Delivery of human interferon-γ via gene transfer in vitro: Prolonged expression and induction of macrophage antimicrobial activity

Journal of Interferon and Cytokine Research

Volumn 16, Issue 12, 1996, Pages 1015-1019

  Stoeckle, Mark Y ^a   Falck Pederson, Eric ^a   Rubin, Berish Y ^b   Anderson, Sylvia L ^b   Murray, Henry W ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b FORDHAM UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON;

ANTIMICROBIAL ACTIVITY; ARTICLE; CLONING VECTOR; CONTROLLED STUDY; FIBROBLAST CULTURE; GENE EXPRESSION; GENE TARGETING; GENE TRANSFER; HELA CELL; HUMAN; HUMAN CELL; LEISHMANIA DONOVANI; MACROPHAGE ACTIVATION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TOXOPLASMA GONDII;

ADENOVIRIDAE; HUMAN HERPESVIRUS 5; LEISHMANIA DONOVANI; TOXOPLASMA GONDII;

EID: 0030469563     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/jir.1996.16.1015     Document Type: Article

References (23)

1. MURRAY, H.W. (1988). Interferon-gamma, the activated macrophage, and host defense against microbial challenge. Ann. Intern. Med. 108, 596-608.
2. MURRAY, H.W. (1994). Interferon-γ and host antimicrobial defense: current and future clinical applications. Am. J. Med. 97, 459-465.
3. MULLIGAN, R.C. (1993). The basic science of gene therapy. Science 260, 926-932.
4. KOZARSKY, K.F., and WILSON, J.M. (1993). Gene therapy: adenovirus vectors. Curr. Opin. Gene. Dev. 3, 499-503.
5. ANDERSON, W.F. (1992). Human gene therapy. Science 256, 808-811.
6. HANANIA, E.G., KAVANAGH, J., HORTOBAGYI, G., GILES, R.E., CHAMPLIN, R., and DEISSEROTH, A.B. (1995). Recent advances in the application of gene therapy to human disease. Am. J. Med. 99, 537-552.
7. PRESCOTT, J.C., and FALCK-PEDERSEN, E. (1992). Varied poly(A) site efficiency in the adenovirus major late transcription unit. J. Biol. Chem. 167, 8175-8181.
8. KASS-EISLER, A., FALCK-PEDERSEN, E., ALVIRA, M., RIVERA, J., BUTTRICK, P.M., WITTENBERG, B.A., CIPRIANI, L., and LEINWAND, L.A. (1993). Quantitative determination of adenovirus-mediated gene delivery to rat cardiac myocytes in vitro and in vivo. Proc. Natl. Acad. Sci. USA 90, 11498-11502.
9. STOECKLE, M.Y. (1992). Post-transcriptional regulation of gro-α, -β, -γ and IL-8 mRNAs by IL-1β. Nucleic Acids. Res. 19, 917-920.
10. RUBIN, B.Y., BARTAL, A.H., ANDERSON, S.L., MILLET, S.K., HIRSHAUT, Y., and FEIT, C. (1983). The anticellular and protein-inducing activities of human interferon preparations are mediated by the interferon. J. Immunol. 130, 1019-1021.
11. MURRAY, H.W., RUBIN, B.Y., CARRIERO, S.M., DENN, A.T., HARRIS, A.M., and JAFFE, E.A. (1985). Human mononuclear antiprotozoal mechanisms: oxygen-dependent versus oxygen-independent activity against intracellular Toxoplasma gondii. J. Immunol. 134, 1982-1987.
12. MURRAY, H.W., RUBIN, B.Y., and ROTHERMEL, C.D. (1983). Killing of intracellular Leishmania donovani by lymphokine-stimulated human mononuclear phagocytes. Evidence that interferon-γ is the activating lymphokine. J. Clin. Invest. 72, 1506-1510.
13. WU, G.Y., and WU, C.H. (1992). Specific inhibition of hepatitis B viral gene expression in vitro by targeted antisense oligonucleotides. J. Biol. Chem. 267, 12436-12439.
14. ZHU, N., LIGGIT, D., LIU, Y., and DEBS, R. (1993). Systemic gene expression after intravenous DNA delivery into adult mice. Science 261, 209-211.
15. ROGY, M.A., AUFFENBERY, T., ESPAT, N.J., PHILIP, R., REMICK, D., WOLLENBERY, G.K., COPELAND, E.M., and MOLDAWER, L.L. (1995). Human tumor necrosis factor receptor (p55) and interleukin 10 gene transfer in the mouse reduces mortality to lethal endotoxemia and also attenuates local inflammatory responses. J. Exp. Med. 181, 2289-2293.
16. TAHARA, H., ZITVOGEL, L., STORKUS, W.J., ZEH, H.J., McKINNEY, T.G., SCHRIEBER, R.D., GUBLER, U., ROBBINS, P.D., and LOTZE, M.T. (1995). Effective eradication of established murine tumors with IL-12 gene therapy using a polycistronic retroviral vector. J. Immunol. 154, 6466-6474.
17. PORGADO, A., BANNERJI, R., WATANABE, Y., and FELDMAN, M. (1993). Antimetastatic vaccination of tumor-bearing mice with two types of IFN-γ gene-inserted tumor cells. J. Immunol. 150, 1458-1470.
18. MIZUNO, M., YOSHIDA, J., TAKAOAKA, T., and SUJITA, K. (1994). Liposomal transfection of human γ-interferon gene into human glioma cells and adoptive immunotherapy using lymphokine-activated cells. J. Neurosurg. 80, 510-514.
19. BLAU, H.M., and SPRINGER, M.L. (1995). Gene therapy - a novel form of drug delivery. N. Engl. J. Med. 333, 1204-1207.
20. HORWITZ, M.S. (1990). Adenoviridae and their replication. In: Virology, 2nd ed. B.W. Fields and D.M. Knipe (eds.) New York: Raven Press, pp. 1679-1740.
21. SCHNEIDER, M.D., and FRENCH, B.A. (1993). The advent of adenovirus gene therapy for cardiovascular disease. Circulation 88, 1937-1941.
22. LEGAL LASALLE, G., ROBERT, J.J., BERRARD, S., RIDOUX, V., STRATFORD-PERRICAUDET, L.D., PERRICAUDET, M., and MALLET, J. (1993). An adenovirus vector for gene transfer into neurons and glia in the brain. Science 259, 988-990.
23. WILSON, J.M. (1996). Adenoviruses as gene-delivery vehicles. N. Engl. J. Med. 334, 1185-1187.