Metabolic and functional consequences of successive no-flow and sustained low-flow ischaemia; A 31P MRS study in rat hearts

Journal of Molecular and Cellular Cardiology

Volumn 28, Issue 12, 1996, Pages 2373-2381

  Van Binsbergen, Xavier A ^c   Van Emous, Jan G ^c   Ferrari, Roberto ^a   Van Echteld, Cees J A ^c   Ruigrok, Tom J C ^b  

^a UNIVERSITY OF BRESCIA   (Italy)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c NONE

Author keywords

31P NMR spectroscopy; Glycolysis; Hibernation; High energy phosphates; Isolated perfused rat heart; Preconditioning

Indexed keywords

ADENOSINE TRIPHOSPHATE; CREATINE PHOSPHATE; PHOSPHATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL PH; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; HEART CONTRACTION; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE CONTRACTURE; HEART MUSCLE ISCHEMIA; HEART MUSCLE METABOLISM; HEART MUSCLE REPERFUSION; HEART VENTRICLE ENDDIASTOLIC PRESSURE; HIBERNATION; MALE; NONHUMAN; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; RAT;

EID: 0030467335     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1996.0230     Document Type: Article

References (19)

1. 87Rb NMR spectroscopic study. Magn Reson Med 34: 673-685.
2. EBERLI FR, WEINBERG EO, GRICE WN, HOROWITZ GL, APSTEIN CS, 1991. Protective effect of increased glycolytic substrate against systolic and diastolic dysfunction and increased coronary resistance from prolonged global underperfusion and reperfusion in isolated rabbit hearts perfused with erythrocyte suspensions. Circ Res 68: 466-481.
3. FERRARI R, CARGNONI A, CURELLO S, CECONI C, VOLPINI M, VISIOLI O, 1993. Metabolic adaptation of underperfused isolated rabbit heart: an insight into molecular mechanisms underlying hibernation (Abstract). Circulation 88: 1-188.
4. JANIER MF, VANOVERSCHELDE JL, BERGMANN SR, 1994. Ischemic preconditioning stimulates anaerobic glycolysis in the isolated rabbit heart. Am J Physiol 267: H1353-H1360.
5. JEREMY RW, KORETSUNE Y, MARBAN E, BECKER LC, 1992. Relation between glycolysis and calcium homeostasis in postischemic myocardium. Circ Res 70: 1180-1190.
6. KING LM, BOUCHER F, OPIE LH, 1995. Coronary flow and glucose delivery as determinants of contracture in the ischemic myocardium. J Mol Cell Cardiol 27: 701-720.
7. KINGSLEY PB, SAKO EY, YANG MQ, ZIMMER SD, UGURBIL K, FOKER JE, FROM AH, 1991. Ischemic contracture begins when anaerobic glycolysis stops: a 31P-NMR study of isolated rat hearts. Am J Physiol 261: H469-H478.
8. 2+ homeostasis during beta-adrenergic stimulation. Am J Physiol 264: H670-H678.
9. OWEN P, DENNIS S, OPIE LH, 1990. Glucose flux rate regulates onset of ischemic contracture in globally underperfused rat hearts. Circ Res 66: 344-354.
10. RAHIMTOOLA SH, 1985. A perspective on three large multicenter randomized clinical trials of coronary bypass surgery for chronic stable angina. Circulation 72: V123-V135.
11. RAHIMTOOLA SH, 1989. The hibernating myocardium. Am Heart J 117: 211-221.
12. SCHAEFER S, CARR LJ, KREUTZER U, JUE T, 1993. Myocardial adaptation during acute hibernation: mechanisms of phosphocreatine recovery. Cardiovasc Res 27: 2044-2051.
13. 31P-NMR study on isolated rat and rabbit hearts. J Mol Cell Cardiol 25: 1015-1024.
14. SCHULZ R, POST H, SAKKA S, WALLBRIDGE DR, HEUSCH G, 1995. Intraischemic preconditioning. Increased tolerance to sustained low-flow ischemia by a brief episode of no-flow ischemia without intermittent reperfusion. Circ Res 76: 942-950.
15. STEENBERGEN C, MURPHY E, WATTS JA, LONDON RE, 1990. Correlation between cytosolic free calcium, contracture, ATP, and irreversible ischemic injury in perfused rat heart. Circ Res 66: 135-146.
16. SUN D, NGUYEN N, DEGRADO TR, SCHWAIGER M, BROSIUS III FC, 1994. Ischemia induces translocation of the insulin-responsive glucose transporter GLUT4 to the plasma membrane of cardiac myocytes. Circulation 89: 793-798.
17. VANDER HEIDE RS, HILL ML, REIMER KA, JENNINGS RB, 1996. Effect of reversible ischemia on the activity of the mitochondrial ATPase: Relationship to ischemic preconditioning. J Mol Cell Cardiol 28: 103-112.
18. 0-ATPase. Circulation 91: 2810-2818.
19. 2+ transport. Circ Res 77: 88-97.