Atypical cells in effusions: Diagnostic value of cell image analysis combined with immunocytochemistry

Diagnostic Cytopathology

Volumn 15, Issue 4, 1996, Pages 263-269

  Matter Walstra, Klazien W ^a   Kraft, Rainer ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

Ber EP4 immunocytochemistry; DNA image analysis; Effusion

Indexed keywords

DNA;

ARTICLE; CANCER CYTODIAGNOSIS; CONTROLLED STUDY; DIAGNOSTIC VALUE; DNA CONTENT; EFFUSION; FEMALE; HUMAN; HUMAN CELL; IMAGE ANALYSIS; IMMUNOCYTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; TUMOR CELL;

CYTODIAGNOSIS; CYTOPHOTOMETRY; DNA; DNA, NEOPLASM; EXUDATES AND TRANSUDATES; FEMALE; HUMANS; IMAGE CYTOMETRY; IMMUNOHISTOCHEMISTRY; MALE;

EID: 0030469919     PISSN: 87551039     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0339(199611)15:4<263::AID-DC3>3.0.CO;2-F     Document Type: Article

References (20)

1. Esteban JM, Yokota S, Husain S, Battifora H. Immunocytochemical profile of benign and carcinomatous effusions. Am J Clin Pathol 1990;94:698-705.
2. Li CY, Lazcano-Villareal O, Pierre RV, Yam LT. Immunocytochemical identification of cells in serous effusions. Am J Clin Pathol 1987;88:696-706.
3. Flens MJ, Valk van der P, Tadema TM, Huysmans AC, Risse EK, Tol van GA, Meijer CJ. The contribution of immunocytochemistry in diagnostic cytology. Cancer 1990;65:2704-2711.
4. Friedlander ML, Medley DW, Taylor IW. Clinical and biological significance of aneuploidy in human tumours. J Clin Pathol 1984;37: 961-974.
5. Bacus JW, Grace LJ. Optical microscope system for standardized cell measurements and analyses. Applied Optics 1987;26: 3280-3293
6. Forsslund G, Zetterberg A. A quantitative evaluation of cytophotometric DNA analysis in retrospective studies using archival tumor specimens. Anal Quant Cytol Histol 1990;12:259-266.
7. De Angelis M, Buley ID, Heryet A, Gray W Immunocytochemical staining of serous effusions with the monoclonal antibody Ber-EP4. Cytopathology 1992;3:111-117.
8. Gaffey MJ, Mills SE, Swanson PE, Zarbo RJ, Shah AR, Wick MR. Immunoreactivity for BER-EP4 in adenocarcinomas, adenomatoid tumors, and malignant mesotheliomas. Am J Surg Pathol 1992;16: 593-599.
9. Latza U, Niedobitek G, Schwarting R, Nekarda H, Stein H. Ber-EP4: new monoclonal antibody which distinguishes epithelia from mesothelia J Clin Pathol 1990;43:213-219.
10. r 34,000 is a widely distributed human carcinoma marker. Br J Cancer 1987;56: 714-721.
11. Stoop JA, Hendriks JG, Berends D. Identification of malignant cells in serous effusions using a panel of monoclonal antibodies Ber-EP4, MCA-b-12 and EMA Cytopathology 1992;3:297-302.
12. Chatelain R, Willms A, Biesterfeld S, Auffermann W, Böcking A. Automated Feulgen staining with a temperature-controlled staining machine Anal Quant Cytol Histol 1989;11:211-217.
13. Hiddemann W, Schumann J, Andreeff M, Barlogie B, Herman CJ, Leif RC, Mayall BH, Murphy RF, Sandberg AA. Convention on nomenclature for DNA cytometry. Cytometry 1984;5:445-446.
14. Böcking A, Adler CP, Common HH, Hugarth M, Granzen B, Auffermann W. Algorithm for a DNA-cytophotometric diagnosis and grading of malignancy. Anal Quant Cytol 1984;6:1-8.
15. Andrew SM, Jasani B. An improved method for the inhibition of endogenous peroxidase non-deletenous to lymphocyte surface markers Application to immunoperoxidase studies on eosinophilrich tissue preparations. Histochem J 1987;19:426-430.
16. Koss LG. Diagnostic cytology and its histopathologic bases. 4th ed. vol. 2. Philadelphia: JB Lippincott, 1992:1082-1184.
17. Hafiz MA, Becker RL Jr, Mikel UV, Bahr GF. Cytophotometric determination of DNA in mesotheliomas and reactive mesothelial cells. Anal Quant Cytol Histol 1988;10:120-126.
18. Kobayashi TK, Gotoh T, Nakano K, Kanagawa Y, Kimura T, Sato T. Atypical mesothelial cells associated with eosinophilic pleural effusions: nuclear DNA content and immunocytochemical staining reaction with epithelial markers. Cytopathology 1993;4:37-46.
19. Fallenius AG, Auer GU, Carstensen JM. Prognostic significance of DNA measurements in 409 consecutive breast cancer patients. Cancer 1988;62:331-341.
20. McNeil BJ, Keeler E, Adelstein SJ. Primer on certain elements of medical decision making. N Engl J Med 1975;293:211-215.