Increased expression of neutrophil mrp8 and mrp14 is associated with vascular adhesion molecule activation and differential leukocyte infiltration in delayed-type hypersensitivity suggesting a proinflammatory role for s100 calcium-binding proteins

International Journal of Immunopathology and Pharmacology

Volumn 9, Issue 3, 1996, Pages 79-94

  Dunn, C J ^a   Chosay, J G ^a   Essani, N A ^a   Cruz, R ^a   Manning, A M ^b   Galinet, L A ^a   Eversole, R R ^c   Yem, A W ^a   Deibel, M R ^a  

^a PFIZER INC   (United States)

^b Signal Pharmaceuticals   (United States)

^c WESTERN MICHIGAN UNIVERSITY   (United States)

Author keywords

Chemotaxis; MRP14; MRP8; Neutrophil; Proinflammatory; S100 calcium binding proteins

Indexed keywords

ANTIGEN; BETA1 INTEGRIN; BOVINE SERUM ALBUMIN; CD4 ANTIGEN; CD8 ANTIGEN; CELL ADHESION MOLECULE; INTERCELLULAR ADHESION MOLECULE 1; MESSENGER RNA; METHYLATED ALBUMIN; MIGRATION INHIBITION FACTOR RELATED PROTEIN 14; MIGRATION INHIBITION FACTOR RELATED PROTEIN 8; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; CELL INFILTRATION; CELLULAR DISTRIBUTION; CHEMOTAXIS; CONTROLLED STUDY; CYTOPLASM; DELAYED HYPERSENSITIVITY; ELECTRON MICROSCOPY; FIBROBLAST; MACROPHAGE; MONOCYTE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; SENSITIZATION; SKIN INFLAMMATION; T LYMPHOCYTE;

EID: 0030471683     PISSN: 03946320     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Kligman, D. and D. C. Hilt. 1988. The S100 protein family. Trends Biochem. Sci. 13:437.
2. 2+-binding proteins of neutrophils and monocytes. J. Leukocyte Biol. 53:197.
3. Wilkinson, M. M., A. Busuttil, C. Hayward, D. J. H. Brock, J. R. Dorin, and V. Van Heyningen. 1988. Expression pattern of two related cystic fibrosis-associated calcium-binding proteins in normal and abnormal tissues. J. Cell Sci. 91:221.
4. Zwadlo, G., R. Schlegel, and C. Sorg. 1986. A monoclonal antibody to a subset of human monocytes found only in the peripheral blood and inflammatory tissues. J. Immunol. 137:512.
5. Odink, K., N. Cerletti, J. Brüggen, R. G. Clerc, L. Tarcsay, G. Zwadlo, G. Gerhards, R. Schlegel, and C. Sorg. 1987. Two calcium-binding proteins in infiltrate macrophages of rheumatoid arthritis. Nature 330:80.
6. Delabie, J., C. De Wolf-Peeters, J. J. Van Den Oord, and V. J. Desmet. 1990. Differential expression of the calcium-binding proteins MRP8 and MRP14 in granulomatous conditions: an immunohistochemical study. Clin. Exp. Immunol. 81:123.
7. Stockley, R. A., I. Dale, S. L. Hill, and M. K. Fagerhol. 1984. Relationship of neutrophil cytoplasmic protein (L1) to acute and chronic lung disease. Scand. J. Clin. Labs. Invest. 44:629.
8. Brun, J.G., R. Jonsson, and H. Haga. 1994. Measurement of plasma calprotectin as an indicator of arthritis and disease activity in patients with inflammatory rheumatic diseases. J. Rheumatol. 21:733.
9. Hogg, N., C. Allen, and J. Edgeworth. 1989. Monoclonal antibody 5.5 reacts with p8,14, a myeloid molecule associated with some vascular endothelium. Eur. J. Immunol. 199:1053.
10. Lagasse, E. and I. L. Weissman. 1992. Mouse MRP8 and MRP14, two intracellular calcium-binding proteins associated with the development of the myeloid lineage. Blood 79:1907.
11. Lackmann, M., C. J. Cornish, R. J. Simpson, R. L. Moritz, and C. L. Geczy. 1992. Purification and structural analysis of a murine chemotactic cytokine (CP-10) with sequence homology to S100 proteins. J. Biol. Chem. 267:7499.
12. Lackmann, M., P. Rajasekariah, S. E. Iismaa, G. Jones, C. J. Cornish, S. Hu, R. J. Simpson, R. L. Moritz, and C. L. Geczy. 1993. Identification of a chemotactic domain of the pro-inflammatory S100 protein CP-10. J. Immunol. 150:2981.
13. Devery, J. M., N. J. C. King, and C. L. Geczy. 1994. Acute Inflammatory Activity of the S100 Protein CP-10; Activation of Neutrophils in vivo and in vitro. J. Immunol. 152:1888.
14. Mariggió, M. A., S. Fulle, P. Calissano, I. Nicoletti, and G. Fanó. 1994. The brain protein S-100ab induces apoptosis in PC12 cells. Neuroscience 60:29.
15. Mori, S., K. Goto, F. Goto, K. Murakami, S. Ohkawara, and M. Yoshinaga. 1994. Dynamic changes in mRNA expression of neutrophils during the course of acute inflammation in rabbits. Int. Immunol. 6:149.
16. Engvall, E. and P. Perlmann. 1971. Enzyme-linked immunoabsorbent assay (ELISA). Quantitative assay of immunoglobulin G. Immunochem. 8:871.
17. Dunn, C. J., L. A. Galinet, H. Wu, R. A. Nugent, S. T. Schlachter, N. D. Staite, D. G. Aspar, G. A. Elliott, N. A. Essani, N. A. Rohloff and R. J. Smith. 1993. Demonstration of novel anti-arthritic and anti-inflammatory effects of diphosphonates. J. Pharma. Exper. Therapeutics 266:1691.
18. Bell, F. P. and C. J. Dunn. 1990. Lipid Metabolism in the inflammatory lesion of a mouse model of delayed type hypersensitivity. I. Increased AcylCoA:Cholesterol Acyltransferase activity as an integral component of the inflammatory response. Exp. Mol. Pathol. 55:160.
19. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680.
20. Chomezynski, P. and N. Sacchi. 1987. Single step method of RNA isolation by acid guanidinium thiocynate-phenol-chloroform extraction. Anal. Biochem. 162:156.
21. Maniatis, T., E. F. Fritsch and J. Sambrook. 1989. Molecular Cloning: A Laboratory Manual. (Abstract)
22. 4-integrins. J. Mol. Med. 73:347.
23. Silber, A., W. Newman, K. A. Reimann, E. Hendricks, D. Walsh and D. J. Ringler. 1994. Kinetic expression of endothelial adhesion molecules and relationship to leukocyte recruitment in two cutaneous models of inflammation. Lab. Invest. 70:163.
24. Roth, J., C. Sunderkötter, M. Goebeler, J. Gutwald and C. Sorg. 1992. Expression of the calcium-binding proteins MRP8 and MRP14 by early infiltrating cells in experimental contact dermatitis. Int. Arch. Allergy Immunol. 95:140.
25. Murao, S., F. Collart and E. Huberman. 1990. A protein complex expressed during terminal differentiation of monomyelocytic cells is an inhibitor of cell growth. Cell Growth Differentiation 1:447.