Increased expression of intercellular adhesion molecule 1, CD11/CD18 cell surface adhesion glycoproteins and α4β1 integrin in a rat model of chronic interstitial lung fibrosis

Pathobiology

Volumn 64, Issue 4, 1996, Pages 187-192

  Barquín, Nora ^a,b   Chou, Pauline ^a,b   Ramos, Carlos ^a,b   Montaño, Martha ^a,b   Pardo, Annie ^a,b   Selman, Moisés ^a,b  

^a CHILDREN'S MEMORIAL HOSPITAL   (United States)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Adhesion molecules; Fibrosis; ICAM 1; Integrins; Lung fibrosis

Indexed keywords

CD11 ANTIGEN; CD11B ANTIGEN; CD18 ANTIGEN; CELL ADHESION MOLECULE; GLYCOPROTEIN; GLYCOPROTEIN P 15095; INTEGRIN; INTERCELLULAR ADHESION MOLECULE 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; OXYGEN; PARAFORMALDEHYDE; PARAQUAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CELL INFILTRATION; CELL PROLIFERATION; CONTROLLED STUDY; FIBROBLAST; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LUNG; LUNG ALVEOLUS EPITHELIUM; LUNG FIBROSIS; LUNG INTERSTITIUM; LYMPHOCYTE; MACROPHAGE; MALE; MONONUCLEAR CELL; NONHUMAN; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIGENS, CD11; ANTIGENS, CD18; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; INTEGRIN ALPHA4BETA1; INTEGRINS; INTERCELLULAR ADHESION MOLECULE-1; MALE; PULMONARY FIBROSIS; RATS; RATS, WISTAR; RECEPTORS, LYMPHOCYTE HOMING;

EID: 0030465604     PISSN: 10152008     EISSN: 14230291     Source Type: Journal    
DOI: 10.1159/000164034     Document Type: Article

References (23)

1. Selman M: Pulmonary fibrosis: Human and experimental disease; in Rojkind M (ed): Focus on Connective Tissue in Health and Disease. Boca Raton. C'RC Press. 1989, vol I, pp 123-188.
2. Pilewski JM, Albelda SM: Adhesion molecules in the lung. An overview. Am Rev Respir Dis 1993; 148(suppl):S31-S37.
3. Carlos TM, Harlan JM: Leukocyte-endothelial adhesion molecules. Blood 1994:84:2068-2101.
4. Pardi R, Inverardi L, Bender JR: Regulatory mechanisms in leukocyte adhesion: Flexible receptors for sophisticated travellers. Immunol Today 1992;13:224-230.
5. Mulligan MS, Vaporcivan AA, Warner RL, Jones ML, Foreman KE, Miyasaka M, Todd RF III, Ward PA: Compartmentalized roles for leukocytic adhesion molecules in lung inflammatory injury. J Immunol 1995; 154:1350-1363.
6. Wegner CD, Wolyniec WW, LaPlate AM, Marschman K, Lubbe K, Haynes N, Rothlein R, Letts G: Intercellular adhesion molecule-1 contributes to pulmonary oxygen toxicity in mice: Role of leukocytes revised. Lung 1992; 170:267-279.
7. Eichacker PQ, Farese A, Hoffman WD, Banks SM, Mouginis T, Richmond S, Kuo GC. Mac-vittie TJ, Natanson T: Leukocytes CD1 1b/18 antigens-directed monoclonal antibody improves early survival and decreases hypoxemia in dogs challenged with tumor necrosis factor. Am Rev Respir Dis 1992:145:1023-1029.
8. Selman M, Montaño M, Montfort I, Pérez-Tamayo R: A new model of diffuse interstitial pulmonary fibrosis in the rat. Exp Mol Pathol 1985;43:375-387.
9. Selman M, Montano M, Ramos C, Barrios R, Perez-Tantayo R: Experimental pulmonary fibrosis induced by paraquat plus oxygen in rats: A morphologic and biochemical study. Exp Mol Pathol 1989:50:147-166.
10. Hoogsteden HC, van Hal PThW, Wijkhuijs JM, Hop W, Hilvering C: Expression of the CD I l/CD 18 cell surface adhesion glycoprotein family and MHC class II antigen on blood monocytes and alveolar macrophages in interstitial lung diseases. Lung 1992:170:221-233.
11. Striz I, Wang Y-M, Kalaycioglu O, Costabel U: Expression of alveolar macrophage adhesion molecules in pulmonary sarcoidosis. Chest 1992;102:882-886.
12. Schaberg T, Rau M, Stephan H, Lode H: Increased number of alveolar macrophages expressing surface molecule of the CD 11/CD 18 family in sarcoidosis and idiopathic pulmonary fibrosis is related to the production of superoxide anions by these cells. Am Rev Respir Dis 1993:147:1507-1513.
13. Martin WJ, Gadeck JE, Hunninghakc GW, Crystal RG: Oxidant injury of lung parenchymal cells. J Clin Invest 1981:68:1277-1288.
14. Churchill L, Gundel RH, Letts LG, Wegner CD: Contribution of specific cell-adhesive glycoproteins to airway and alveolar inflammation and dysfunction. Am Rev Respir Dis 1993:148(suppl):S83-S87.
15. Petlersen HB, Johnson E, Osen SS: Phagocytosis of agarose beads by receptors for C3b (CRI) and iC3b (CR3) on alveolar macrophages from patients with sarcoidosis. Scand J Immunol 1990:32:669-677.
16. Hamacher J, Schaberg T: Adhesion molecules in lung diseases. Lung 1994:172:189-213.
17. Dayer JM, Isler P, Nicod P: Adhesion molecules and cytokine production. Am Rev Respir Dis 1993:148(suppl):S70-S74.
18. Hill PA, Lan HY, Nikolic-Paterson DJ, Atkins RC: Pulmonary expression of ICAM-1 and LFA-I in experimental Goodpasture's syndrome. Am J Pathol 1994:145:220-227.
19. Wayner EA, Garcia-Pardo A, Humphries MJ, McDonald JA, Carter WG: Identification and characterization of the T lymphocyte adhesion receptor for an alternative cell attachment domain (CS-1) in plasma fibronectin. J Cell Biol 1989;109:1321-1330.
20. Yabkowitz R, Dixit VM, Guo N, Roberts DD, Shimizu Y: Activated T-cell adhesion to thrombospoindin is mediated by the u4pi (VLA-4) and u5bl (VLA-5) integrins. J Immunol 1993:151:149-158.
21. Werb Z, Tremble PM, Behrendtsen O, Crowley F, Damsky CH: Signal transduction through the fibronectin receptor induces collagenasc and stromelysin gene expression. J Cell Biol 1989:109:877-889.
22. +, and memory T cells to fibroblasts. J Immunol 1994:152: 4912-4918.
23. Piguet PF, Rosen H, Vesin C, Grau GE: Effective treatment of the pulmonary fibrosis elicited in mice by bleomycin or silica with anti-C'D-II antibodies. Am Rev Respir Dis 1993:147: 435-441.