Random sequence phosphorothioate oligonucleotides evoke dramatic phenotypic alterations in cardiac myocyte cultures

Antisense and Nucleic Acid Drug Development

Volumn 6, Issue 4, 1996, Pages 259-265

  Davis, Dorene L ^a   Doten, Ian C ^b   Barald, Kate F ^b   Axelrod, Daniel ^c   Burch, John B E ^a  

^a FOX CHASE CANCER CENTER   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATRIAL NATRIURETIC FACTOR; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE;

ANIMAL CELL; ARTICLE; BLEACHING; CELL JUNCTION; CELL STRUCTURE; CONTROLLED STUDY; DNA SEQUENCE; GENE EXPRESSION REGULATION; HEART CELL CULTURE; HEART MUSCLE CONTRACTILITY; NONHUMAN; PRIORITY JOURNAL;

EID: 0030472815     PISSN: 10872906     EISSN: None     Source Type: Journal    
DOI: 10.1089/oli.1.1996.6.259     Document Type: Article

References (7)

1. AGRAWAL, S., GOODCHILD, J., CIVEIRA, M.P., TRONTON, A.M., SARIN, P.S., and ZAMECNIK, P.C. (1988). Oligodeoxynucleotide phosphoramidates and phosphorothioates as inhibitors of human immunodeficiency virus. Proc. Natl. Acad. Sc. USA 85, 7079-7083.
2. AKIZUKI, N., KANGAWA, K., MINAMINO, N., and MATSUO, H. (1991). Cloning and sequence analysis of complementary DNA encoding a precursor for chicken natriuretic peptide. FEBS Lett. 280, 357-362.
3. 1-adrenergic receptor signaling in cardiac cells. EMBO J. 12, 5131-5139.
4. BEYER, E.C. (1993). Gap junctions. Int. Rev. Cytol. 137, 1-37.
5. FORNWALD, J.A., KUNCIO, G., PENG, I., and ORDAHL, C.P. (1982). The complete nucleotide sequence of chick α-actin gene and its evolutionary relationship to the actin gene family. Nucleic Acids Res. 10, 3861-3876.
6. GONZALEZ-SANCHEZ, A., and BADER, D. (1984). Immunochemical analysis of myosin heavy chains in the developing chick heart. Dev. Biol. 103, 151-158.
7. ZADEH, B.J., GONZALEZ-SANCHEZ, A., FISHMAN, D.A., and BADER, D.M. (1986). Myosin heavy chain expression in embryonic cardiac cell cultures. Dev. Biol. 115, 204-214.