Levels of estrogen receptor immunoreactivity are altered in behaviorally-relevant brain regions in female rats during pregnancy

Molecular Brain Research

Volumn 42, Issue 2, 1996, Pages 328-336

  Wagner, Christine K ^a   Morrell, Joan I ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

Bed nucleus of the stria terminalis; Maternal behavior; Medial amygdala; Medial preoptic nucleus; Postpartum; Steriod receptor; Ventromedial nucleus

Indexed keywords

ESTROGEN RECEPTOR;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DELIVERY; FEMALE; IMMUNOCYTOCHEMISTRY; IMMUNOREACTIVITY; MATERNAL BEHAVIOR; NONHUMAN; PREGNANCY; PREOPTIC NUCLEUS; PRIORITY JOURNAL; RAT; SEXUAL BEHAVIOR; THALAMUS VENTRAL NUCLEUS;

ANIMALS; BRAIN; FEMALE; LABOR, OBSTETRIC; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ESTROGEN; SEXUAL BEHAVIOR, ANIMAL;

EID: 0030471047     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(96)00141-6     Document Type: Article

References (30)

1. [1] Adieh, H.B., Mayer, A.D. and Rosenblatt, J.S., Effects of brain antiestrogen implants on maternal behavior and on postpartum estrus in pregnant rats, Neuroendocrinology, 46 (1987) 522-531.
2. [2] Blaustein, J.D., Cytoplasmic estrogen receptors in rat brain: Immunocytochemical evidence using three antibodies with distinct epitopes, Endocrinology, 131 (1992) 1336-1342.
3. [3] Conner, J.R. and Davis, H.N., Postpartum estrus in Norway rats. I. Behavior, Biol. Reprod., 23 (1980) 994-999.
4. [4] Fahrbach, S.E. and Pfaff, D.W., Effects of preoptic area implants of dilute estradiol on the maternal behavior of ovariectomized, nulliparous rats, Horm. Behav., 20 (1986) 354-363.
5. [5] Friend, K.E., Ang, L.W. and Shupnik, M.A., Estrogen regulates the expression of several different estrogen receptor isoforms in rat pituitary, Proc. Natl. Acad. Sci. USA, 92 (1995) 4367-4371.
6. [6] Giordano, A.L., Siegel, H.I. and Rosenblatt, J.S., Nuclear estrogen receptor binding in microdissected brain regions of female rats during pregnancy: Implications for maternal and sexual behavior, Physiol. Behav., 50 (1991) 1263-1267.
7. [7] Giordano, A.L., Ahdieh, H.B., Mayer, A.D., Siegel, H.I. and Rosenblatt, J.S., Cytosol and nuclear estrogen receptor binding in the preoptic area and hypothalamus of female rats during pregnancy and ovariectomized, nulliparous rats after steroid priming: correlation with maternal behavior, Horm. Behav., 24 (1990) 232-255.
8. [8] Gray, P. and Brooks, P.J., Effect of lesion location within the medial preoptic-anterior hypothalamic continuum on maternal and male sexual behaviors in female rats, Behav. Neurosci., 98 (1984) 703-711.
9. [9] Jacobson, C.D., Terkel, J., Gorski, R.A. and Sawyer, C.H., Effects of small medial preoptic area lesions on maternal behavior: retrieving and nest building in the rat, Brain Res., 194 (1980) 471-478.
10. [10] Keppel, G., Design and Analysis: A Researcher's Handbook, Prentice-Hall, Englewood Cliffs, NJ, 1982, 151 pp.
11. [11] Koch, M. and Ehret, G., Immunocytochemical localization and quantitation of estrogen-binding cells in the male and female (virgin, pregnant, lactating) mouse brain, Brain Res., 489 (1989) 101-112.
12. [12] Mayer, A.D. and Rosenblatt, J.S., Hormonal interaction with stimulus and situational factors in the initiation of maternal behavior in nonpregnant rats, J. Comp. Physiol. Psychol., 94 (1980) 1040-1059.
13. [13] Miceli, M.O., Fleming, A.S. and Malsbury, C.W., Disruption of maternal behavior in virgin and postparturient rats following sagittal plane knife cuts in the preoptic area-hypothalamus, Behav. Brain Res., 9 (1983) 337-360.
14. [14] Miggliaccio, A., Rotundi, A. and Auricchio, F., Calmodulin-stimulated phosphorylation of 17B-estradiol receptor on tyrosine, Proc. Natl. Acad. Sci. USA, 81 (1984) 5921-5925.
15. [15] Norstedt, G., Wrange, O. and Gustafsson, J.-A., Multihormonal regulation of the estrogen receptor in rat liver, Endocrinology, 108 (1981) 1190-1196.
16. [16] Numan, M., 1974 Medial preoptic area and maternal behavior in the rat, J. Comp. Physiol. Psychol., 87 (1986) 746-759.
17. [17] Numan, M., Maternal behavior. In E. Knobil and J.D. Neill (Eds.), The Physiology of Reproduction, Raven Press, New York, 1994, pp. 221-302.
18. [18] Numan, M., Numan, M.J. and English, J.B., Excitotoxic amino acid injections into the medial amygdala facilitate maternal behavior in virgin female rats, Horm. Behav., 27 (1993) 56-81.
19. [19] Numan, M., Rosenblatt, J.S. and Komisaruk, B.R., Medial preoptic area and onset of maternal behavior in the rat, J. Comp. Physiol. Psychol., 91 (1977) 146-164.
20. [20] Pfaff, D.W. and Schwartz-Giblin, S., Cellular mechanisms of female reproductive behaviors. In E. Knobil and J.D. Neill (Eds.), The Physiology of Reproduction, Raven Press, New York, 1994, pp. 1487-1568.
21. [21] Sanyal, M.K.J., Secretion of progesterone during gestation in the rat, Endocrinology, 79 (1978) 179-190.
22. [22] Sarff, M. and Gorski, J., Control of estrogen binding protein concentration under basal conditions and after estrogen administration, Biochemistry, 10 (1971) 2557-2563.
23. [23] Shaikh, A.A., Estrone and estradiol levels in the ovarian venous blood from rats during the estrous cycle and pregnancy, Biol. Reprod., 5 (1971) 297-307.
24. [24] Shughrue, P.J., Bushnell, CD. and Dorsa, D.M., Estrogen receptor messenger ribonucleic acid in female rat brain during the estrous cycle: a comparison with ovariectomized females and intact males, Endocrinology, 131 (1992) 381-388.
25. [25] Shupnik, M.A., Gordon, M.S. and Chin, W.W., Tissue-specific regulation of rat estrogen receptor mRNAs, Mol. Endocrinol., 3 (1989) 660-665.
26. [26] Singh, P. and Muldoon, T.G., Baseline and luteinizing hormone-releasing hormone-perturbed patterns of estrogen receptor distribution in anterior pituitary cell nuclei, Endocrinology, 118 (1986) 2355-2361.
27. [27] Skipper, J.K., Young, L.J., Bergeron, J.M., Tetzlaff, M.T., Osborn, C.T. and Crews, D., Identification of an isoform of the estrogen receptor messenger RNA lacking exon four and present in brain, Proc. Natl. Acad. Sci. USA, 90 (1993) 7172-7175.
28. [28] Terkel, J., Bridges, R.S. and Sawyer, C.H., Effects of transecting lateral neural connections of the medial preoptic area on maternal behavior in the rat: nest building, pup retrieval and prolactin secretion, Brain Res., 169 (1979) 369-380.
29. [29] Wagner, C.K. and Morrell, J.I., In situ analysis of estrogen receptor mRNA expression in the brain of female rats during pregnancy, Mol. Brain Res., 33 (1995) 127-135.
30. [30] Zhou, Y., Shughrue, P.J. and Dorsa, D.M., Estrogen receptor protein is differentially regulated in the preoptic area of the brain and in the uterus during the rat estrous cycle, Neuroendocrinology, 61 (1995) 276-283.