Studies on the synthesis and structure-activity relationships of 2-(2-functionalized pyrrolidin-4-ylthio)-1β-methylcarbapenems

Chemical and Pharmaceutical Bulletin

Volumn 44, Issue 12, 1996, Pages 2326-2330

  Lee, Hong Woo ^a   Kim, Eung Nam ^a   Son, Hoe Joo ^a   Ahn, Soon Kil ^a   Chung, Koo Hun ^a   Kim, Jung Woo ^a   Lee, Chong Ryoul ^a  

^a Chong Kun Dang Research Institute   (South Korea)

Author keywords

Antibacterial activity; Carbamoyl pyrrolidine; Dase I; Hydroxyethyl pyrrolidine; Lyophilization; Renal dehydropepti

Indexed keywords

2 [5 [4 (5 AMINO 2 HYDROXYPENTANOYL) 1 PIPERAZINYLCARBONYL] 3 PYRROLIDINYLTHIO] 6 (1 HYDROXYETHYL) 1 METHYL 1 CARBA 2 PENEM 3 CARBOXYLIC ACID; AMINOACYLASE; CARBAPENEM DERIVATIVE; LENAPENEM; MEROPENEM; PANIPENEM; THIENAMYCIN;

ARTICLE; BACTERICIDAL ACTIVITY; CONTROLLED STUDY; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; FREEZE DRYING; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PSEUDOMONAS AERUGINOSA; STRUCTURE ACTIVITY RELATION;

ANIMALS; CARBAPENEMS; CHROMATOGRAPHY, THIN LAYER; DIPEPTIDASES; KIDNEY; MASS SPECTROMETRY; MICROBIAL SENSITIVITY TESTS; PSEUDOMONAS AERUGINOSA; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030475180     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.44.2326     Document Type: Article

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