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Volumn 795, Issue , 1996, Pages 294-309

Cellular and molecular mechanisms underlying IL-12-induced tumor regression

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; MESSENGER RNA; MONOCLONAL ANTIBODY; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; RECOMBINANT INTERLEUKIN 12; SPHINGOMYELIN;

EID: 0030473466     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1996.tb52679.x     Document Type: Conference Paper
Times cited : (35)

References (47)
  • 1
    • 0024467154 scopus 로고
    • Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biological effects on human lymphocytes
    • KOBAYASHI, M., L. FITZ, M. RYAN, R. M. HEWICK, S. C. CLARK, S. CHAN, R. LOUDON, F. SHERMAN, B. PERUSSIA & G. TRINCHIERI. 1989. Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biological effects on human lymphocytes. J. Exp. Med. 170: 827-845.
    • (1989) J. Exp. Med. , vol.170 , pp. 827-845
    • Kobayashi, M.1    Fitz, L.2    Ryan, M.3    Hewick, R.M.4    Clark, S.C.5    Chan, S.6    Loudon, R.7    Sherman, F.8    Perussia, B.9    Trinchieri, G.10
  • 3
    • 0026520178 scopus 로고
    • Responses of human natural killer (NK) cells to NK cell stimulatory factor (NKSF): Cytolytic activity and proliferation of NK cells are differentially regulated by NKSF
    • ROBERTSON, M. J., R. J. SOIFFER, S. F. WOLF, T. J. MANLEY, C. DONAHUE, D. YOUNG, S. H. HERRMANN & J. RITZ. 1992. Responses of human natural killer (NK) cells to NK cell stimulatory factor (NKSF): Cytolytic activity and proliferation of NK cells are differentially regulated by NKSF. J. Exp. Med. 175: 779-788.
    • (1992) J. Exp. Med. , vol.175 , pp. 779-788
    • Robertson, M.J.1    Soiffer, R.J.2    Wolf, S.F.3    Manley, T.J.4    Donahue, C.5    Young, D.6    Herrmann, S.H.7    Ritz, J.8
  • 5
    • 0026441372 scopus 로고
    • Natural killer (NK) cell stimulatory factor or IL-12 has differential effects on the proliferation of TCR-a +, TCR-y 8+ T lymphocytes and NK cells
    • PERUSSIA, B., S. H. CHAN, A. D'ANDREA, K. Tsuii, D. SANTOLI, M. POSPISIL, D. YOUNG, S. F. WOLF & G. TRINCHIERI. 1992. Natural killer (NK) cell stimulatory factor or IL-12 has differential effects on the proliferation of TCR-a +, TCR-y 8+ T lymphocytes and NK cells. J. Immunol. 149: 3495-3502.
    • (1992) J. Immunol. , vol.149 , pp. 3495-3502
    • Perussia, B.1    Chan, S.H.2    D'Andrea, A.3    Tsuii, K.4    Santoli, D.5    Pospisil, M.6    Young, D.7    Wolf, S.F.8    Trinchieri, G.9
  • 6
    • 0025819340 scopus 로고
    • Induction of interferon y production by natural killer cell stimulatory factor: Characterization of the responding cells and synergy with other inducers
    • CHAN, S. H., B. PERUSSIA, J. W. GUPTA, M. KOBAYASHI, M. POSPISIL, H. A. YOUNG, S. F. WOLF, D. YOUNG, S. C. CLARK & G. TRINCHIERI. 1991. Induction of interferon y production by natural killer cell stimulatory factor: Characterization of the responding cells and synergy with other inducers. J. Exp. Med. 173: 869-879.
    • (1991) J. Exp. Med. , vol.173 , pp. 869-879
    • Chan, S.H.1    Perussia, B.2    Gupta, J.W.3    Kobayashi, M.4    Pospisil, M.5    Young, H.A.6    Wolf, S.F.7    Young, D.8    Clark, S.C.9    Trinchieri, G.10
  • 7
    • 0027409793 scopus 로고
    • Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 [Thl]-specific immune responses and inhibits the development of IL-4-producing Th cells
    • MANETTI, R., P. PARRONCHI, M. G. GIUDIZI, M. P. PICCINNI, E. MAGGI, G. TRINCHIERI & S. ROMAGNANI. 1993. Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 [Thl]-specific immune responses and inhibits the development of IL-4-producing Th cells. J. Exp. Med. 177: 1199-1204.
    • (1993) J. Exp. Med. , vol.177 , pp. 1199-1204
    • Manetti, R.1    Parronchi, P.2    Giudizi, M.G.3    Piccinni, M.P.4    Maggi, E.5    Trinchieri, G.6    Romagnani, S.7
  • 8
    • 43949163341 scopus 로고
    • Interleukin-12 and its role in the generation of TH1 cells
    • TRINCHIERI, G. 1993. Interleukin-12 and its role in the generation of TH1 cells. Immunol. Today 14: 335-338.
    • (1993) Immunol. Today , vol.14 , pp. 335-338
    • Trinchieri, G.1
  • 11
    • 0029039610 scopus 로고
    • Systemic administration of rIL-12 induces complete tumor regression and protective immunity: Response is correlated with a striking reversal of suppressed interferon-y production by anti-tumor T cells
    • Zou,J. P., N. YAMAMOTO, T. FUJII, H.TAKENAKA, M. KOBAYASHI, S. H. HERRMANN, S. F. WOLF, H. FUJIWARA & T. HAMAOKA. 1995. Systemic administration of rIL-12 induces complete tumor regression and protective immunity: Response is correlated with a striking reversal of suppressed interferon-y production by anti-tumor T cells. Intl. Immunol. 7: 1135-1145.
    • (1995) Intl. Immunol. , vol.7 , pp. 1135-1145
    • Zou, J.P.1    Yamamoto, N.2    Fujii, T.3    Takenaka, H.4    Kobayashi, M.5    Herrmann, S.H.6    Wolf, S.F.7    Fujiwara, H.8    Hamaoka, T.9
  • 12
    • 0028944328 scopus 로고
    • Influence of interleukin 12 on p53 peptide vaccination against established Meth A sarcoma
    • NOGUCHI, Y., E. C. RICHARDS, Y. T. CHEN & L. J. OLD. 1995. Influence of interleukin 12 on p53 peptide vaccination against established Meth A sarcoma. Proc. Natl. Acad. Sci. USA 92: 2219-2223.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 2219-2223
    • Noguchi, Y.1    Richards, E.C.2    Chen, Y.T.3    Old, L.J.4
  • 18
    • 0344028594 scopus 로고
    • A sequence of cellular and molecular events involved in IL-12-induced tumor regression
    • FUJIWARA, H., J. P. Zou, S. HERRMANN & T. HAMAOKA. 1995. A sequence of cellular and molecular events involved in IL-12-induced tumor regression. Res. Jmmunol. 146: 636-644.
    • (1995) Res. Jmmunol. , vol.146 , pp. 636-644
    • Fujiwara, H.1    Zou, J.P.2    Herrmann, S.3    Hamaoka, T.4
  • 19
    • 0025808188 scopus 로고
    • Heterogeneous graft rejection pathways in class i major histocompatibility complexdisparate combinations and their differential susceptibility to immunomodulation induced by intravenous presensitization with relevant alloantigens
    • KlTAGAWA, S., H. IWATA, S. SATO, J. SHIMIZU, T. HAMAOKA & H. FUJIWARA. 1991. Heterogeneous graft rejection pathways in class I major histocompatibility complexdisparate combinations and their differential susceptibility to immunomodulation induced by intravenous presensitization with relevant alloantigens. J. Exp. Med. 174:571-581.
    • (1991) J. Exp. Med. , vol.174 , pp. 571-581
    • Kltagawa, S.1    Iwata, H.2    Sato, S.3    Shimizu, J.4    Hamaoka, T.5    Fujiwara, H.6
  • 22
    • 0022464285 scopus 로고
    • - T cell-mediated tumor-eradicating mechanism in vivo
    • - T cell-mediated tumor-eradicating mechanism in vivo. BioEssays 4: 19-23.
    • (1986) BioEssays , vol.4 , pp. 19-23
    • Fujiwara, H.1    Hamaoka, T.2
  • 24
    • 0024384319 scopus 로고
    • IL-2 and IFN-γ are two necessary lymphokines in the development of cytotoxic T-cells
    • MARASKOVSKY, E., W. F. CHEN & K. SHORTMAN. 1989. IL-2 and IFN-γ are two necessary lymphokines in the development of cytotoxic T-cells. J. Immunol. 143: 1210-1214.
    • (1989) J. Immunol. , vol.143 , pp. 1210-1214
    • Maraskovsky, E.1    Chen, W.F.2    Shortman, K.3
  • 28
    • 0026629902 scopus 로고
    • Nitric oxide as a secretory product of mammalian cells
    • NATHAN, C. 1992. Nitric oxide as a secretory product of mammalian cells. FASEB J. 6: 3051-3064.
    • (1992) FASEB J. , vol.6 , pp. 3051-3064
    • Nathan, C.1
  • 29
    • 0026034432 scopus 로고
    • Role of nitric oxide synthesis in macrophage antimicrobial activity
    • NATHAN, C. F. & J. B. HIBBS, JR. 1991. Role of nitric oxide synthesis in macrophage antimicrobial activity. Curr. Opin. Immunol. 3: 65-70.
    • (1991) Curr. Opin. Immunol. , vol.3 , pp. 65-70
    • Nathan, C.F.1    Hibbs Jr., J.B.2
  • 30
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology and pharmacology
    • MONCADA, S., R. M. J. PALMER & E. A. HIGGS. 1991. Nitric oxide: Physiology, pathophysiology and pharmacology. Pharmacol. Rev. 43: 109-142.
    • (1991) Pharmacol. Rev. , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.J.2    Higgs, E.A.3
  • 31
    • 0017741071 scopus 로고
    • Macrophage tumor killing: Influence of the local environment
    • HIBBS, J. B., R. R. TAINTOR, H. A. CHAPMAN & J. B. WEINBERG. 1977. Macrophage tumor killing: Influence of the local environment. Science 197: 279-282.
    • (1977) Science , vol.197 , pp. 279-282
    • Hibbs, J.B.1    Taintor, R.R.2    Chapman, H.A.3    Weinberg, J.B.4
  • 32
    • 0024584020 scopus 로고
    • Nitric oxide: A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells
    • STUEHR, D. J. & C. F. NATHAN. 1989. Nitric oxide: A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells. J. Exp. Med. 169: 1543-1555.
    • (1989) J. Exp. Med. , vol.169 , pp. 1543-1555
    • Stuehr, D.J.1    Nathan, C.F.2
  • 33
    • 0023706894 scopus 로고
    • Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production
    • DING, A. H., C. F. NATHAN & D. J. STUEHR. 1988. Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production. J. Immunol. 141: 2407-2412.
    • (1988) J. Immunol. , vol.141 , pp. 2407-2412
    • Ding, A.H.1    Nathan, C.F.2    Stuehr, D.J.3
  • 35
    • 0028102802 scopus 로고
    • Constitutive and inducible nitric oxide synthase gene expression, regulation, and activity in human lung epithelial cells
    • ASANO, K., C. B. E. CHEE, B. GASTON, C. M. LILLY, C. GERARD, J. M. DRAZEN & J. S. STAMLER. 1994. Constitutive and inducible nitric oxide synthase gene expression, regulation, and activity in human lung epithelial cells. Proc. Natl. Acad. Sci. USA 91: 10089-10093.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 10089-10093
    • Asano, K.1    Chee, C.B.E.2    Gaston, B.3    Lilly, C.M.4    Gerard, C.5    Drazen, J.M.6    Stamler, J.S.7
  • 36
    • 0018148373 scopus 로고
    • Indoleamine 2,3dioxygenase. Purification and some properties
    • SHIMIZU, T., S. NOMIYAMA, F. HIRATA & O. HAYAISHI. 1978. Indoleamine 2,3dioxygenase. Purification and some properties. J. Biol. Chem. 253: 4700-4706.
    • (1978) J. Biol. Chem. , vol.253 , pp. 4700-4706
    • Shimizu, T.1    Nomiyama, S.2    Hirata, F.3    Hayaishi, O.4
  • 38
    • 0040858936 scopus 로고
    • Induction of indoleamine 2,3dioxygenase: A mechanism of the antitumor activity of interferon-y
    • OZAKI, Y., M. P. EDELSTEIN & D. S. DUCH. 1988. Induction of indoleamine 2,3dioxygenase: A mechanism of the antitumor activity of interferon-y. Proc. Natl. Acad. Sci. USA 85: 1242-1246.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 1242-1246
    • Ozaki, Y.1    Edelstein, M.P.2    Duch, D.S.3
  • 39
    • 0028967644 scopus 로고
    • The role of indoleamine 2,3-dioxygenase in the anti-tumor activity of human interferon-y in vivo
    • BURKE, F., R. G. KNOWLES, N. EAST & F. R. BALKWILL. 1995. The role of indoleamine 2,3-dioxygenase in the anti-tumor activity of human interferon-y in vivo. Intl. J. Cancer 60: 115-122. t
    • (1995) Intl. J. Cancer , vol.60 , pp. 115-122
    • Burke, F.1    Knowles, R.G.2    East, N.3    Balkwill, F.R.4
  • 40
    • 0027994349 scopus 로고
    • The sphingomyelin cycle and the second messenger function of ceramide
    • HANNUN, Y. A. 1994. The sphingomyelin cycle and the second messenger function of ceramide. J. Biol. Chem. 269: 3125-3128.
    • (1994) J. Biol. Chem. , vol.269 , pp. 3125-3128
    • Hannun, Y.A.1
  • 41
    • 0028339322 scopus 로고
    • Cell-permeable ceramides inhibit the stimulation of DNA synthesis and phospholipase D activity by phosphatidate and lysophosphatidate in rat fibroblasts
    • GOMEZ-MUNOZ, A., A. MARTIN, L. O'BRIEN & D. N. BRINDLEY. 1994. Cell-permeable ceramides inhibit the stimulation of DNA synthesis and phospholipase D activity by phosphatidate and lysophosphatidate in rat fibroblasts. J. Biol. Chem. 269: 8937-8943.
    • (1994) J. Biol. Chem. , vol.269 , pp. 8937-8943
    • Gomez-Munoz, A.1    Martin, A.2    O'Brien, L.3    Brindley, D.N.4
  • 43
    • 0026007737 scopus 로고
    • Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor a and y-interferon: Specific role in cell differentiation
    • KIM, M. Y., C. LINARDIC, L. OBEID & Y. HANNUN. 1991. Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor a and y-interferon: Specific role in cell differentiation. J. Biol. Chem. 266: 484-489.
    • (1991) J. Biol. Chem. , vol.266 , pp. 484-489
    • Kim, M.Y.1    Linardic, C.2    Obeid, L.3    Hannun, Y.4
  • 45
    • 0027461121 scopus 로고
    • Activation of the sphingomyelin pathway in intact EL4 cells and in a cell-free system by IL-1/3
    • MATHIAS, S., A. YOUNES, C. C. KAN, I. ORLOW, C. JOSEPH & R. N. KOLESNICK. 1993. Activation of the sphingomyelin pathway in intact EL4 cells and in a cell-free system by IL-1/3. Science (Washington, DC) 259: 519-522.
    • (1993) Science (Washington, DC) , vol.259 , pp. 519-522
    • Mathias, S.1    Younes, A.2    Kan, C.C.3    Orlow, I.4    Joseph, C.5    Kolesnick, R.N.6
  • 46
    • 0019929408 scopus 로고
    • Preferential effect of interferon-y on the synthesis of HLA antigens and their mRNAs in human cells
    • WALLACH, D., M. FELLOUS & M. REVEL. 1982. Preferential effect of interferon-y on the synthesis of HLA antigens and their mRNAs in human cells. Nature 299:833-836.
    • (1982) Nature , vol.299 , pp. 833-836
    • Wallach, D.1    Fellous, M.2    Revel, M.3
  • 47
    • 0026012869 scopus 로고
    • IFN-y induces the expression of the genes for MHC class II I-A/3 and tumor necrosis factor through a protein kinase C-independent pathway
    • CELADA, A. & R. A. MAKI. 1991. IFN-y induces the expression of the genes for MHC class II I-A/3 and tumor necrosis factor through a protein kinase C-independent pathway. J. Immunol. 146: 114-120.
    • (1991) J. Immunol. , vol.146 , pp. 114-120
    • Celada, A.1    Maki, R.A.2


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