Suppressive action of endogenous adenosine on ovine fetal nonshivering thermogenesis

Journal of Applied Physiology

Volumn 81, Issue 6, 1996, Pages 2393-2398

  Ball, Karen T ^b   Gunn, Tania R ^b   Gluckman, Peter D ^b   Power, Gordon G ^a  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

A1 receptor antagonist; brown adipose tissue; placenta

Indexed keywords

ADENOSINE; ADENOSINE RECEPTOR; ADENOSINE RECEPTOR BLOCKING AGENT; FATTY ACID; GLUCOSE; GLYCEROL; OXYGEN; THEOPHYLLINE;

ANIMAL EXPERIMENT; ARTICLE; BIRTH; BROWN ADIPOSE TISSUE; COLD EXPOSURE; CONTROLLED STUDY; FETUS; NONHUMAN; PLACENTA; PRIORITY JOURNAL; SHEEP; SIMULATION; THERMOGENESIS; UMBILICAL CORD;

EID: 0030471542     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1996.81.6.2393     Document Type: Article

References (29)

1. Alexander, G., D. Nicol, and G. Thorburn. Thermogenesis in prematurely delivered lambs. In: Fetal and Neonatal Physiology. Proc. of the Sir Joseph Barcroft Centenary Symp., edited by K. S. Comline, K. W. Cross, and G. S. Dawes. Cambridge, UK: Cambridge Univ. Press, 1973, p. 410-417.
2. Alexander, G., and D. Stevens. Sympathetic innervation and the development of structure and function of brown adipose tissue: studies on lambs chemically sympathectomized in utero with 6-hydroxydopamine. J. Dev. Physiol. 2: 119-137, 1980.
3. Arnold, S. T., and R. L. Cysyk. Adenosine export from the liver: oxygen dependency. Am. J. Physiol. 251 (Gastrointest. Liver Physiol. 14): G34-G39, 1986.
4. Ball, K. T., T. R. Gunn, G. G. Power, H. Asakura, and P. D. Gluckman. A potential role for adenosine in the inhibition of nonshivering thermogenesis in the fetal sheep. Pediatr. Res. 37: 303-309, 1995.
5. Belle, H. van. Uptake and deamination of adenosine by blood. Species differences, effect of pH, ions, temperature and metabolic inhibitors. Biochim. Biophys. Acta 192: 124-132, 1969.
6. Falholt, K., B. Lund, and W. Falholt. An easy colorimetric micromethod for routine determination of free fatty acids in plasma. Clin. Chim. Acta 46: 105-111, 1973.
7. Fredholm, B., and P. Hedqvist. Modulation of neurotransmission by purine nucleotides and nucleosides. Biochem. Pharmacol. 29: 1635-1643, 1980.
8. Fredholm, B., and A. Sollevi. Regulation of lipolysis and circulation in adipose tissue. In: Purines: Pharmacology and Physiological Roles, edited by T. W. Stone. London: Macmillan, 1985, p. 223-232.
9. Gunn, T. R., K. T. Ball, G. G. Power, and P. D. Gluckman. Withdrawal of placental prostaglandins permits thermogenic responses in fetal sheep brown adipose tissue. J. Appl. Physiol. 74: 998-1004, 1993.
10. Higbee, M. D., M. Kumar, and S. P. Galant. Stimulation of endogenous catecholamme release by theophylline: a proposed additional mechanism of action for theophylline effects. J. Allergy Clin. Immunol. 70: 377-382, 1982.
11. Hodgkin, D., R. D. Gilbert, and G. G. Power. In vivo brown fat response to hypothermia and norepinephrine in the ovine fetus. J. Dev. Physiol. 10: 383-391, 1988.
12. Klein, A. H., A. Reviczky, P. Chou, J. Padbury, and D. A. Fisher. Development of brown adipose tissue thermogenesis in the ovine fetus and newborn. Endocrinology 112: 1662-1666, 1983.
13. Mitchell, M. D., and A. P. F. Flint. Prostaglandin production by intra-uterine tissues from periparturient sheep: use of a superfusion technique. J. Endocrinol. 76: 111-121, 1978.
14. Newby, A. C., Y. Worku, P. Meghji, M. Nakazawa, and A. Skladanowski. Adenosine: a retaliatory metabolite or not? News Physiol. Sci. 5: 67-70, 1990.
15. Pinter, J. K., J. A. Hayashi, J. A. Watson. Enzymatic assay of glycerol, dehydroxyacetone, and glyceraldehyde. Arch. Biochem. Biophys. 121: 404-414, 1967.
16. Power, G. G., T. R. Gunn, B. M. Johnston, and P. D. Gluckman. Oxygen supply and the placenta limit thermogenic responses in fetal sheep. J. Appl. Physiol. 63: 1896-1901, 1987.
17. 3 or norepinephrine stimulate brown adipose tissue thermogenesis in the fetal sheep. J. Dev. Physiol. 11: 171-177, 1989.
18. Rall, T. W. Evolution of the mechanism of action of methylxanthines: from calcium mobilizes to antagonists of adenosine receptors. Pharmacology 24: 277-287, 1982.
19. Sawa, R., H. Asakura, and G. G. Power. Changes in plasma adenosine during simulated birth of fetal sheep. J. Appl. Physiol. 70: 1524-1528, 1991.
20. 1-adrenergic agonists in regulation of respiration in hamster brown adipocytes. Mol. Pharmacol. 32: 26-33, 1987.
21. Schimmel, R. J., and L. McCarthy. Effects of insulin, adenosine, and prostaglandin on α-adrenergic-stimulated respiration in brown adipocytes. Am. J. Physiol. 250 (Cell Physiol. 19): C738-C743, 1986.
22. Schimmel, R. J., L. McCarthy, and D. Dzierzanowski. Effects of pertussis toxin treatment on metabolism in hamster brown adipocytes. Am. J. Physiol. 249 (Cell Physiol. 18): C456-C463, 1985.
23. 1-Adrenergic stimulation of hamster brown adipocyte respiration. Am. J. Physiol. 244 (Cell Physiol. 13): C362-C368, 1983.
24. Siegel, P., H. Kitagawa, and M. H. Maguire. Determination of adenosine in fetal perfusates of human placental cotyledons using fluorescence derivatization and reversed-phase high-performance liquid chromatography. Anal. Biochem. 171: 124-134, 1988.
25. Steinberg, D., M. Vaughan, P. J. Nestel, O. Strand, and S. Bergstrom. Effects of the prostaglandins on hormone-induced mobilization of free fatty acids. J. Clin. Invest. 43: 1533-1540, 1964.
26. Swinyard, E. A. Respiratory drugs. In: Remington's Pharmaceutical Sciences, edited by A. Osol. Easton, PA: Mack, 1980, p. 809-814.
27. Szillat, D., and L. Bukowiecki. Control of brown adipose tissue lipolysis and respiration by adenosine. Am. J. Physiol. 245 (Endocrinol. Metab. 8): E555-E559, 1983.
28. Wang, L. C. H., S. F. P. Man, and A. N. Belcastro. Metabolic and hormonal responses in theophylline-increased cold resistance in males. J. Appl. Physiol. 63: 589-596, 1987.
29. 6-phenylisopropyladenosine and hypothyroidism on the responsiveness of rat brown adipocytes to norepinephrine. Biochem. J. 238: 395-403, 1986.