Degradation kinetics of DMP 777, an elastase inhibitor

Pharmaceutical Research

Volumn 13, Issue 12, 1996, Pages 1815-1820

  Raghavan, Krishnaswamy S ^a,b   Gray, David B ^a   Scholz, Thomas H ^a   Nemeth, Gregory A ^a   Hussain, Munir A ^a  

^a DUPONT COMPANY   (United States)

^b BRISTOL MYERS SQUIBB   (United States)

Author keywords

Elastase inhibitor; Monocyclic lactam; NMR; Stability

Indexed keywords

BUFFER; ELASTASE INHIBITOR; N [1 (1,3 BENZODIOXOL 5 YL)BUTYL] 3,3 DIETHYL 2 [4 [(4 METHYL 1 PIPERAZINYL)CARBONYL]PHENOXY] 4 OXO 1 AZETIDINECARBOXAMIDE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; DRUG DEGRADATION; FLOW RATE; IONIC STRENGTH; KINETICS; PH; POTENTIOMETRIC TITRATION; PRIORITY JOURNAL; TEMPERATURE;

AZETIDINES; BUFFERS; DRUG STABILITY; HYDROGEN-ION CONCENTRATION; OSMOLAR CONCENTRATION; PANCREATIC ELASTASE; PIPERAZINES; SOLUTIONS; TEMPERATURE;

EID: 0030470467     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1016076907072     Document Type: Article

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