter of maturation of megakaryocytes in vitro. Proc. Natl Acad. Sci. USA 1989; 86: 5953-5957.
37. Goldman S, Loebelanz J, McCarthy K et al. Recombinant human interleukin-11 (rhlL-11) stimulates megakaryocyte maturation and increase in peripheral platelet number in vivo (Abstract). Blood 1991; 78 (Suppl. 1): 132a, 518.
38. Teramura M, Kobayashi S, Hoshino S, Oshimi K, Mizoguchi H. Interleukin-11 enhances human megakaryocytopoiesis in vitro. Blood 1992; 79: 327-331.
39. Yonemura Y, Kawakita M, Masuda T, Fujimoto K, Kato K, Takatsuki K. Synergistic effects of interleukin-3 and interleukin-11 on murine megakaryopoiesis in serum-free culture. Exp. Hematol. 1992; 20: 1011-1016.
40. Burstein SA, Mei J, Henthorn J, Friese P, Turner K. Recombinant human leukemia inhibitory factor (LIF) and interleukin-11 (IL-11) promote murine and human megakaryocytopoiesis in vitro (Abstract). Blood 1990; 76 (Suppl. 1): 450a, 1789.
41. Hill RJ, Warren MK, Levin J, Gauldie J. Evidence that interleukin-6 does not play a role in the stimulation of platelet production after induction of acute thrombocytopenia. Blood 1992; 82: 346-351.
42. Yamashita T, Shimizu T, Ogata E. Activin A/erythroid differentiation factor induces thromboxane A2 synthetic activity in murine erythroleukemia cells. J. Biol. Chem. 1991; 266: 3888-3892.
43. Tsukada J, Misago M, Kikuchi M et al. Interactions between recombinant human erythropoietin and serum factor(s) on murine megakaryocyte colony formation. Blood 1992; 80: 37-45.
44. Leven RM, Tablin F. Extracellular matrix stimulation of guinea pig megakaryocyte proplatelet formation in vitro is mediated through the vitronecin receptor. Exp. Hematol. 1992; 20: 1316-1322.
45. Tange T, Miyazaki H. Thrombopoietic activity of recombinant factors (Abstract). J. Cell. Biochem. 1993; 17 (Suppl.): 70.
46. Hunt P, Hokom MM, Hornkohl A, Wiemann B, Rohide MF, Arakawa T. The effect of the platelet-derived glycosaminogly-canserglycin on in vitro proplatelet-like process formation. Exp. Hematol. 1993; 21: 1295-1304.
47. Inoue H, Ishii H, Tsutsumi M et al. Growth factor-induced process formation of megakaryocytes derived from CFU-MK. Br. J. Haematol. 1993; 85: 260-269.
48. Debili N, Wending F, Katz A et al. The Mpl-ligand or thrombopoietin or megakaryocyte growth and differentiative factor has both direct proliferative and differentative activities on human megakaryocyte progenitors. Blood 1995; 86: 2516-2525.
49. Kobayashi M, Laver JH, Kato T, Miyazaki H, Ogawa M. Recombinant human thrombopoietin (Mpl ligand) enhances proliferation of erythroid progenitors. Blood 1995; 86: 2494-2499.
50. Kaushansky K, Lin N, Grossmann A, Humes J, Sprugel KH, Broudy VC. Thrombopoietin expands erythroid, granulocyte-macrophage, and megakaryocytic progenitor cells in normal and myelosuppressed mice. Exp. Hematol. 1996; 24: 265-269.