Selective tumor irradiation by infusional brachytherapy in nonresectable pancreatic cancer: A phase I study

International Journal of Radiation Oncology Biology Physics

Volumn 36, Issue 5, 1996, Pages 1117-1126

  Order, Stanley E ^a,b   Siegel, Jeffery A ^a,b   Principato, Robert ^a,b   Zeiger, Louis E ^a,b   Johnson, Elizabeth ^a,b   Lang, Patricia ^a,b   Lustig, Robert ^a,b   Wallner, Paul E ^a,b  

^a Department of Anesthesiology   (United States)

^b RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

Brachytherapy; Colloidal 32P; Nonresectable Pancreas; Phase I

Indexed keywords

CHROMIUM PHOSPHATE P 32; CREATININE; DEXAMETHASONE; FLUOROURACIL; MACROSALB TC 99M; PHOSPHOCOL; PROTHROMBIN; THROMBOPLASTIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BIOPSY; BRACHYTHERAPY; CANCER RADIOTHERAPY; CLINICAL ARTICLE; CLINICAL PROTOCOL; CLINICAL TRIAL; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; INFUSION; INTERSTITIAL RADIATION; INTRATUMORAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; METASTASIS; MULTICENTER STUDY; PANCREAS CANCER; PHASE 1 CLINICAL TRIAL; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; RADIATION DOSE;

ADULT; AGED; BRACHYTHERAPY; FEMALE; HUMANS; MALE; MIDDLE AGED; PANCREATIC NEOPLASMS; SURVIVAL RATE; TOMOGRAPHY, X-RAY COMPUTED;

EID: 0030475411     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(96)00484-1     Document Type: Article

References (17)

1. 1. Banfi, G.; Zerbi, A.; Paston, S.; Paiolini, D.; DiCarlo, P.; Bonini, P. Behavior of tumor markers CA19-9, CA195, CAM43, CA242 and TPS in the diagnosis and follow-up of pancreatic cancer. Clin. Chem. 39:420-423; 1993.
2. 2. Bernard, E. J.; Nour, R.; Bulter, P.; Quinn, R. J. Incidents of pulmonary embolism in single segmental mismatch on lung scanning. J. Nucl. Med. 35:1928-1931; 1994.
3. 3. Dobelbower, R. R., Jr.; Havard, J. M.; Bagne, F. R.; Eltaki, A.; Merrick, H. W., III Treatment of cancer of the pancreas by precision high dose (PHD) external photon beam and intraoperative electron beam therapy (IOEBT). Int. J. Radiat. Oncol. Biol. Phys. 16:205-209; 1989.
4. 4. Jain, R. K. Transport of molecules in the tumor interstitium: A review. Can. Res. 47:3039-3051; 1987.
5. 5. Komaki, R.; Wadler, S.; Peters, T.; Byhardt, R. W.; Order, S. E.; Gallagher, M. J.; Herskovic, A.; Pederson, J. High-dose local irradiation plus prophylactic hepatic irradiation and chemotherapy for inoperable adenocarcinoma of the pancreas. Cancer 69:1505-1509; 1992.
6. 32P in New Zealand rabbits. Radiology 134:729-734; 1980.
7. 32P injected into the portal vein of dogs and man. Cancer 10:164-171; 1957.
8. 8. Nguyen, H.; Lemort, M.; Anduy, G.; Badr-El-Din, A.; Roelandts, M.; Verbast, A.; Destosses, F.; Simon, S.; Wallner, J.; Siegel, J.; Lustig, R. A.; Van Route, P.; Fruhling, J.; Order, S. E. Infusional brachytherapy in the treatment of head and neck cancer: A preliminary report of three cases treated with this new radiation modality. Antib. Immunconj. Radiopharm. 7:155-169; 1994.
9. 9. Nightengale, T. E.; Gruber, J. Helicobacter and human cancer. J. Nat;. Cancer Inst. 86:1505-1509; 1994.
10. 10. Order, S. E.; Lustig, R.; Principato, R.; Wilner, H.; Zeiger, L. S.; Johnson, E.; Wallner, P. E. Infusional brachytherapy: Selective high-dose radiation in solid cancers. Am. Soc. Clin. Oncol. 14:482; 1995.
11. 11. Order, S. E.; Siegel, J. A.; Lustig, R. A.; Principato, R.; Zeiger, L.; Johnson, S.; Zhang, H.; Lang, P.; Pilchik, N. B.; Metz, J.; Denittis, A.; Boerner, P.; Beuerlein, G.; Wallner, P. E. A new method for delivering radioactive cytotoxic agents in solid cancers. Int. J. Radiat. Oncol. Biol. Phys. 30:715-720; 1994.
12. 12. Order, S. E.; Siegel, J. A.; Lustig, R. A.; Principato, R.; Zeiger, L.; Johnson, S.; Zhang, H.; Lang, P.; Wallner, P. E. Infusional brachytherapy in die treatment of non-resectable pancreatic cancer: A new radiation modality (preliminary report of the Phase I Study). Antib. Immunoconj. Radiopharm. 7:11-27; 1994.
13. 32phosphorous. Antib. Immunoconj. Radiopharm. 7:1-10; 1994.
14. 14. Siegel, J. A.; Zeiger, L. S.; Order, S. E.; Wallner, P. E. Quantitative bremsstrahlung single photon emission computer tomographic imaging: Use for volume activity and absorb dose calculations. Int. J. Radiat. Oncol. Biol. Phys. 31:953-958; 1995.
15. 15. Simonean, A.; Elfant, A.; Sanion, P.; Spielgel, T.; McCleery, C.; CanCora, B.; Order, S. E.; Peikin, S. Pancreatic cancer (PC) is associated with exposure to Heliocobacter pylori. J. Am. Gastroenter. Assoc. 110:A-595; 1996.
16. 16. Yang, N. C.; Leichner, P. K.; Fishman, E. K.; Siegelman, S. S.; Frenkel, T. L.; Wallace, J. R.; et al. CT volumetrics of primary cancers. J. Comp. Assist. Tomogr. 10:621-628; 1986.
17. 32P. Ann. Acad. Med. Singapore 25:347-351; 1996.