The Bcg gene (Nramp1) does not determine resistance of mice to virulent Mycobacterium tuberculosis

Annals of the New York Academy of Sciences

Volumn 797, Issue , 1996, Pages 257-259

  Medina, Eva ^a   North, Robert J ^a  

^a TRUDEAU INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; CHROMOSOME 1; CONFERENCE PAPER; GENE; INFECTION RESISTANCE; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; TUBERCULOSIS;

ANIMALIA; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS;

EID: 0030475127     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1996.tb52970.x     Document Type: Conference Paper

References (5)

1. VIDAL, S. M., D. MALO, K. VOGAN, E. SKAMENE & P. GROS. 1993. Natural resistance to infection with intracellular parasites: Identification of a candidate gene for Bcg. 73: 469-485.
2. VIDAL, S., M. L. TREMBLAY, G. GOVONI, S. GAUTHIER, G. SEBASTIANI, D. MALO, E. SKAMENE, M. OLIVER, S. JOTHY & P. GROS. 1995. The Ity/Lsh/Bcg locus: Natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp gene. J. Exp. Med. 182:
3. SKAMENE, E., P. GROS, A. GORGET, P. A. L. KONGSHAVN, C. S. CHARLES & B. A. TAYLOR. 1982. Genetic regulation of resistance to intracellular pathogens. Nature 297: 506-509.
4. DUNN, P. L. & R. J. NORTH. 1995. Virulence ranking of some Mycobacterium tuberculosis and Mycobacterium bovis strains according to their ability to multiply in the lungs, induce lung pathology, and cause mortality in mice. Infect. Immun. 63: 3428-3437.
5. HOPEWELL, P. C. 1994. Overview of clinical tuberculosis. In Tuberculosis: Pathogenesis, Protection and Control. B. R. Bloom, Eds. 25-16. ASM Press, Washington DC.