Diclofenac-induced immune haemolytic anaemia: Simultaneous occurrence of red blood cell autoantibodies and drug-dependent antibodies

British Journal of Haematology

Volumn 95, Issue 4, 1996, Pages 640-644

  Salama, Abdulgabar ^a   Kroll, Hartmut ^b   Wittmann, Georg ^a   Mueller Eckhardt, Christian ^b  

^a HUMBOLDT UNIVERSITY   (Germany)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

autoantibodies; drug dependent antibodies; drug induced; immune haemolysis

Indexed keywords

AUTOANTIBODY; DICLOFENAC; DRUG ANTIBODY; ERYTHROCYTE ANTIBODY; NEOANTIGEN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; AUTOIMMUNITY; CLINICAL ARTICLE; ETIOLOGY; FEMALE; HEMOLYTIC ANEMIA; HUMAN; INTRAMUSCULAR DRUG ADMINISTRATION; MALE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SIDE EFFECT;

EID: 0030472499     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1996.d01-1947.x     Document Type: Article

References (16)

1. Angeles, M.L., Reid, M.E., Yacob, U.A., Cash, K.L. & Fetten, J.V. (1994) Sulindac-induced immune hemolytic anemia. Transfusion, 34, 255-258.
2. Branch, D.R., Sy Siok Hian, A.L. & Petz, L.D. (1982) A new elution procedure using chloroform, a non flammable organic solvent. Vox Sanguinis, 42, 46-53.
3. Chan-Lam, D., Thorburn, A.W., Chalmers, E.A., Watson, W.H. & Fitzsimons, E.J. (1986) Red cell antibodies and autoimmune haemolysis after treatment with azapropazone. British Medical Journal, 293, 1474.
4. Ciucci, A.G. (1980) A review of spontaneously reported adverse drug reactions with diclofenac sodium (Voltarol). Rheumatology and Rehabilitation, 18, 116-121.
5. Garratty, G. (1993) Drug-induced immune hemolytic anemia. Immunobiology of Transfusion Medicine (ed. by G. Garratty), pp. 523-551. Dekker, New York.
6. Habibi, B. (1985) Drug induced red blood cell autoantibodies co-developed with drug specific antibodies causing haemolytic anaemias. British Journal of Haematology, 61, 139-143.
7. Kramer, M.R., Levene, C. & Hershko, C. (1986) Severe reversible autoimmune haemolytic anaemia and thrombocytopenia associated with diclofenac therapy. Scandinavian Journal of Haematology, 36, 118-120.
8. Mueller-Eckhardt, C. & Salama, A. (1990) Drug-induced immune cytopenias: a unifying pathogenetic concept with special emphasis on the role of drug metabolites. Transfusion Medicine Reviews, 4, 469-477.
9. Petz, L.D. (1993) Drug-induced autoimmune hemolytic anemia. Transfusion Medicine Reviews, 7, 242-254.
10. Petz, L.D. & Garratty, G. (1980) Acquired Immune Hemolytic Anemias. Churchill Livingstone, New York.
11. Salama, A., Berghöfer, H. & Mueller-Eckhardt, C. (1992) Detection of cell-drug (hapten)-antibody complexes by the gel test. Transfusion, 32, 554-556.
12. Salama, A., Göttsche, B. & Mueller-Eckhardt, C. (1991) Autoantibodies and drug- or metabolite-dependent antibodies in patients with diclofenac-induced immune haemolysis. British Journal of Haematology, 77, 546-549.
13. Salama, A. & Mueller-Eckhardt, C. (1985) The role of metabolite-specific antibodies in nomifensine-dependent immune hemolytic anemia. New England Journal of Medicine, 313, 469-474.
14. Sanford-Driscoll, M. & Knodel, L.C. (1986) Induction of hemolytic anemia by nonsteroidal antiinflammatory drugs. Drug Intelligence in Clinical Pharmacology, 20, 925-934.
15. Van Dijk, B.A., Barrera Rico, P., Hoitsma, A. & Kunst, V.A.J.M. (1989) Immune hemolytic anemia associated with tolmetin and suprofen. Transfusion, 29, 638-641.
16. Worlledge, S.M. (1975) Immune drug-induced hemolytic anemias. Seminars in Hematology, 10, 327-344.