-
1
-
-
0024400067
-
Methotrexate in Rheumatoid Arthritis: Toxic Effects as the Major Factor in Limiting Long-Term Treatment
-
Alarcón GS, Tracy IC, Blackburn WD Jr. Methotrexate in Rheumatoid Arthritis: Toxic Effects as the Major Factor in Limiting Long-Term Treatment. Arthritis Rheum 1989; 32: 671-6.
-
(1989)
Arthritis Rheum
, vol.32
, pp. 671-676
-
-
Alarcón, G.S.1
Tracy, I.C.2
Blackburn Jr., W.D.3
-
2
-
-
0025037994
-
The Effect of Folic Acid Supplementation on Toxicity of Low-Dose Methotrexate in Patients with Rheumatoid Arthritis
-
Morgan SL, Baggott JE, Vaughn WH, Young PK, Austin JV, Krumdieck CL, et al. The Effect of Folic Acid Supplementation on Toxicity of Low-Dose Methotrexate in Patients With Rheumatoid Arthritis. Arthritis Rheum 1990; 33: 9-18.
-
(1990)
Arthritis Rheum
, vol.33
, pp. 9-18
-
-
Morgan, S.L.1
Baggott, J.E.2
Vaughn, W.H.3
Young, P.K.4
Austin, J.V.5
Krumdieck, C.L.6
-
3
-
-
0028593942
-
Supplementation with Folic Acid during Methotrexate Therapy for Rheumatoid Arthritis. A Double-Blind Placebo Controlled Trial
-
Morgan SL, Baggott JE, Vaughn WH, Austin JS, Veitch TA, Lee JY, et al. Supplementation With Folic Acid During Methotrexate Therapy for Rheumatoid Arthritis. A Double-Blind Placebo Controlled Trial. Ann Intern Med 1994; 121: 833-41.
-
(1994)
Ann Intern Med
, vol.121
, pp. 833-841
-
-
Morgan, S.L.1
Baggott, J.E.2
Vaughn, W.H.3
Austin, J.S.4
Veitch, T.A.5
Lee, J.Y.6
-
4
-
-
0025887372
-
Exacerbation of Rheumatoid Arthritis in Patients Treated with Methotrexate after Administration of Folinic Acid
-
Joyce DA, Will RK, Hoffman DM, Laing B, Blackbourn SJ. Exacerbation of Rheumatoid Arthritis in Patients Treated With Methotrexate After Administration of Folinic Acid. Ann Rheum Dis 1991; 50: 913-4.
-
(1991)
Ann Rheum Dis
, vol.50
, pp. 913-914
-
-
Joyce, D.A.1
Will, R.K.2
Hoffman, D.M.3
Laing, B.4
Blackbourn, S.J.5
-
5
-
-
0023785897
-
The Effects of Leucovorin (Folinic Acid) on Methotrexate Therapy in Rheumatoid Arthritis Patients
-
Tishler M, Caspi D, Fishel B, Yaron M. The Effects of Leucovorin (Folinic Acid) on Methotrexate Therapy in Rheumatoid Arthritis Patients. Arthritis Rheum 1988; 31: 906-8.
-
(1988)
Arthritis Rheum
, vol.31
, pp. 906-908
-
-
Tishler, M.1
Caspi, D.2
Fishel, B.3
Yaron, M.4
-
6
-
-
0027285238
-
Low-Dose Methotrexate with Leucovorin (Folinic Acid) in the Management of Rheumatoid Arthritis. Results of a Randomized, Double-Blind, Placebo-Controlled Trial
-
Shiroky JB, Neville C, Esdaile JM, Choquette D, Zummer M, Hazeltine M, et al. Low-Dose Methotrexate With Leucovorin (Folinic Acid) in the Management of Rheumatoid Arthritis. Results of a Randomized, Double-Blind, Placebo-Controlled Trial. Arthritis Rheum 1993; 36: 795-803.
-
(1993)
Arthritis Rheum
, vol.36
, pp. 795-803
-
-
Shiroky, J.B.1
Neville, C.2
Esdaile, J.M.3
Choquette, D.4
Zummer, M.5
Hazeltine, M.6
-
7
-
-
0027160604
-
Low-Dose Leucovorin Does Not Interfere with the Efficacy of Methotrexate in Rheumatoid Arthritis: An 8 Week Randomized Placebo Controlled Trial
-
Weinblatt ME, Maier AL, Coblyn JS: Low-Dose Leucovorin Does Not Interfere With the Efficacy of Methotrexate in Rheumatoid Arthritis: An 8 Week Randomized Placebo Controlled Trial. J Rheumatol 1993; 20: 950-2.
-
(1993)
J Rheumatol
, vol.20
, pp. 950-952
-
-
Weinblatt, M.E.1
Maier, A.L.2
Coblyn, J.S.3
-
8
-
-
0024589484
-
Increasing Methotrexate Effect with Increasing Dose in the Treatment of Resistant Rheumatoid Arthritis
-
Furst DE, Koehnke R, Burnmeister LF, et al. Increasing Methotrexate Effect With Increasing Dose in the Treatment of Resistant Rheumatoid Arthritis. J Rheumatol 1989; 16: 313-20.
-
(1989)
J Rheumatol
, vol.16
, pp. 313-320
-
-
Furst, D.E.1
Koehnke, R.2
Burnmeister, L.F.3
-
9
-
-
0021923633
-
Efficacy of Low-Dose Methotrexate in Rheumatoid Arthritis
-
Weinblatt ME, Coblyn JS, Fox DA, Holdsworth DE, Glass DN, Trentham DE: Efficacy of Low-Dose Methotrexate in Rheumatoid Arthritis. N Engl J Med 1985; 312: 818-22.
-
(1985)
N Engl J Med
, vol.312
, pp. 818-822
-
-
Weinblatt, M.E.1
Coblyn, J.S.2
Fox, D.A.3
Holdsworth, D.E.4
Glass, D.N.5
Trentham, D.E.6
-
10
-
-
0021794435
-
Comparison of Low-Dose Oral Pulse Methotrexate and Placebo in the Treatment of Rheumatoid Arthritis: A Controlled Clinical Trial
-
Williams JH, Willkins RF, Samuelson Co Jr, Alarcon GS, Guttadauria M, Yarboro C, et al. Comparison of Low-Dose Oral Pulse Methotrexate and Placebo in the Treatment of Rheumatoid Arthritis: A Controlled Clinical Trial. Arthritis Rheum 1985; 28: 721-30.
-
(1985)
Arthritis Rheum
, vol.28
, pp. 721-730
-
-
Williams, J.H.1
Willkins, R.F.2
Samuelson Jr., Co.3
Alarcon, G.S.4
Guttadauria, M.5
Yarboro, C.6
-
11
-
-
0022137053
-
Weekly Pulse Methotrexate in Rheumatoid Arthritis: Clinical and Immunologic Effects in a Randomized, Double-Blind Study
-
Andersen PA, West SG, O'Dell JR, Via CS, Claypool RG, Kotzin BL. Weekly Pulse Methotrexate in Rheumatoid Arthritis: Clinical and Immunologic Effects in a Randomized, Double-Blind Study. Ann Intern Med 1985; 103: 489-96.
-
(1985)
Ann Intern Med
, vol.103
, pp. 489-496
-
-
Andersen, P.A.1
West, S.G.2
O'Dell, J.R.3
Via, C.S.4
Claypool, R.G.5
Kotzin, B.L.6
-
12
-
-
0025633939
-
Adverse Experience with Methotrexate during 176 Weeks of a Long-Term Prospective Trial in Patients with Rheumatoid Arthritis
-
Furst DE, Erikson N, Clute L, Koehnke R, Burmeister LF, Kohler JA: Adverse Experience With Methotrexate During 176 Weeks of a Long-Term Prospective Trial in Patients With Rheumatoid Arthritis. J Rheumatol 1990; 17: 1628-35.
-
(1990)
J Rheumatol
, vol.17
, pp. 1628-1635
-
-
Furst, D.E.1
Erikson, N.2
Clute, L.3
Koehnke, R.4
Burmeister, L.F.5
Kohler, J.A.6
-
13
-
-
0026537794
-
Long-Term Prospective Study of Methotrexate in the Treatment of Rheumatoid Arthritis: 84-Month Update
-
Weinblatt ME, Weissman BN, Holdsworth DE, Fraser PA, Maier AL, Falchuk KR, et al. Long-Term Prospective Study of Methotrexate in the Treatment of Rheumatoid Arthritis: 84-Month Update. Arthritis Rheum 1992; 35: 129-37.
-
(1992)
Arthritis Rheum
, vol.35
, pp. 129-137
-
-
Weinblatt, M.E.1
Weissman, B.N.2
Holdsworth, D.E.3
Fraser, P.A.4
Maier, A.L.5
Falchuk, K.R.6
-
14
-
-
0026548634
-
Long-Term Prospective Study of the Use of Methotrexate in the Treatment of Rheumatoid Arthritis: Update after a Mean of 90 Months
-
Kremer JM, Phelps CT. Long-Term Prospective Study of the Use of Methotrexate in the Treatment of Rheumatoid Arthritis: Update After a Mean of 90 Months. Arthritis Rheum 1992; 35: 138-45.
-
(1992)
Arthritis Rheum
, vol.35
, pp. 138-145
-
-
Kremer, J.M.1
Phelps, C.T.2
-
15
-
-
0017646050
-
Liver Biopsies from Psoriatics Related to Methotrexate Therapy: 3. Findings in Post-Methotrexate Liver Biopsies from 160 Psoriatics
-
Nyfors A. Liver Biopsies From Psoriatics Related to Methotrexate Therapy: 3. Findings in Post-Methotrexate Liver Biopsies From 160 Psoriatics. Acta Pathol Microbiol Scand [A] 1977; 85: 511-8.
-
(1977)
Acta Pathol Microbiol Scand [A]
, vol.85
, pp. 511-518
-
-
Nyfors, A.1
-
16
-
-
0018837419
-
Methotrexate Induced Liver Cirrhosis Studies Including Serial Liver Biopsies during Continued Treatment
-
Zachariae H, Kragballe K, Sogaard H. Methotrexate Induced Liver Cirrhosis Studies Including Serial Liver Biopsies During Continued Treatment. Brit J Dermatol 1980; 102: 407-12.
-
(1980)
Brit J Dermatol
, vol.102
, pp. 407-412
-
-
Zachariae, H.1
Kragballe, K.2
Sogaard, H.3
-
17
-
-
84948007868
-
Psoriasis-Liver-Methotrexate Interactions
-
Weinstein GD, Reonigk H, Maibach HI, Weinstein G, Cosmides J, Halperin K, et al. Psoriasis-Liver-Methotrexate Interactions. Arch Dermatol 1973; 108: 36-42.
-
(1973)
Arch Dermatol
, vol.108
, pp. 36-42
-
-
Weinstein, G.D.1
Reonigk, H.2
Maibach, H.I.3
Weinstein, G.4
Cosmides, J.5
Halperin, K.6
-
18
-
-
0027523650
-
Determinants of Serious Liver Disease among Patients Receiving Low-Dose Methotrexate for Rheumatoid Arthritis
-
Walker AM, Punch D, Dreyer NA, Tolman KG, Kremer JM, Alarcón GS, et al. Determinants of Serious Liver Disease Among Patients Receiving Low-Dose Methotrexate for Rheumatoid Arthritis. Arthritis Rheum 1993; 36: 329-35.
-
(1993)
Arthritis Rheum
, vol.36
, pp. 329-335
-
-
Walker, A.M.1
Punch, D.2
Dreyer, N.A.3
Tolman, K.G.4
Kremer, J.M.5
Alarcón, G.S.6
-
19
-
-
0024504349
-
Liver Histology in Rheumatoid Arthritis Patients Receiving Long-Term Methotrexate Therapy: A Prospective Study with Baseline and Sequential Biopsy Samples
-
Kremer LM, Lee RG, Tolman KG. Liver Histology in Rheumatoid Arthritis Patients Receiving Long-Term Methotrexate Therapy: A Prospective Study With Baseline and Sequential Biopsy Samples. Arthritis Rheum 1989; 32: 121-7.
-
(1989)
Arthritis Rheum
, vol.32
, pp. 121-127
-
-
Kremer, L.M.1
Lee, R.G.2
Tolman, K.G.3
-
20
-
-
0024438237
-
Electron Microscopic Analysis of Sequential Liver Biopsy Samples from Patients with Rheumatoid Arthritis: Correlation with Light Microscopic Findings
-
Kremer JM, Kaye GI. Electron Microscopic Analysis of Sequential Liver Biopsy Samples From Patients With Rheumatoid Arthritis: Correlation With Light Microscopic Findings. Arthritis Rheum 1989; 32: 1202-13.
-
(1989)
Arthritis Rheum
, vol.32
, pp. 1202-1213
-
-
Kremer, J.M.1
Kaye, G.I.2
-
21
-
-
0029097616
-
Light and Electron Microscopic Analysis of Sequential Liver Biopsy Samples from Patients with Rheumatoid Arthritis Receiving Long-Term Methotrexate Therapy: Follow-Up over prolonged Treatment Intervals and Correlation with Clinical and Laboratory Variables
-
Kremer JM, Kaye GI, Kaye NW, Ishak KG, Axiotiz CA. Light and Electron Microscopic Analysis of Sequential Liver Biopsy Samples From Patients With Rheumatoid Arthritis Receiving Long-Term Methotrexate Therapy: Follow-Up Over prolonged Treatment Intervals and Correlation With Clinical and Laboratory Variables. Arthritis and Rheum 1995; 38: 1194-1203.
-
(1995)
Arthritis and Rheum
, vol.38
, pp. 1194-1203
-
-
Kremer, J.M.1
Kaye, G.I.2
Kaye, N.W.3
Ishak, K.G.4
Axiotiz, C.A.5
-
22
-
-
0029916174
-
Significant Changes in Serum AST Across Hepatic Histological Biopsy Grades: An Analysis of 3 Prospective Cohorts on Methotrexate Therapy for Rheumatoid Arthritis
-
Kremer JM, Furst D, Weinblatt ME, Blotner SD. Significant Changes in Serum AST Across Hepatic Histological Biopsy Grades: An Analysis of 3 Prospective Cohorts on Methotrexate Therapy for Rheumatoid Arthritis. J Rheum 1996; 23: 459-61.
-
(1996)
J Rheum
, vol.23
, pp. 459-461
-
-
Kremer, J.M.1
Furst, D.2
Weinblatt, M.E.3
Blotner, S.D.4
-
23
-
-
0028215036
-
Methotrexate for Rheumatoid Arthritis: Suggested Guidelines for Monitoring Liver Toxicity
-
Kremer JM, Alarcon GS, Lightfoot RW, Wilkens RF, Furst DE, Williams HJ, et al. Methotrexate for Rheumatoid Arthritis: Suggested Guidelines for Monitoring Liver Toxicity. Arthritis and Rheum 1994; 37: 3:316-28.
-
(1994)
Arthritis and Rheum
, vol.37
, Issue.3
, pp. 316-328
-
-
Kremer, J.M.1
Alarcon, G.S.2
Lightfoot, R.W.3
Wilkens, R.F.4
Furst, D.E.5
Williams, H.J.6
-
25
-
-
8244261206
-
Methotrexate (MTX) Lung Toxicity: Clinical Features of Thirty-Seven Cases from Seven Rheumatology Practices
-
Kremer JM, Alarcón GS, Alexander RW, Cannon GW, et al. Methotrexate (MTX) Lung Toxicity: Clinical Features of Thirty-Seven Cases From Seven Rheumatology Practices. Arthritis Rheum 1995; 37: s205.
-
(1995)
Arthritis Rheum
, vol.37
-
-
Kremer, J.M.1
Alarcón, G.S.2
Alexander, R.W.3
Cannon, G.W.4
-
26
-
-
0028874225
-
Pharmacokinetics and Renal Function in Patients with Rheumatoid Arthritis Receiving a Standard Dose of Oral Weekly Methotrexate over a Period of 24 Months: Association with Significant Decreases in Creatinine Clearance and Renal Clearance of the Drug
-
Kremer JM, Petrillo GF, Hamilton RA. Pharmacokinetics and Renal Function in Patients With Rheumatoid Arthritis Receiving a Standard Dose of Oral Weekly Methotrexate Over a Period of 24 Months: Association With Significant Decreases in Creatinine Clearance and Renal Clearance of the Drug. J Rheumatol 1995; 22: 38-40.
-
(1995)
J Rheumatol
, vol.22
, pp. 38-40
-
-
Kremer, J.M.1
Petrillo, G.F.2
Hamilton, R.A.3
-
27
-
-
0028792273
-
The Effects of Non-Steroidal Anti-Inflammatory Drugs on Methotrexate Pharmacokinetics: Impairment of Renal Clearance of MTX at Weekly Maintenance Doses but not at 7.5 mg
-
Kremer JM, Petrillo GF, Hamilton RA. The Effects of Non-Steroidal Anti-Inflammatory Drugs on Methotrexate Pharmacokinetics: Impairment of Renal Clearance of MTX at Weekly Maintenance Doses but not at 7.5 mg. J Rheum 1995; 22: 2072-7.
-
(1995)
J Rheum
, vol.22
, pp. 2072-2077
-
-
Kremer, J.M.1
Petrillo, G.F.2
Hamilton, R.A.3
-
28
-
-
0029022389
-
Combination Therapy with Cyclosporine and Methotrexate in Severe Rheumatoid Arthritis
-
Tugwell P, Pincus T, Yocum D, Stein M, Gluck O, Kraag G. et al. Combination Therapy with Cyclosporine and Methotrexate in Severe Rheumatoid Arthritis. N Engl J Med 1995; 333: 137-41.
-
(1995)
N Engl J Med
, vol.333
, pp. 137-141
-
-
Tugwell, P.1
Pincus, T.2
Yocum, D.3
Stein, M.4
Gluck, O.5
Kraag, G.6
-
29
-
-
9244247260
-
Treatment of Rheumatoid Arthritis with Methotrexate Alone, Sulfasalazine and Hydrochloroquine, or a Combination of All Three Medications
-
O'Dell JR, Haire CE, Erikson N, Drymalski W, Palmer W, Eckhoff J, et al. Treatment of Rheumatoid Arthritis With Methotrexate Alone, Sulfasalazine and Hydrochloroquine, or a Combination of All Three Medications. N Engl J Med 1996; 334: 1287-91.
-
(1996)
N Engl J Med
, vol.334
, pp. 1287-1291
-
-
O'Dell, J.R.1
Haire, C.E.2
Erikson, N.3
Drymalski, W.4
Palmer, W.5
Eckhoff, J.6
-
30
-
-
8044220006
-
Why Intramuscular Methotrexate May be More Efficacious Than Oral Dosing in Patients with Rheumatoid Arthritis
-
in press
-
Hamilton RA, Kremer JM. Why Intramuscular Methotrexate May be More Efficacious Than Oral Dosing in Patients With Rheumatoid Arthritis. Brit J Rheum (in press), 1996.
-
(1996)
Brit J Rheum
-
-
Hamilton, R.A.1
Kremer, J.M.2
-
31
-
-
0027957782
-
The Mechanism of Action of Methotrexate in Rheumatoid Arthritis: The Search Continues
-
Kremer JM. The Mechanism of Action of Methotrexate in Rheumatoid Arthritis: The Search Continues. J Rheumatol 1994; 21: 1-5.
-
(1994)
J Rheumatol
, vol.21
, pp. 1-5
-
-
Kremer, J.M.1
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